314
Views
5
CrossRef citations to date
0
Altmetric
Original Article

The effects of periodontal therapy on serum and salivary leptin levels in chronic periodontitis patients with normal body mass index

, , , , , , & show all
Pages 633-641 | Received 01 Feb 2015, Accepted 09 Mar 2015, Published online: 08 Apr 2015

References

  • Savage A, Eaton KA, Moles DR, Eaton KA, Moles DR, Needleman I. A systematic review of definitions of periodontitis and methods that have been used to identify this disease. J Clin Periodontol 2009;36:458–67.
  • Genco RJ. Host responses in periodontal diseases: Current concepts. J Periodontol 1992;63:338–55.
  • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425–32.
  • Faggioni R, Fantuzzi G, Fuller J. IL-I beta mediates leptin induction during inflammation. Am J Physiol 1998;274:204–8.
  • La Cava A, Matarese G. The weight of leptin in immunity. Nat Rev Immunol 2004;4:371–9.
  • Yilmaz Z, Ilcol YO, Ulus IH. Endotoxin increases plasma leptin and ghrelin levels in dogs. Crit Care Med 2008;36:828–33.
  • Wajchenberg BL, Nery M, Cunha MR, Silva ME. Adipose tissue at the crossroads in the development of the metabolic syndrome, inflammation and atherosclerosis. Arq Bras Endocrinol Metabol 2009;53:145–50.
  • Maffei M, Fei H, Lee GH. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus. Proc Natl Acad Sci USA 1995;92:6957–60.
  • Masuzaki H, Ogawa Y, Sagawa N. Nonadipose tissue production of leptin: Leptin as a novel placenta-derived hormone in humans. Nat Med 1995;3:1029–33.
  • Bado A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, et al. The stomach is a source of leptin. Nature 1998;394:790–3.
  • Sanna V, Giacomo AD, Cava AL, Lechler RI, Fontana S, Zappacosta S, et al. Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses. J Clin Invest 2003;111:241–50.
  • Gordeladze JO, Drevon CA, Syversen U. Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis and mineralization: impact on differentiation markers, apoptosis and osteoclastic signaling. J Cell Biochem 2002;85:825–36.
  • De Matteis R, Puxeddu R, Riva A, Cinti S. Intralobular ducts of human major salivary glands contain leptin and its receptor. J Anat 2002;201:363–70.
  • Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 1998;393:684–8.
  • Johnson RB, Serio FG. Leptin within healthy and diseased human gingiva. J Periodontol 2001;72:1254–7.
  • Karthikeyan BV, Pradeep AR. Gingival crevicular fluid and serum leptin: Their relationship to periodontal health and disease. J Clin Periodontol 2007;34:467–72.
  • Shimada Y, Komatsu Y, Ikezawa-Suzuki I, Tai H, Sugita N, Yoshie H. The effect of periodontal treatment on serum leptin, interleukin-6, and C - reactive protein. J Periodontol 2010;81:1118–23.
  • Zimmermann GS, Bastos MF, Dias Gonçalves TE, Chambrone L, Duarte PM. Local and circulating levels of adipocytokines in obese and normal weight individuals with chronic periodontitis. J Periodontol 2013;84:624–33.
  • Gundala R, Chava VK, Ramalingham K. Association of leptin in periodontitis and acute myocardial infarction. J Periodontol 2014;85:917–24.
  • Söderberg S, Ahrén B, Jansson JH, Johnson O, Hallmans G, Asplund K, et al. Leptin is associated with increased risk of myocardial infarction. J Intern Med 1999;246:409–18.
  • Leyva F, Anker SD, Egerer K, Stevenson JC, Kox WJ, Coats AJ. Hyperleptinaemia in chronic heart failure. Relationships with insulin. Eur Heart J 1998;19:1547–51.
  • Wallace AM, McMahon AD, Packard CJ, Kelly A, Shepherd J, Gaw A, et al. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 2001;104:3052–6.
