Epilepsy in patients with autism: links, risks and treatment challenges

References

• AmietCGourfinkel-AnIBouzamondoAEpilepsy in autism is associated with intellectual disability and gender: evidence from a meta-analysisBiol Psychiatry200864757758218565495
   PubMed Web of Science ®Google Scholar
• RussSALarsonKHalfonNA national profile of childhood epilepsy and seizure disorderPediatrics2012129225626422271699
   PubMed Web of Science ®Google Scholar
• ReillyCAtkinsonPDasKBNeurobehavioral comorbidities in children with active epilepsy: a population-based studyPediatrics20141336e1586e159324864167
   PubMed Web of Science ®Google Scholar
• KannerLAutistic disturbances of affective contactNerv Child194323217250
   Google Scholar
• TuchmanRRapinIEpilepsy in autismLancet Neurol20021635235812849396
   PubMed Web of Science ®Google Scholar
• BesagFMCurrent controversies in the relationships between autism and epilepsyEpilepsy Behav20154714314626091860
   PubMed Web of Science ®Google Scholar
• SillanpääMBesagFAldenkampACaplanRDunnDWGobbiGPsychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report): epidemiology of psychiatric/behavioural disorder in children with epilepsyEpileptic Disord201618s1S2S7
   Google Scholar
• LotterVEpidemiology of autistic conditions in young childrenSoc Psychiatry Psychiatric Epidemiol196613124135
   Google Scholar
• BairdGSimonoffEPicklesAPrevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP)Lancet2006368953121021516844490
   PubMed Web of Science ®Google Scholar
• FombonneEEstimated prevalence of autism spectrum conditions in Cambridgeshire is over 1%Evidence Based Mental Health20101313220164529
   PubMedGoogle Scholar
• KimYSFombonneEKohYJKimSJCheonKALeventhalBLA comparison of DSM-IV pervasive developmental disorder and DSM-5 autism spectrum disorder prevalence in an epidemiologic sampleJ Am Acad Child Adolesc Psychiatry201453550050824745950
   PubMed Web of Science ®Google Scholar
• GillbergCSteffenburgSOutcome and prognostic factors in infantile autism and similar conditions: a population-based study of 46 cases followed through pubertyJ Autism Dev Disord19871722732873610999
   PubMed Web of Science ®Google Scholar
• VolkmarFRNelsonDSSeizure disorders in autismJ Am Acad Child Adolesc Psychiatry19902911271292295565
   PubMed Web of Science ®Google Scholar
• El AchkarCMSpenceSJClinical characteristics of children and young adults with co-occurring autism spectrum disorder and epilepsyEpilepsy Behav20154718319025599987
   PubMed Web of Science ®Google Scholar
• BoltonPFCarcani-RathwellIHuttonJGoodeSHowlinPRutterMEpilepsy in autism: features and correlatesBr J Psychiatry2011198428929421972278
   PubMedGoogle Scholar
• DaviesSHeymanIGoodmanRA population survey of mental health problems in children with epilepsyDev Med Child Neurol200345529229512729141
   PubMed Web of Science ®Google Scholar
• LandauWMKleffnerFRSyndrome of acquired aphasia with convulsive disorder in childrenNeurology1957752353013451887
   PubMed Web of Science ®Google Scholar
• DeonnaTWAcquired epileptiform aphasia in children (Landau-Kleffner syndrome)J Neurophysiol199183288298
   Web of Science ®Google Scholar
• Roulet PerezEDavidoffVDesplandPADeonnaTMental and behavioural deterioration of children with epilepsy and CSWS: acquired epileptic frontal syndromeDev Med Child Neurol19933586616748335156
   PubMedGoogle Scholar
• DeonnaTBeaumanoirAGaillardFAssalGAcquired aphasia in childhood with seizure disorder: a heterogeneous syndromeNeuropadiatrie197783263273578297
   PubMedGoogle Scholar
• ParrJRLe CouteurABairdGEarly developmental regression in autism spectrum disorder: evidence from an international multiplex sampleJ Autism Dev Disord201141333234020711649
   PubMedGoogle Scholar
• IrwinKBirchVLeesJMultiple subpial transection in Landau-Kleffner syndromeDev Med Child Neurol200143424825211305402
   PubMedGoogle Scholar
• DeonnaTRouletEAutistic spectrum disorder: evaluating a possible contributing or causal role of epilepsyEpilepsia200647Suppl 27982
