Malignant transformation of oral lichen planus by a chronic inflammatory process. Use of topical corticosteroids to prevent this progression?

References

• Trinchieri G. Innate inflammation and cancer: Is it time for cancer prevention? F1000 Med Rep 2011;3:11.
   PubMedGoogle Scholar
• Rothwell PM, Fowkes FG, Belch JF, Ogawa H, Warlow CP, Meade TW. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011;377:31–41.
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646–74.
   PubMed Web of Science ®Google Scholar
• Feller L, Altini M, Lemmer J. Inflammation in the context of oral cancer. Oral Oncol 2013;49:887–92.
   PubMed Web of Science ®Google Scholar
• Liu Y, Messadi DV, Wu H, Hu S. Oral lichen planus is a unique disease model for studying chronic inflammation and oral cancer. Med Hypotheses 2010;75:492–4.
   PubMed Web of Science ®Google Scholar
• Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K. Current controversies in oral lichen planus: report of an international consensus meeting. Part 1.Viral infections and etiopathogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;100:40–51.
   PubMed Web of Science ®Google Scholar
• Nibali L, Fedele S, D’Aiuto F, Donos N. Interleukin-6 in oral diseases: a review. Oral Dis 2012;18:236–43.
   PubMed Web of Science ®Google Scholar
• Roopashree MR, Gondhalekar RV, Shashikanth MC, George J, Thippeswamy SH, Shukla A. Pathogenesis of oral lichen planus-a review. J Oral Pathol Med 2010;39:729–34.
   PubMed Web of Science ®Google Scholar
• Carrozzo M, Uboldi de Capei M, Dametto E, Fasano ME, Arduino P, Broccoletti R, et al. Tumor necrosis factor-alpha and interferon-gamma polymorphisms contribute to susceptibility to oral lichen planus. J Invest Dermatol 2004;122:87–94.
   PubMed Web of Science ®Google Scholar
• Marder MZ, Deesen KC. Transformation of oral lichen planus to squamous cell carcinoma: a literature review and report of case. J Am Dent Assoc 1982;105:55–60.
   PubMed Web of Science ®Google Scholar
• Krutchkoff DJ, Cutler L, Laskowski S. Oral lichen planus: the evidence regarding potential malignant transformation. J Oral Pathol 1978;7:1–7.
   PubMedGoogle Scholar
• Gonzalez-Moles MA, Scully C, Gil-Montoya JA. Oral lichen planus: controversies surrounding malignant transformation. Oral Dis 2008;14:229–43.
   PubMed Web of Science ®Google Scholar
• Bermejo-Fenoll A, Sánchez-Siles M, López-Jornet P, Camacho-Alonso F, Salazar-Sánchez N. A retrospective clinicopathological study of 550 patients with oral lichen planus in south-eastern Spain. J Oral Pathol Med 2010;39:491–6.
   PubMed Web of Science ®Google Scholar
• Van der Meij EH, van der Waal I. Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications. J Oral Pathol Med 2003;32:507–12.
   PubMed Web of Science ®Google Scholar
• van der Meij EH, Schepman KP, Smeele LE, van der Wal JE, Bezemer PD, van der Waal I. A review of the recent literature regarding malignant transformation of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;88:307–10.
   PubMedGoogle Scholar
• Kramer IR, Lucas RB, Pindborg JJ, Sobin LH. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg Oral Med Oral Pathol 1978;46:518–39.
   PubMedGoogle Scholar
• Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med 2007;36:575–80.
   PubMed Web of Science ®Google Scholar
• Bombeccari GP, Guzzi G, Tettamanti M, Giannì AB, Baj A, Pallotti F, et al. Oral lichen planus and malignant transformation: a longitudinal cohort study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112:328–34.
   PubMedGoogle Scholar
• Fang M, Zhang W, Chen Y, He Z. Malignant transformation of oral lichen planus: a retrospective study of 23 cases. Quintessence Int 2009;40:235–42.
   PubMedGoogle Scholar
• Lind PO, Strømme Koppang H, Aas E. Malignant transformation in oral lichen planus. Int J Oral Surg 1985;14:509–16.
   PubMedGoogle Scholar
• Kaplan B, Barnes L. Oral lichenplanus and squamous carcinoma. Case report and update of the literature. Arch Otolaryngol 1985;111:543–7.
   PubMedGoogle Scholar
• Silverman S Jr, Gorsky M, Lozada-Nur F, Giannotti K. A prospective study of findings and management in 214 patients with oral lichen planus. Oral Surg Oral Med Oral Pathol 1991;72:665–70.
   PubMedGoogle Scholar
• Lo Muzio L, Mignogna MD, Favia G, Procaccini M, Testa NF, Bucci E. The possible association between oral lichen planus and oral squamous cell carcinoma: a clinical evaluation on 14 cases and a review of the literature. Oral Oncol 1998;34:239–46.
