Serum Levels of Free Fatty Acids in Obese Mice and Their Associations with Routine Lipid Profiles

References

• Virani SS, Alonso A, Benjamin EJ, et al. Heart disease and stroke statistics-2020 update: a report from the American Heart Association. Circulation. 2020;141(9):e139–e596. doi:10.1161/CIR.0000000000000757
   PubMed Web of Science ®Google Scholar
• D’Agostino RB, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation. 2008;117(6):743–753. doi:10.1161/CIRCULATIONAHA.107.699579
   PubMed Web of Science ®Google Scholar
• Bray GA, Heisel WE, Afshin A, et al. The science of obesity management: an endocrine society scientific statement. Endocr Rev. 2018;39(2):79–132. doi:10.1210/er.2017-00253
   PubMed Web of Science ®Google Scholar
• Huang H, Yan Z, Chen Y, Liu F. A social contagious model of the obesity epidemic. Sci Rep. 2016;6:37961. doi:10.1038/srep37961
   PubMed Web of Science ®Google Scholar
• Kyle TK, Dhurandhar EJ, Allison DB. Regarding obesity as a disease: evolving policies and their implications. Endocrinol Metab Clin North Am. 2016;45(3):511–520. doi:10.1016/j.ecl.2016.04.004
   PubMed Web of Science ®Google Scholar
• Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation. 1983;67(5):968–977. doi:10.1161/01.cir.67.5.968
   PubMed Web of Science ®Google Scholar
• Manson JE, Colditz GA, Stampfer MJ, et al. A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med. 1990;322(13):882–889. doi:10.1056/NEJM199003293221303
   PubMed Web of Science ®Google Scholar
• Elagizi A, Kachur S, Lavie CJ, et al. An overview and update on obesity and the obesity paradox in cardiovascular diseases. Prog Cardiovasc Dis. 2018;61(2):142–150. doi:10.1016/j.pcad.2018.07.003
   PubMed Web of Science ®Google Scholar
• Koliaki C, Liatis S, Kokkinos A. Obesity and cardiovascular disease: revisiting an old relationship. Metabolism. 2019;92:98–107. doi:10.1016/j.metabol.2018.10.011
   PubMed Web of Science ®Google Scholar
• Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol. 2009;53(21):1925–1932. doi:10.1016/j.jacc.2008.12.068
   PubMed Web of Science ®Google Scholar
• Ortega FB, Lavie CJ, Blair SN. Obesity and cardiovascular disease. Circ Res. 2016;118(11):1752–1770. doi:10.1161/CIRCRESAHA.115.306883
   PubMed Web of Science ®Google Scholar
• Goyal A, Nimmakayala KR, Zonszein J. Is there a paradox in obesity? Cardiol Rev. 2014;22(4):163–170. doi:10.1097/CRD.0000000000000004
   PubMed Web of Science ®Google Scholar
• Carbone S, Lavie CJ, Arena R. Obesity and heart failure: focus on the obesity paradox. Mayo Clin Proc. 2017;92(2):266–279. doi:10.1016/j.mayocp.2016.11.001
   PubMed Web of Science ®Google Scholar
• Lavie CJ, De Schutter A, Parto P, et al. Obesity and prevalence of cardiovascular diseases and prognosis-the obesity paradox updated. Prog Cardiovasc Dis. 2016;58(5):537–547. doi:10.1016/j.pcad.2016.01.008
   PubMed Web of Science ®Google Scholar
• Nordestgaard BG, Chapman MJ, Ray K, et al. Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J. 2010;31(23):2844–2853. doi:10.1093/eurheartj/ehq386
   PubMed Web of Science ®Google Scholar
• Sanin V, Pfetsch V, Koenig W. Dyslipidemias and cardiovascular prevention: tailoring treatment according to lipid phenotype. Curr Cardiol Rep. 2017;19(7):61. doi:10.1007/s11886-017-0869-3
   Web of Science ®Google Scholar
• Klop B, Elte JW, Cabezas MC. Dyslipidemia in obesity: mechanisms and potential targets. Nutrients. 2013;5(4):1218–1240. doi:10.3390/nu5041218
   PubMed Web of Science ®Google Scholar
• Goel A, Pothineni NV, Singhal M, Paydak H, Saldeen T, Mehta JL. Oils and cardioprotection: promise or fish tale? Int J Mol Sci. 2018;19(12):3703. doi:10.3390/ijms19123703
   Web of Science ®Google Scholar
• Shahidi F, Ambigaipalan P. Omega-3 polyunsaturated fatty acids and their health benefits. Annu Rev Food Sci Technol. 2018;9:345–381. doi:10.1146/annurev-food-111317-095850
   PubMed Web of Science ®Google Scholar
• Bang HO, Dyerberg J, Nielsen AB. Plasma lipid and lipoprotein pattern in Greenlandic West-coast Eskimos. Lancet. 1971;297(7710):1143–1145. doi:10.1016/s0140-6736(71)91658-8
