References
- FlowerRJVaneJRInhibition of prostaglandin synthetase in brain explains the antipyretic activity of paracetamol (4-acetamidophenol)Nature197224053814104114564318
- Muth-SelbachUSTegederIBruneKGeisslingerGAcetaminophen inhibits spinal prostaglandin E2 release after peripheral noxious stimulationAnesthesiology199991123123910422949
- PickeringGLoriotMALibertFEschalierABeaunePDubrayCAnalgesic effect of acetaminophen in humans: first evidence of a central serotonergic mechanismClin Pharmacol Ther200679437137816580905
- PickeringGEstèveVLoriotMAEschalierADubrayCAcetaminophen reinforces descending inhibitory pain pathwaysClin Pharmacol Ther2008841475117957182
- OttaniALeoneSSandriniMFerrariABertoliniAThe analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptorsEur J Pharmacol20065311–328028116438952
- MalletCDaulhacLBonnefontJEndocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesiaPain2008139119020018485596
- MalletCBarrièreDAErmundAJönssonBAEschalierAZygmuntPMHögestättEDTRPV1 in brain is involved in acetaminophen-induced antinociceptionPLoS One201059 pii:e12748
- AyoubSSPryceGSeedMPBoltonCFlowerRJBakerDParacetamol-induced hypothermia is independent of cannabinoids and transient receptor potential vanilloid-1 and is not mediated by AM404Drug Metab Dispos20113991689169521628499
- FuJBottegoniGSassoOA catalytically silent FAAH-1 variant drives anandamide transport in neuronsNat Neurosci2011151646922101642
- HögestättEDJönssonBAErmundAConversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous systemJ Biol Chem200528036314053141215987694
- ZygmuntPMChuangHMovahedPJuliusDHögestättEDThe anandamide transport inhibitor AM404 activates vanilloid receptorsEur J Pharmacol20003961394210822052
- CostaBSiniscalcoDTrovatoAAM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic painBr J Pharmacol200614871022103216770320
- DoigGSSimpsonFRandomization and allocation concealment: a practical guide for researchersJ Crit Care200520218719316139163
- LongJHControl of analgesic and anti-inflammatory pathways by fatty acid amide hydrolase [thesis]Queen MaryUniversity of London2012
- GiuffridaABeltramoMPiomelliDMechanisms of endocannabinoid inactivation: biochemistry and pharmacologyJ Pharmacol Exp Ther2001298171411408519
- BeltramoMStellaNCalignanoALinSYMakriyannisAPiomelliDFunctional role of high-affinity anandamide transport, as revealed by selective inhibitionScience19972775329109410979262477
- La RanaGRussoRCampolongoPModulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-Hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide]J Pharmacol Exp Ther200631731365137116510698
- BarrièreDAMalletCBlomgrenAFatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brainPLoS One201388e7069023940628
- MuramatsuSShiraishiSMiyanoKMetabolism of AM404 from acetaminophen at human therapeutic dosages in the rat brainAnesth Pain Med201661e3287327110534
- MalmbergABYakshTLCapsaicin-evoked prostaglandin E2 release in spinal cord slices: relative effect of cyclooxygenase inhibitorsEur J Pharmacol19942712–32932997705429
- AyoubSSColville-NashPRWilloughbyDABottingRMThe involvement of a cyclooxygenase 1 gene-derived protein in the antinociceptive action of paracetamol in miceEur J Pharmacol20065381–3576516674937
- KumpulainenEKokkiHHalonenTHeikkinenMSavolainenJLaisalmiMParacetamol (acetaminophen) penetrates readily into the cerebrospinal fluid of children after intravenous administrationPediatrics2007119476677117403848
- SinglaNKParulanCSamsonRPlasma and cerebrospinal fluid pharmacokinetic parameters after single-dose administration of intravenous, oral, or rectal acetaminophenPain Pract201212752353222524979