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Original Research

Validation and Comparison of a Modified Elixhauser Index for Predicting In-Hospital Mortality in Italian Internal Medicine Wards

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Pages 443-451 | Published online: 20 May 2020

References

  • Wolff JL, Starfield B, Anderson G. Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. Arch Intern Med. 2002;162(20):2269–2276. doi:10.1001/archinte.162.20.226912418941
  • Uijen AA. van de Lisdonk EH. Multimorbidity in primary care: prevalence and trend over the last 20 years. Eur J Gen Pract. 2008;14(sup1):28–32. doi:10.1080/1381478080243609318949641
  • van den Akker MBF, Knottnerus JA. Comorbidity or multimorbidity: what’s in a name? A review of literature. Eur J Gen Practice. 1996;(2):65–70.
  • Gijsen R, Hoeymans N, Schellevis FG. Causes and consequences of comorbidity: a review. J Clin Epidemiol. 2001;54:661–674. doi:10.1016/S0895-4356(00)00363-211438406
  • Willadsen TG, Siersma V, Nicolaisdóttir DR, et al. Multimorbidity and mortality: a 15-year longitudinal registry-based nationwide Danish population study. J Comorb. 2018;8:1–9. doi:10.1177/2235042X1880406329492397
  • Nunes PBFT, Mielke GI, Thumé E. Multimorbidity and mortality in older adults: a systematic review and meta-analysis. Arch Gerontol Geriatr. 2016;67:130–138. doi:10.1016/j.archger.2016.07.00827500661
  • Menotti A, Mulder I, Nissinen A. Prevalence of morbidity and multimorbidity in elderly male populations and their impact on 10-year all-cause mortality: the FINE study (Finland, Italy, Netherlands, Elderly). J Clin Epidemiol. 2001;54:680–686. doi:10.1016/S0895-4356(00)00368-111438408
  • Ferrer A, Formiga F, Sanz H. Multimorbidity as specific disease combinations, an important predictor factor for mortality in octogenarians: the Octabaix study. Clin Interv Aging. 2017;12:223–231. doi:10.2147/CIA.S12317328184153
  • Diederichs C, Berger K, Bartels DB. The measurement of multiple chronic diseases—a systematic review on existing multimorbidity indices. J Gerontol A Biol Sci Med Sci. 2011;66:301–311. doi:10.1093/gerona/glq20821112963
  • Willadsen TG, Bebe A, Køster-Rasmussen R, et al. The role of diseases, risk factors and symptoms in the definition of multimorbidity - a systematic review. Scand J Prim Health Care. 2016;34(2):112–121. doi:10.3109/02813432.2016.115324226954365
  • Tinetti ME, Fried T. The end of the disease era. Am J Med. 2004;116(3):179–185. doi:10.1016/j.amjmed.2003.09.03114749162
  • Fabbian F, Pala M, De Giorgi A, et al. In-hospital mortality in patients with renal dysfunction admitted for myocardial infarction: the Emilia-Romagna region of Italy database of hospital admissions. Int Urol Nephrol. 2013;45(3):769–775. doi:10.1007/s11255-012-0250-922828743
  • Fabbian F, Gallerani M, Pala M, et al. In-hospital mortality for pulmonary embolism: relationship with chronic kidney disease and end-stage renal disease The hospital admission and discharge database of the Emilia Romagna region of Italy. Intern Emerg Med. 2013;8:735–740.23247683
  • Fabbian F, Gallerani M, Pala M, et al. Association between in-hospital mortality and renal dysfunction in 186,219 patients hospitalized for acute stroke in the Emilia-Romagna region of Italy. Angiology. 2014;65(10):906–910. doi:10.1177/000331971351201724277911
  • Fabbian F, De Giorgi A, López-Soto PJ, et al. Is female gender as harmful as bacteria? Analysis of hospital admissions for urinary tract infections in elderly patients. J Womens Health. 2015;24(7):587–592. doi:10.1089/jwh.2014.5140
  • Fabbian F, De Giorgi A, Manfredini F, et al. Impact of comorbidity on outcome in kidney transplant recipients: a retrospective study in Italy. Intern Emerg Med. 2016;11(6):825–832. doi:10.1007/s11739-016-1438-227003820
  • Fabbian F, De Giorgi A, Tiseo R, et al. Neoplasms and renal transplantation: impact of gender, comorbidity and age on in-hospital mortality. A retrospective study in the region Emilia-Romagna of Italy. Eur Rev Med Pharmacol Sci. 2018;22:2266–2272.29762828
  • Fabbian F, De Giorgi A, Manfredini F, et al. Impact of renal dysfunction on in-hospital mortality of patients with severe chronic obstructive pulmonary disease: a single-center Italian study. Int Urol Nephrol. 2016;48(7):1121–1127. doi:10.1007/s11255-016-1272-527020445
  • Fabbian F, Fedeli U, De Giorgi A, et al. Sex and acute oesophageal variceal bleeding-related in-hospital mortality: a 15-year retrospective study. Eur Rev Med Pharmacol Sci. 2019;23(2):811–817. doi:10.26355/eurrev_201901_1689530720189
  • Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity measures for use with administrative data. Med Care. 1998;36(1):8–27. doi:10.1097/00005650-199801000-000049431328
  • Fabbian F, De Giorgi A, Maietti E, et al. A modified Elixhauser score for predicting in-hospital mortality in internal medicine admissions. Eur J Intern Med. 2017;40:37–42. doi:10.1016/j.ejim.2017.02.00228187963
  • Quan H, Sundararajan V, Halfon P, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005;43(11):1130–1139. doi:10.1097/01.mlr.0000182534.19832.8316224307
  • Cei M, Mumoli N, Vitale J, Dentali F. A prognostic index for 1-year mortality can also predict in-hospital mortality of elderly medical patients. Intern Emerg Med. 2015;10:575–579. doi:10.1007/s11739-015-1196-625633232
  • Fabbian F, De Giorgi A, Boari B, et al. Infections and internal medicine patients: could a comorbidity score predict in-hospital mortality? Medicine (Baltimore). 2018;97(42):e12818. doi:10.1097/MD.000000000001281830334978
  • Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet. 2013;381:752–762. doi:10.1016/S0140-6736(12)62167-923395245
  • de Groot V, Beckerman H, Lankhorst GJ, Bouter LM. How to measure comorbidity. A critical review of available methods. J Clin Epidemiol. 2003;56:221–229.12725876
  • Sharabiani MT, Aylin P, Bottle A. Systematic review of comorbidity indices for administrative data. Med Care. 2012;50:1109–1118. doi:10.1097/MLR.0b013e31825f64d022929993
  • Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613–619. doi:10.1016/0895-4356(92)90133-81607900
  • Hannan EL, Kilburn H Jr, Lindsey ML, Lewis R. Clinical versus administrative data bases for CABG surgery. Does it matter? Med Care. 1992;30:892–907. doi:10.1097/00005650-199210000-000021405795
  • Kieszak SM, Flanders WD, Kosinski AS, Shipp CC, Karp H. A comparison of the Charlson comorbidity index derived from medical record data and administrative billing data. J Clin Epidemiol. 1999;52:137–142. doi:10.1016/S0895-4356(98)00154-110201654
  • Martins M, Blais R. Evaluation of comorbidity indices for inpatient mortality prediction models. J Clin Epidemiol. 2006;59:665–669. doi:10.1016/j.jclinepi.2005.11.01716765268
  • Luthi JC, Troillet N, Eisenring MC, et al. Administrative data outperformed single-day chart review for comorbidity measure. Int J Qual Health Care. 2007;19:225–231. doi:10.1093/intqhc/mzm01717599922
  • Chong WF, Ding YY, Heng BH. A comparison of comorbidities obtained from hospital administrative data and medical charts in older patients with pneumonia. BMC Health Serv Res. 2011;11:105. doi:10.1186/1472-6963-11-10521586172
  • Christensen S, Johansen MB, Christiansen CF, Jensen R, Lemeshow S. Comparison of Charlson comorbidity index with SAPS and APACHE scores for prediction of mortality following intensive care. Clin Epidemiol. 2011;3:203–211. doi:10.2147/CLEP.S2024721750629
  • Quan H, Li B, Couris CM, et al. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol. 2011;173:676–682. doi:10.1093/aje/kwq43321330339
  • Scrutinio D, Passantino A, Guida P, et al. Prognostic impact of comorbidities in hospitalized patients with acute exacerbation of chronic heart failure. Eur J Intern Med. 2016;34:63–67. doi:10.1016/j.ejim.2016.05.02027263064
  • Spannella F, Giulietti F, Cocci G, et al. Acute exacerbation of chronic obstructive pulmonary disease in oldest adults: predictors of in-hospital mortality and need for post-acute care. J Am Med Dir Assoc. 2019;20(7):893–898. doi:10.1016/j.jamda.2019.01.12530826270
  • Lash TL, Mor V, Wieland D, Ferrucci L, Satariano W, Silliman RA. Methodology, design, and analytic techniques to address measurement of comorbid disease. J Gerontol a Biol Sci Med Sci. 2007;62(3):281–285. doi:10.1093/gerona/62.3.28117389725
  • Iezzoni LI. Assessing quality using administrative data. Ann Intern Med. 1997;127:666–674. doi:10.7326/0003-4819-127-8_Part_2-199710151-000489382378
  • Karnad A, Pannelay A, Boshnakova A, Lovell AD, Cook RG. Stroke prevention in Europe: how are 11 European countries progressing toward the European Society of Cardiology (ESC) recommendations? Risk Manag Healthc Policy. 2018;11:117–125. doi:10.2147/RMHP.S16343930197544
  • Shen J, Xin W, Li Q, Gao Y, Zhang J. A grading system for the prediction of unilateral chronic subdural hematoma recurrence after initial single burr hole evacuation. Risk Manag Healthc Policy. 2019;12:179–188. doi:10.2147/RMHP.S22214431802959
  • Liu Y, Ye S, Xiao X, et al. Machine learning for tuning, selection, and ensemble of multiple risk scores for predicting Type 2 diabetes. Risk Manag Healthc Policy. 2019;12:189–198. doi:10.2147/RMHP.S22576231807099