Relationship Between the Triglyceride-Glucose Index and Type 2 Diabetic Macroangiopathy: A Single-Center Retrospective Analysis

References

• Wang L, Gao P, Zhang M, et al. Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013. JAMA. 2017;317(24):2515–2523. doi:10.1001/jama.2017.7596
   PubMed Web of Science ®Google Scholar
• Roberts NL, Mountjoy-Venning WC, Anjomshoa M, Banoub JA, Yasin YJ. Global, regional, and national incidence, prevalence, and years lived with disability for R354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1789–1858. doi:10.1016/S0140-6736(18)32279-7
   Web of Science ®Google Scholar
• Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018;14(2):88–98. doi:10.1038/nrendo.2017.151
   PubMed Web of Science ®Google Scholar
• Bornfeldt KE, Tabas I. Insulin resistance, hyperglycemia, and atherosclerosis. Cell Metab. 2011;14(5):575–585. doi:10.1016/j.cmet.2011.07.015
   PubMed Web of Science ®Google Scholar
• Mohd Nor NS, Lee S, Bacha F, Tfayli H, Arslanian S. Triglyceride glucose index as a surrogate measure of insulin sensitivity in obese adolescents with normoglycemia, prediabetes, and type 2 diabetes mellitus: comparison with the hyperinsulinemic-euglycemic clamp. Pediatr Diabetes. 2016;17(6):458–465. doi:10.1111/pedi.12303
   PubMed Web of Science ®Google Scholar
• Guerrero-Romero F, Simental-Mendía LE, González-Ortiz M, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab. 2010;95(7):3347–3351. doi:10.1210/jc.2010-0288
   PubMed Web of Science ®Google Scholar
• Chamroonkiadtikun P, Ananchaisarp T, Wanichanon W. The triglyceride-glucose index, a predictor of type 2 diabetes development: a retrospective cohort study. Prim Care Diabetes. 2020;14(2):161–167. doi:10.1016/j.pcd.2019.08.004
   PubMed Web of Science ®Google Scholar
• Vasques AC, Novaes FS, de Oliveira Mda S, et al. TyG index performs better than HOMA in a Brazilian population: a hyperglycemic clamp validated study. Diabetes Res Clin Pract. 2011;93(3):e98–e100. doi:10.1016/j.diabres.2011.05.030
   PubMed Web of Science ®Google Scholar
• Navarro-González D, Sánchez-Íñigo L, Pastrana-Delgado J, Fernández-Montero A, Martinez JA. Triglyceride-glucose index (TyG index) in comparison with fasting plasma glucose improved diabetes prediction in patients with normal fasting glucose: the Vascular-Metabolic CUN cohort. Prev Med. 2016;86:99–105. doi:10.1016/j.ypmed.2016.01.022
   PubMed Web of Science ®Google Scholar
• Fiorentino TV, Marini MA, Succurro E, Andreozzi F, Sesti G. Relationships of surrogate indexes of insulin resistance with insulin sensitivity assessed by euglycemic hyperinsulinemic clamp and subclinical vascular damage. BMJ Open Diabetes Res Care. 2019;7(1):e000911. doi:10.1136/bmjdrc-2019-000911
   PubMed Web of Science ®Google Scholar
• Wang S, Shi J, Peng Y, et al. Stronger association of triglyceride glucose index than the HOMA-IR with arterial stiffness in patients with type 2 diabetes: a real-world single-centre study. Cardiovasc Diabetol. 2021;20(1):82. doi:10.1186/s12933-021-01274-x
   PubMed Web of Science ®Google Scholar
• Xu X, Huang R, Lin Y, et al. High triglyceride-glucose index in young adulthood is associated with incident cardiovascular disease and mortality in later life: insight from the CARDIA study. Cardiovasc Diabetol. 2022;21(1):155. doi:10.1186/s12933-022-01593-7
   Web of Science ®Google Scholar
• Cao Y, Zhang D, Cai Z, Gong P, Li L. The relationship between the calcification score of the siphon of the internal carotid artery and the initial vascular stenosis. Chin J Arterioscler. 2017;25(04):378–382.
   Google Scholar
• Liu L, Qian Y, Li L, et al. Correlation between cervical and femoral artery intima-media thickness and coronary heart disease evaluated by ultrasound. Chin J Ultrasound Med. 2006;32(02):117–119. doi:10.1016/j.ultrasmedbio.2006.02.443
   Google Scholar
• Low Wang CC, Hess CN, Hiatt WR, Goldfine AB. Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus - mechanisms, management, and clinical considerations. Circulation. 2016;133(24):2459–2502. doi:10.1161/CIRCULATIONAHA.116.022194
   PubMed Web of Science ®Google Scholar
• Lathief S, Inzucchi SE. Approach to diabetes management in patients with CVD. Trends Cardiovasc Med. 2016;26(2):165–179. doi:10.1016/j.tcm.2015.05.005
   Web of Science ®Google Scholar
• Beddhu S. The body mass index paradox and an obesity, inflammation, and atherosclerosis syndrome in chronic kidney disease. Semin Dial. 2004;17(3):229–232. doi:10.1111/j.0894-0959.2004.17311.x
   Web of Science ®Google Scholar
• Rocha VZ, Libby P. Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol. 2009;6(6):399–409. doi:10.1038/nrcardio.2009.55
   PubMed Web of Science ®Google Scholar
• Beverly JK, Budoff MJ. Atherosclerosis: pathophysiology of insulin resistance, hyperglycemia, hyperlipidemia, and inflammation. J Diabetes. 2020;12(2):102–104. doi:10.1111/1753-0407.12970
   PubMed Web of Science ®Google Scholar
• Reardon CA, Lingaraju A, Schoenfelt KQ, et al. Obesity and insulin resistance promote atherosclerosis through an IFNγ-regulated macrophage protein network. Cell Rep. 2018;23(10):3021–3030. doi:10.1016/j.celrep.2018.05.010
   Web of Science ®Google Scholar
• Xue Y, Lin S, Jia J, Yan T. Analysis of vascular calcification and its risk factors in uremic patients with diabetic nephropathy. J Jilin Univ. 2010;36(05):946–951.