   Google Scholar
• BairdGRobinsonROBoydSCharmanTSleep electroencephalograms in young children with autism with and without regressionDev Med Child Neurol200648760460816780632
   PubMed Web of Science ®Google Scholar
• BesagFMCBehavioral aspects of pediatric epilepsy syndromesEpilepsy Behav20045Suppl 1S3S13
   Google Scholar
• PavonePStrianoPFalsaperlaRPavoneLRuggieriMInfantile spasms syndrome, West syndrome and related phenotypes: what we know in 2013Brain Dev201436973975124268986
   PubMed Web of Science ®Google Scholar
• BoltonPFParkRJHigginsJNGriffithsPDPicklesANeuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complexBrain2002125Pt 61247125512023313
   PubMedGoogle Scholar
• JambaqueIMottronLChironCNeuropsychological outcome in children with West syndromeJambaqueILassondeMDulacONeuropsychology of Childhood EpilepsyNew YorkKluwer Academic/Plenum Publishers2001175183
   Google Scholar
• BetancurCEtiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still countingBrain Res20111380427721129364
   PubMed Web of Science ®Google Scholar
• SzatmariPJonesMBIQ and the genetics of autismJ Child Psychol Psychiatry19913268979081744193
   PubMed Web of Science ®Google Scholar
• CharmanTPicklesASimonoffEChandlerSLoucasTBairdGIQ in children with autism spectrum disorders: data from the Special Needs and Autism Project (SNAP)Psychol Med201141361962721272389
   PubMed Web of Science ®Google Scholar
• ForsgrenLEdvinssonSOBlomquistHKHeijbelJSidenvallREpilepsy in a population of mentally retarded children and adultsEpilepsy Res1990632342482148725
   PubMedGoogle Scholar
• SteffenburgUHagbergGViggedalGKyllermanMActive epilepsy in mentally retarded children. I. Prevalence and additional neuro-impairmentsActa Paediatri1995841011471152
   Web of Science ®Google Scholar
• CanpolatMPerHGumusHRapamycin has a beneficial effect on controlling epilepsy in children with tuberous sclerosis complex: results of 7 children from a cohort of 86Childs Nerv Syst201430222724023743820
   PubMedGoogle Scholar
• FrenchJALawsonJAYapiciZAdjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled studyLancet2016388100562153216327613521
   PubMed Web of Science ®Google Scholar
• PaciorkowskiARFangMChromosomal microarray interpretation: what is a child neurologist to do?Pediatr Neurol200941639139819931159
   PubMed Web of Science ®Google Scholar
• LeeBHSmithTPaciorkowskiARAutism spectrum disorder and epilepsy: disorders with a shared biologyEpilepsy Behav20154719120125900226
   PubMed Web of Science ®Google Scholar
• BlackmonKStructural MRI biomarkers of shared pathogenesis in autism spectrum disorder and epilepsyEpilepsy Behav20154717218225812936
   PubMed Web of Science ®Google Scholar
• MargariLPalumbiRCampaMGClinical manifestations in children and adolescents with corpus callosum abnormalitiesJ Neurol2016263101939194527383641
   PubMed Web of Science ®Google Scholar
• SundelinHELarssonHLichtensteinPAutism and epilepsy: a population-based nationwide cohort studyNeurology201687219219727306624
   PubMedGoogle Scholar
• BesagFMRate of epilepsy in people with autism and the rate of autism in people with epilepsy are highEvid Based Med201621623027884885
   PubMedGoogle Scholar
• BaieliSPavoneLMeliCFiumaraAColemanMAutism and phenylketonuriaJ Autism Dev Disord200333220120412757360
   PubMed Web of Science ®Google Scholar
• SchmidtRJLyallKHertz-PicciottoIEnvironment and autism: current state of the scienceCut Edge Psychiatry Pract201414213827453776
   PubMedGoogle Scholar
• ChessSFollow-up report on autism in congenital rubellaJ Autism Child Schizophr1977716981576606
   PubMedGoogle Scholar
• MeadorKJLoringDWPrenatal valproate exposure is associated with autism spectrum disorder and childhood autismJ Pediatr20131633924
   Google Scholar
• ChristensenJGronborgTKSorensenMJPrenatal valproate exposure and risk of autism spectrum disorders and childhood autismJAMA2013309161696170323613074
   PubMed Web of Science ®Google Scholar