  • Purwar P, Khan MA, Mahdi AA, Pandey S, Singh B, Dixit J, et al. Salivary and serum leptin concentrations in patients with chronic periodontitis. J Periodontol 2014;24:1–10.
  • WHO Expert Consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004;363:157–63.
  • Williams JR. The Declaration of Helsinki and public health. Bull World Health Organ 2008;86:650–2.
  • Dudala SR, Arlappa N. An updated Prasad’s socio economic status classification. Int J Res Dev Health 2013;1:26–8.
  • Silness J, Loe H. Periodontal disease in pregnancy. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121–35.
  • Loe H, Silness J. Periodontal disease in pregnancy. Prevalence and severity. Acta Odontol Scand 1963;21:533–51.
  • Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1–6.
  • Miller CS, Joseph DF, John TMB. Current developments in salivary diagnostics. Biomark Med 2010;4:171–89.
  • Tonetti MS, Claffey N, European Workshop in Periodontology group C. Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research. Group C consensus report of the 5th European Workshop in Periodontology. J Clin Periodontol 2005;32:210–13.
  • Giannobile WV, Beikler T, Kinney JS, Ramseier CA, Morelli T, Wong DT. Saliva as a diagnostic tool for periodontal disease: current state and future directions. Periodontol 2000 2009;50:52–64.
  • Chiappin S, Antonelli G, Gatti R, De Palo EF. Saliva specimen: A new laboratory tool for diagnostic and basic investigation. Clin Chim Acta 2007;383:30–40.
  • Graves DT. The potential role of chemokines and inflammatory cytokines in periodontal disease progression. Clin Infect Dis 1999;28:482–90.
  • Page RC. The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodontal Res 1991;26:230–42.
  • Beck J, Garcia R, Heiss G, Vokonas PS, Offenbacher S. Periodontal disease and cardiovascular disease. J Periodontol 1996;67:1123–37.
  • Arnalich F, López J, Codoceo R, Jimnez M, Madero R, Montiel C. Relationship of plasma leptin to plasma cytokines and human survivalin sepsis and septic shock. J Infect Dis 1999;80:908–11.
  • Koh KK, Park SM, Quon MJ. Leptin and cardiovascular disease: Response to therapeutic interventions. Circulation 2008;24:3238–49.
  • Nakata M, Yada T, Soejima N, Soejima N, Maruyama I. Leptin promotes aggregation of human platelets via the long form of its receptor. Diabetes 1999;48:426–9.
  • Kang SM, Kwon HM, Hong BK, Kim D, Kim IJ, Choi EY, et al. Expression of leptin receptor (Ob-R) in human atherosclerotic lesions: Potential role in intimal neovascularization. Yonsei Med J 2000;41:68–75.
  • Beltowski J, Wojcicka G, Jamroz A. Leptin decreases plasma araoxonase 1 (PON1) activity and induces oxidative stress: the possible novel mechanism for proatherogenic effect of chronic hyperleptinemia. Atherosclerosis 2003;170:21–9.
  • Parhami F, Tintut Y, Ballard A. Leptin enhances the calcification of vascular cells: artery wall as a target of leptin. Circ Res 2001;88:954–60.
  • Randeva H, Karteris E, Lewandowski KC, Sailesh S, O’Hare P, Hillhouse EW. Circadian rhythmicity of salivary leptin in healthy subjects. Mol Genet Metab 2003;78:229–35.
  • Thomas T, Gori F, Khosla S, Jensen MD, Burguera B, Riggs BL. Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 1999;140:1630–8.
  • Loffreda S, Yang SQ, Lin HZ, Karp CL, Brengman ML, Wang DJ, et al. Leptin regulates proinflammatory immune responses. FASEB J 1998;12:57–65.
  • Zhao Y, Sun R, You L, Gao C, Tian Z. Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines. Biochem Biophys Res Commun 2003;300:247–52.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.