   Google Scholar
• Schauer IE, Snell-Bergeon JK, Bergman BC, et al. Insulin resistance, defective insulin-mediated fatty acid suppression, and coronary artery calcification in subjects with and without type 1 diabetes: the CACTI study. Diabetes. 2011;60(1):306–314. doi:10.2337/db10-0328
   PubMed Web of Science ®Google Scholar
• Poon AK, Whitsel EA, Heiss G, et al. Insulin resistance and reduced cardiac autonomic function in older adults: the atherosclerosis risk in communities study. BMC Cardiovasc Disord. 2020;20(1):217. doi:10.1186/s12872-020-01496-z
   Web of Science ®Google Scholar
• Kaaja RJ, Pöyhönen-Alho MK. Insulin resistance and sympathetic overactivity in women. J Hypertens. 2006;24(1):131–141. doi:10.1097/01.hjh.0000194121.19851.e5
   PubMed Web of Science ®Google Scholar
• Tohidi M, Baghbani-Oskouei A, Ahanchi NS, Azizi F, Hadaegh F. Fasting plasma glucose is a stronger predictor of diabetes than triglyceride-glucose index, triglycerides/high-density lipoprotein cholesterol, and homeostasis model assessment of insulin resistance: Tehran Lipid and Glucose Study. Acta Diabetol. 2018;55(10):1067–1074. doi:10.1007/s00592-018-1195-y
   Web of Science ®Google Scholar
• Low S, Khoo KCJ, Irwan B, et al. The role of triglyceride glucose index in development of Type 2 diabetes mellitus. Diabetes Res Clin Pract. 2018;143:43–49. doi:10.1016/j.diabres.2018.06.006
   PubMed Web of Science ®Google Scholar
• Beckman JA, Paneni F, Cosentino F, Creager MA. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II. Eur Heart J. 2013;34(31):2444–2452. doi:10.1093/eurheartj/eht142
   PubMed Web of Science ®Google Scholar
• Wu S, Liu W, Ma Q, et al. Association between insulin resistance and coronary plaque vulnerability in patients with acute coronary syndromes: insights from optical coherence tomography. Angiology. 2019;70(6):539–546. doi:10.1177/0003319718809931
   PubMed Web of Science ®Google Scholar
• Kedhi E, Kennedy MW, Maehara A, et al. Impact of TCFA on unanticipated ischemic events in medically treated diabetes mellitus: insights from the PROSPECT study. JACC Cardiovasc Imaging. 2017;10(4):451–458. doi:10.1016/j.jcmg.2015.12.023
   Web of Science ®Google Scholar
• Hong S, Han K, Park CY. The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study. BMC Med. 2020;18(1):361. doi:10.1186/s12916-020-01824-2
   PubMed Web of Science ®Google Scholar
• Su WY, Chen SC, Huang YT, et al. Comparison of the effects of fasting glucose, hemoglobin A(1c), and triglyceride-glucose index on cardiovascular events in type 2 diabetes mellitus. Nutrients. 2019;11(11):2838. doi:10.3390/nu11112838
   PubMed Web of Science ®Google Scholar
• Kim MK, Ahn CW, Kang S, Nam JS, Kim KR, Park JS. Relationship between the triglyceride glucose index and coronary artery calcification in Korean adults. Cardiovasc Diabetol. 2017;16(1):108. doi:10.1186/s12933-017-0589-4
   PubMed Web of Science ®Google Scholar
• Li S, Guo B, Chen H, et al. The role of the triglyceride (triacylglycerol) glucose index in the development of cardiovascular events: a retrospective cohort analysis. Sci Rep. 2019;9(1):7320. doi:10.1038/s41598-019-43776-5
   Web of Science ®Google Scholar
• Sánchez-Íñigo L, Navarro-González D, Fernández-Montero A, Pastrana-Delgado J, Martínez JA. The TyG index may predict the development of cardiovascular events. Eur J Clin Invest. 2016;46(2):189–197. doi:10.1111/eci.12583
   PubMed Web of Science ®Google Scholar
• Cho YR, Ann SH, Won KB, et al. Association between insulin resistance, hyperglycemia, and coronary artery disease according to the presence of diabetes. Sci Rep. 2019;9(1):6129. doi:10.1038/s41598-019-42700-1
   PubMed Web of Science ®Google Scholar