   PubMedGoogle Scholar
• Payeras MR, Cherubini K, Figueiredo MA, Salum FG. Oral lichen planus: focus on etiopathogenesis. Arch Oral Biol 2013;58:1057–69.
   PubMed Web of Science ®Google Scholar
• Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860–7.
   PubMed Web of Science ®Google Scholar
• Mignogna MD, Fedele S, Lo Russo L, Lo Muzio L, Bucci E. Immune activation and chronic inflammation as the cause of malignancy in oral lichen planus: is there any evidence? Oral Oncol 2004;40:120–30.
   PubMed Web of Science ®Google Scholar
• Balkwill FR, Mantovani A. Cancer-related inflammation: common themes and therapeutic opportunities. Semin Cancer Biol 2012;22:33–40.
   PubMed Web of Science ®Google Scholar
• Gallego L, Junquera L, Calvo N, Fuente E, Rosado P. Bilateral carcinoma in situ of Wharton’s duct after chronic obstructive sialadenitis: inflammation as the cause of malignancy? Ann Otol Rhinol Laryngol 2012;121:296–300.
   PubMedGoogle Scholar
• Mueller MM. Inflammation in epithelial skin tumours: old stories and new ideas. Eur J Cancer 2006;42:735–44.
   PubMed Web of Science ®Google Scholar
• Merry R, Belfield L, McArdle P, McLennan A, Crean S, Foey A. Oral health and pathology: a macrophage account. Br J Oral Maxillofac Surg 2012;50:2–7.
   PubMed Web of Science ®Google Scholar
• Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3:23–35.
   PubMed Web of Science ®Google Scholar
• Li J, Farthing PM, Thornhill MH. Oral and skin keratinocytes are stimulated to secrete monocyte chemoattractant protein-1 by tumour necrosis factor-alpha and interferon-gamma. J Oral Pathol Med 2000;29:438–44.
   PubMedGoogle Scholar
• Sica A, Allavena P, Mantovani A. Cancer related inflammation: the macrophage connection. Cancer Lett 2008;267:204–15.
   PubMed Web of Science ®Google Scholar
• Sharma R, Sircar K, Singh S, Rastogi V. Role of mast cells in pathogenesis of oral lichen planus. J Oral Maxillofac Pathol 2011;15:267–71.
   PubMedGoogle Scholar
• Jontell M, Hansson HA, Nygren H. Mast cells in oral lichen planus. J Oral Pathol 1986;15:273–5.
   PubMedGoogle Scholar
• Coussens LM, Raymond WW, Bergers G, Laig-Webster M, Behrendtsen O, Werb Z, et al. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 1999;13:1382–97.
   PubMed Web of Science ®Google Scholar
• Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145–73.
   PubMed Web of Science ®Google Scholar
• O’Byrne KJ, Dalgleish AG. Chronic immune activation and inflammation as the-cause of malignancy. Br J Cancer 2001;85:473–83.
   PubMed Web of Science ®Google Scholar
• Simark-Mattsson C, Bergenholtz G, Jontell M, Eklund C, Seymour GJ, Sugerman PB, et al. Distribution of interleukin-2, -4, -10, tumour necrosis factor-alpha and transforming growth factor-beta mRNAs in oral lichen planus. Arch Oral Biol 1999;44:499–507.
   PubMed Web of Science ®Google Scholar
• Kishimoto T, Akira S, Narazaki M, Taga T. Interleukin-6 family of cytokines and gp130. Blood 1995;86:1243–54.
   PubMed Web of Science ®Google Scholar
• Moreau P, Harousseau JL, Wijdenes J, Morineau N, Milpied N, Bataille R. A combination of anti-interleukin 6 murine monoclonal antibody with dexamethasone and highdosemelphalan induces high complete response rates in advanced multiple myeloma. Br J Haematol 2000;109:661–4.
   PubMed Web of Science ®Google Scholar
• Park JY, Pillinger MH. Interleukin-6 in the pathogenesis of rheumatoid arthritis. Bull NYU Hosp Jt Dis 2007;65:S4–10.
   PubMedGoogle Scholar
• Packard RR, Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem 2008;54:24–38.
   PubMed Web of Science ®Google Scholar
• Nishimoto N. Interleukin-6 as a therapeutic target in candidate inflammatory diseases. Clin Pharmacol Ther 2010;87:483–7.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, et al. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population. Cytokine 2008;41:144–9.
   PubMed Web of Science ®Google Scholar
• Gu GM, Martin MD, Darveau RP, Truelove E, Epstein J. Oral and serum IL-6 levels in oral lichen planus patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:673–8.
   PubMedGoogle Scholar
• Bigbee WL, Grandis JR, Siegfried JM. Multiple cytokine and growth factor serum biomarkers predict therapeutic response and survival in advanced-stage head and neck cancer patients. Clin Cancer Res 2007;13:3107–8.
