155
Views
33
CrossRef citations to date
0
Altmetric
Original Research

Influence of dose, gender, and cigarette smoking on clozapine plasma concentrations

, , , , &
Pages 1535-1543 | Published online: 14 Jun 2018

References

  • HasanAFalkaiPWobrockTWorld Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of Schizophrenia, Part 1: update 2012 on the acute treatment of schizophrenia and the management of treatment resistanceWorld J Biol Psychiatry201213531837822834451
  • LandRSiskindDMcArdlePKiselySWinckelKHollingworthSThe impact of clozapine on hospital use: a systematic review and meta-analysisActa Psychiatr Scand2017135429630928155220
  • BachmannCJAagaardLBernardoMInternational trends in clozapine use: a study in 17 countriesActa Psychiatr Scand20171361375128502099
  • KimJSParkCMChoiJThe association between season of birth, age at onset, and clozapine use in schizophreniaActa Psychiatr Scand2017136544545428741647
  • IqbalMMSwatiSAnejaAIqbalMTAnejaEHaqueSMost common side effects of clozapine and their managementInt J Emerg Ment Health201618416
  • HonigfeldGArellanoFSethiJBianchiniAScheinJReducing clozapine-related morbidity and mortality: 5 years of experience with the Clozaril National RegistryJ Clin Psychiatry199859Suppl 337
  • HiemkeCBergemannNClementHWConsensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017Pharmacopsychiatry2018511–296228910830
  • KhanAPreskornSExamining concentration-dependent toxicity of clozapine: role of therapeutic drug monitoringJ Psychiatr Pract200511528930116184070
  • CouchmanLMorganPESpencerEPFlanaganRJPlasma clozapine, norclozapine, and the clozapine:norclozapine ratio in relation to prescribed dose and other factors: data from a therapeutic drug monitoring service, 1993–2007Ther Drug Monit201032443844720463634
  • TangYLMaoPLiFMGender, age, smoking behaviour and plasma clozapine concentrations in 193 Chinese inpatients with schizophreniaBr J Clin Pharmacol2007641495617298477
  • GaertnerIGaertnerHLampeDTherapeutic drug monitoring of clozapine and olanzapine. Similarities and differencesPsychopharmakotherap199963105109
  • RajkumarAPPoonkuzhaliBKuruvillaAJacobMJacobKSClinical predictors of serum clozapine levels in patients with treatment-resistant schizophreniaInt Clin Psychopharmacol2013281505623104241
  • LaneHYChangYCChangWHLinSKTsengYTJannMWEffects of gender and age on plasma levels of clozapine and its metabolites: analyzed by critical statisticsJ Clin Psychiatry19996013640
  • JannMWLiuHCWeiFCLinSKHuWHChangWHGender differences in plasma clozapine levels and its metabolites in schizophrenic patientsHum Psychopharmacol1997125489495
  • UlrichSBaumannBWolfRTherapeutic drug monitoring of clozapine and relapse – a retrospective study of routine clinical dataInt J Clin Pharmacol Ther200341131312564740
  • Rostami-HodjeganAAminAMSpencerEPLennardMSTuckerGTFlanaganRJInfluence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patientsJ Clin Psychopharmacol2004241707814709950
  • BowskillSCouchmanLMacCabeJHFlanaganRJPlasma clozapine and norclozapine in relation to prescribed dose and other factors in patients aged 65 years and over: data from a therapeutic drug monitoring service, 1996–2010Hum Psychopharmacol201227327728322419536
  • TsudaYSaruwatariJYasui-FurukoriNMeta-analysis: the effects of smoking on the disposition of two commonly used antipsychotic agents, olanzapine and clozapineBMJ Open201443e004216
  • SeppäläNHLeinonenEVLehtonenMLKivistöKTClozapine serum concentrations are lower in smoking than in non-smoking schizophrenic patientsPharmacol Toxicol199985524424610608488
  • NgWUchidaHIsmailZClozapine exposure and the impact of smoking and gender: a population pharmacokinetic studyTher Drug Monit200931336036619349931
  • HäggSSpigsetOMjörndalTDahlqvistREffect of caffeine on clozapine pharmacokinetics in healthy volunteersBr J Clin Pharmacol2000491596310606838
  • RaaskaKRaitasuoVLaitilaJNeuvonenPJEffect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patientsBasic Clin Pharmacol Toxicol2004941131814725610
  • PollockBGGender differences in psychotropic drug metabolismPsychopharmacol Bull19973322353419230636
  • SmithSGender differences in antipsychotic prescribingInt Rev Psychiatry201022547248421047160
  • BigosKLPollockBGStankevichBABiesRRSex differences in the pharmacokinetics and pharmacodynamics of antidepressants: an updated reviewGend Med20096452254320114004
  • RellingMVLinJSAyersGDEvansWERacial and gender differences in N-acetyltransferase, xanthine oxidase, and CYP1A2 activitiesClin Pharmacol Ther19925266436581458773
  • IqbalJSunLCaoJSmoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymesProc Natl Acad Sci U S A201311027111151112023776235
  • HaslemoTEikesethPHTanumLMoldenERefsumHThe effect of variable cigarette consumption on the interaction with clozapine and olanzapineEur J Clin Pharmacol200662121049105317089108
  • DobrinasMCornuzJOnedaBKohler SerraMPuhlMEapCBImpact of smoking, smoking cessation, and genetic polymorphisms on CYP1A2 activity and inducibilityClin Pharmacol Ther201190111712521593735
  • RütherTBobesJDe HertMEPA Guidance on tobacco dependence and strategies for smoking cessation in people with mental illnessEur Psychiatry2014292658224485753
  • MitchellDCKnightCAHockenberryJTeplanskyRHartmanTJBeverage caffeine intakes in the USFood Chem Toxicol20146313614224189158
  • McCutcheonRBeckKD’AmbrosioEAntipsychotic plasma levels in the assessment of poor treatment response in schizophreniaActa Psychiatr Scand20181371394629072776
  • Di LorenzoRSagonaMLandiGMartireLPiemonteCDel GiovaneCThe revolving door phenomenon in an Italian Acute Psychiatric Ward: a 5-year retrospective Analysis of the potential risk factorsJ Nerv Ment Dis2016204968669227227558
  • LeggeSHamshereMHayesRDReasons for discontinuing clozapine: a cohort study of patients commencing treatmentSchizophr Res20161741–311311927211516