• KubanKCJosephRMO’sheaTMGirls and boys born before 28 weeks gestation: risks of cognitive, behavioral, and neurologic outcomes at age 10 yearsJ Pediatr20161736975.e6127004675
   PubMed Web of Science ®Google Scholar
• SinghRTurnerRCNguyenLMotwaniKSwatekMLucke-WoldBPPediatric traumatic brain injury and autism: elucidating shared mechanismsBehav Neurol20162016878172528074078
   PubMed Web of Science ®Google Scholar
• FryeREMetabolic and mitochondrial disorders associated with epilepsy in children with autism spectrum disorderEpilepsy Behav20154714715725440829
   PubMed Web of Science ®Google Scholar
• KruegerDANorthrupHGroup ITSCCTuberous sclerosis complex surveillance and management: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus ConferencePediatr Neurol201349425526524053983
   PubMed Web of Science ®Google Scholar
• AldenkampABesagFGobbiGCaplanRDunnDWSillanpääMPsychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report): adverse cognitive and behavioural effects of antiepileptic drugs in childrenEpileptic Disord201618s1S55S67
   Google Scholar
• BrodieMJBesagFEttingerABEpilepsy, antiepileptic drugs, and aggression: an evidence-based reviewPharmacol Rev201668356360227255267
   PubMedGoogle Scholar
• VincentABienCGIraniSRWatersPAutoantibodies associated with diseases of the CNS: new developments and future challengesLancet Neurol201110875977221777830
   PubMed Web of Science ®Google Scholar
• IraniSRGelfandJMAl-DiwaniAVincentACell-surface central nervous system autoantibodies: clinical relevance and emerging paradigmsAnn Neurol201476216818424930434
   PubMed Web of Science ®Google Scholar
• DaltonPDeaconRBlamireAMaternal neuronal antibodies associated with autism and a language disorderAnn Neurol200353453353712666123
   PubMed Web of Science ®Google Scholar
• BesagFGobbiGCaplanRSillanpääMAldenkampADunnDWPsychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report): epilepsy and ADHDEpileptic Disord201618s1S8S15
   Google Scholar
• GucuyenerKErdemogluAKSenolSSerdarogluASoysalSKockarAIUse of methylphenidate for attention-deficit hyperactivity disorder in patients with epilepsy or electroencephalographic abnormalitiesJ Child Neurol200318210911212693777
   PubMed Web of Science ®Google Scholar
• HemmerSAPasternakJFZeckerSGTrommerBLStimulant therapy and seizure risk in children with ADHDPediatr Neurol20012429910211275457
   PubMed Web of Science ®Google Scholar
• DunnDWBesagFCaplanRAldenkampAGobbiGSillanpääMPsychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report): anxiety, depression and childhood epilepsyEpileptic Disord201618s1S24S30
   Google Scholar
• McDougleCJScahillLAmanMGRisperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacologyAm J Psychiatry200516261142114815930063
   PubMed Web of Science ®Google Scholar
• HolzhausenSPGuerreiroMMBaccinCEMontenegroMAUse of risperidone in children with epilepsyEpilepsy Behav200710341241617382594
   PubMed Web of Science ®Google Scholar
• SpinaEAvenosoAFacciolaGPlasma concentrations of risperidone and 9-hydroxyrisperidone: effect of comedication with carbamazepine or valproateTher Drug Monit200022448148510942191
   PubMed Web of Science ®Google Scholar
• Gail WilliamsPSearsLLAllardASleep problems in children with autismJ Sleep Res200413326526815339262
   PubMed Web of Science ®Google Scholar
• MalowBASleep disorders, epilepsy, and autismMent Retard Dev Disabil Res Rev200410212212515362168
   PubMedGoogle Scholar
• JainSBesagFMDoes melatonin affect epileptic seizures?Drug Saf201336420721523532506
   PubMed Web of Science ®Google Scholar
• LimaECabralFRCavalheiroEANaffah-MazzacorattiMGAmadoDMelatonin administration after pilocarpine-induced status epilepticus: a new way to prevent or attenuate postlesion epilepsy?Epilepsy Behav201120460761221454134
   PubMed Web of Science ®Google Scholar
• SolmazIGurkanlarDGokcilZGoksoyCOzkanMErdoganEAntiepileptic activity of melatonin in guinea pigs with pentylenetetrazol-induced seizuresNeurol Res200931998999519138464
   PubMed Web of Science ®Google Scholar