   PubMedGoogle Scholar
• Rhodus NL, Cheng B, Bowles W, Myers S, Miller L, Ondrey F. Proinflammatory cytokine levels in saliva before and after treatment of (erosive) oral lichen planus with dexamethasone. Oral Dis 2006;12:112–16.
   PubMedGoogle Scholar
• Sun A, Chia JS, Chang YF, Chiang CP. Serum Interleukin-6 level is a useful marker in evaluating therapeutic effects of levamisole and Chinese medicinal herbs on patients with oral lichen planus. J Oral Pathol Med 2002;31:196–203.
   PubMedGoogle Scholar
• Gasche JA, Hoffmann J, Boland CR, Goel A. Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells. Int J Cancer 2011;129:1053–63.
   PubMed Web of Science ®Google Scholar
• Thongprasom K, Carrozzo M, Furness S, Lodi G. Interventions for treating oral lichen planus. Cochrane Database Syst Rev 2011:CD001168.
   PubMedGoogle Scholar
• Lodi G, Carrozzo M, Furness S, Thongprasom K. Interventions for treating oral lichen planus: a systematic review. Br J Dermatol 2012;166:938–47.
   PubMedGoogle Scholar
• Carbone M, Goss E, Carrozo M, Castellano S, Conrrotto D, Broccoletti R, et al. Systemic and topical corticosteroid treatment of oral lichen planus. J Oral Pathol Med 2003;32:323–9.
   PubMedGoogle Scholar
• González-García A, Diniz-Freitas M, Gándara-Vila P, Blanco-Carrión A, Garcia-Garcia A, Gándara-Rey JM. Triamcinolone acetonide mouth rinses for treatment of erosive oral lichen planus; efficacy and risk of oral fungal over-infection. Oral Dis 2006;2:559–65.
   Google Scholar
• Eisen D. The clinical features, malignant potential, and systemic associations of oral lichen planus: a study of 723 patients. J Am Acad Dermatol 2002;46:207–14.
   PubMed Web of Science ®Google Scholar
• González-Moles MA. The use of topical corticoids in oral pathology. Med Oral Patol Oral Cir Bucal 2010;15:827–31.
   Google Scholar
• Lozada-Nur F, Miranda C. Oral lichen planus: topical and systemic therapy. Semin Cutan Med Surg 1997;16:295–300.
   PubMedGoogle Scholar
• Varoni EM, Molteni A, Sardella A, Carrassi A, Di Candia D, Gigli F, et al. Pharmacokinetics study about topical clobetasol on oral mucosa. J Oral Pathol Med 2012;41:255–60.
   PubMedGoogle Scholar
• Sugerman PB, Savage NW, Walsh LJ, Zhao ZZ, Zhou XJ, Khan A, et al. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med 2002;13:350–65.
   PubMedGoogle Scholar
• Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K. Current controversies in oral lichen planus: report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;100:164–78.
   PubMed Web of Science ®Google Scholar
• Gandolfo S, Richiardi L, Carrozzo M, Broccoletti R, Carbone M, Pagano M, et al. Risk of oral squamous cell carcinoma in 402 patients with oral lichen planus: a follow-up study in an Italian population. Oral Oncol 2004;40:77–83.
   PubMed Web of Science ®Google Scholar
• Gándara Rey JM, Diniz Freitas M, Gándara Vila P, Blanco Carrión A, Suárez Peñaranda JM, García García A. Malignant transformation of oral lichen planus in lingual location: report of a case. Oral Oncol Extra 2004;40:1–4.
   Google Scholar
• Epstein JB, Wan LS, Gorsky M, Zhang L. Oral lichen planus: progress in understanding its malignant potencial and the implications for clinical management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;96:32–7.
   PubMedGoogle Scholar
• Snyderman R, Cianciolo GJ. Inmunosuppressive activity in the retroviral envelope protein P15E and its posible relationship to neoplasia. Immunol Today 1984;5:240–4.
   PubMedGoogle Scholar
• Rutledge BJ, Rayburn H, Rosenberg R, North RJ, Gladue RP, Corless CL, et al. High level monocyte chemoattractant protein-1 expression in transgenic mice increases their susceptibility to intracellular pathogens. J Immunol 1995;155:4838–43.
   PubMed Web of Science ®Google Scholar
• Cha JD, Kim HJ, Cha IH. Genetic alterations in oral squamous cell carcinoma progression detected by combining array-based comparative genomic hybridization and multiplex ligation-dependent probe amplification. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111:594–607.
   PubMed Web of Science ®Google Scholar
• Noutomi Y, Oga A, Uchida K, Okafuji M, Ita M, Kawauchi S, et al. Comparative genomic hybridization reveals genetic progression of oral squamous cell carcinoma from dysplasia via two different tumourigenic pathways. J Pathol 2006;210:67–74.
   PubMedGoogle Scholar