   Web of Science ®Google Scholar
• Sobczak A, Blindauer C, Stewart A. Changes in plasma free fatty acids associated with type-2 diabetes. Nutrients. 2019;11(9). doi:10.3390/nu11092022
   Web of Science ®Google Scholar
• Calder PC. Functional roles of fatty acids and their effects on human health. JPEN J Parenter Enteral Nutr. 2015;39(1 Suppl):18s–32s. doi:10.1177/0148607115595980
   PubMed Web of Science ®Google Scholar
• Mensink RP, Katan MB. Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials. Arterioscleros Thrombos. 1992;12(8):911–919. doi:10.1161/01.atv.12.8.911
   PubMed Web of Science ®Google Scholar
• Mensink RP, Zock PL, Kester AD, Katan MB. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr. 2003;77(5):1146–1155. doi:10.1093/ajcn/77.5.1146
   PubMed Web of Science ®Google Scholar
• Harris WS, Zotor FB. n-3 fatty acids and risk for fatal coronary disease. Proc Nutr Soc. 2019;78(4):526–531. doi:10.1017/S0029665118002902
   Web of Science ®Google Scholar
• Mozaffarian D, Wu JH. Omega-3 fatty acids and cardiovascular disease: effects on risk factors, molecular pathways, and clinical events. J Am Coll Cardiol. 2011;58(20):2047–2067. doi:10.1016/j.jacc.2011.06.063
   PubMed Web of Science ®Google Scholar
• Sioen I, van Lieshout L, Eilander A, et al. Systematic review on N-3 and N-6 polyunsaturated fatty acid intake in European countries in light of the current recommendations - focus on specific population groups. Ann Nutr Metab. 2017;70(1):39–50. doi:10.1159/000456723
   Web of Science ®Google Scholar
• Food and Agriculture Organization of the United Nations. Fats and fatty acids in human nutrition. Report of an expert consultation. FAO Food Nutr Pap. 2010;91:1–166.
   PubMedGoogle Scholar
• Bowman L, Mafham M, Wallendszus K, et al. Effects of n-3 fatty acid supplements in diabetes mellitus. N Engl J Med. 2018;379(16):1540–1550. doi:10.1056/NEJMoa1804989
   PubMed Web of Science ®Google Scholar
• Jaca A, Durao S, Harbron J. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. South African Med J. 2020;110(12):1158–1159. doi:10.7196/SAMJ.2020.v110i12.14730
   Web of Science ®Google Scholar
• Manson JE, Cook NR, Lee IM, et al. Marine n-3 fatty acids and prevention of cardiovascular disease and cancer. N Engl J Med. 2019;380(1):23–32. doi:10.1056/NEJMoa1811403
   PubMed Web of Science ®Google Scholar
• Žáček P, Bukowski M, Mehus A, et al. Dietary saturated fatty acid type impacts obesity-induced metabolic dysfunction and plasma lipidomic signatures in mice. J Nutr Biochem. 2019;64:32–44. doi:10.1016/j.jnutbio.2018.10.005
   PubMed Web of Science ®Google Scholar
• Ramsden CE, Hibbeln JR, Majchrzak SF, Davis JM. n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials. Br J Nutr. 2010;104(11):1586–1600. doi:10.1017/S0007114510004010
   PubMed Web of Science ®Google Scholar
• Calder PC. Old study sheds new light on the fatty acids and cardiovascular health debate. BMJ. 2013;346:f493. doi:10.1136/bmj.f493
   Web of Science ®Google Scholar
• Van Name MA, Savoye M, Chick JM, et al. A low ω-6 to ω-3 PUFA ratio (n-6: n-3PUFA) diet to treat fatty liver disease in obese youth. J Nutr. 2020;150(9):2314–2321. doi:10.1093/jn/nxaa183
   Web of Science ®Google Scholar
• Boden G. Obesity and free fatty acids. Endocrinol Metab Clin North Am. 2008;37(3):635–646, viii–ix. doi:10.1016/j.ecl.2008.06.007
   PubMed Web of Science ®Google Scholar
• Kaikkonen JE, Jula A, Viikari JSA, et al. Associations of serum fatty acid proportions with obesity, insulin resistance, blood pressure, and fatty liver: the cardiovascular risk in young finns study. J Nutr. 2021;151(4):970–978. doi:10.1093/jn/nxaa409
   Web of Science ®Google Scholar
• Gowda SGB, Gao ZJ, Chen Z, et al. Untargeted lipidomic analysis of plasma from high-fat diet-induced obese rats using UHPLC-linear trap quadrupole-orbitrap MS. Anal Sci. 2020;36(7):821–828. doi:10.2116/analsci.19P442
   Web of Science ®Google Scholar