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INNER EAR

Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear

, MD, , , &
Pages 1340-1350 | Received 18 Dec 2008, Published online: 18 Nov 2009

References

  • Jiang H, Talaska AE, Schacht J, Sha S-H. Oxidative imbalance in the aging inner ear. Neurobiol Aging 2007; 28: 1605–12
  • Kuro-o M, Matumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, et al. Mutation of the klotho gene leads to a syndrome resembling aging. Nature 1997; 390: 45–51
  • Nabeshima Y-I. Toward a better understanding of klotho. Sci Aging Knowl Environ 2006; 8: 11
  • Kamemori M, Ohyama Y, Kurabayashi M, Takahashi K, Nagai R, Furuya N. Expression of klotho protein in the inner ear. Hear Res 2002; 171: 103–10
  • Takumida M, Kubo N, Ohtani M, Suzuka Y, Anniko M. Transient receptor potential channels in the inner ear: presence of transient receptor potential channel superfamily 1 and 4 in the guinea pig inner ear. Acta Otolaryngol 2005; 125: 929–34
  • Ishibashi T, Takumida M, Akagi N, Hirakawa K, Anniko M. Expression of transient receptor potential vanilloids 1, 2, 3 and 4 in the mouse inner ear. Acta Otolaryngol 2008; 128: 1286–93
  • Wangemann P, Nakaya K, Wu T, Maganti RJ, Itza EM, Sanneman JD, et al. Loss of cochlear HCO3− secretion causes deafness via endolymphatic acidification and inhibition of Ca2 + reabsorption in a Pendred syndrome mouse model. Am J Physiol Renal Physiol 2007; 292: F1345–53
  • Nakaya K, Harbidge DG, Wangemann P, Schultz BD, Green ED, Wall SM, et al. Lack of pendrin HCO3− transport elevates vestibular endolymphatic [Ca2 +] by inhibition of acid-sensitive TRPV5 and TRPV6 channels. Am J Physiol Renal Physiol 2007; 292: F1314–21
  • Shih P-H, Yen G-C. Differential expressions of antioxidant status in aging rats: the role of transcriptional factor Nrf2 and MAPK signaling pathway. Biogerontology 2007; 8: 71–80
  • Schoeber JPH, Hoenderop JGJ, Bindels RJM. Concerted action of associated proteins in the regulation of TRPV5 and TRPV6. Biochem Soc Trans 2007; 35(Pt 1)115–19
  • Chang Q, Hoefs S, Kemp W, Topala CN, Bindels RJ, Hoenderop JG. The β-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. Science 2005; 310: 490–3
  • Van Abel M, Huybers S, Hoenderop JGJ, van de Kemp AWCM, van Leeuwen JPTM, Bindels RJM. Age-dependent alterations in Ca2 + homeostasis: role of TRPV5 and TRPV6. Am J Physiol Renal Physiol 2006; 291: F1177–83
  • Offner FF, Dallos P, Cheatham MA. Positive endocochlear potential: mechanism of production by marginal cells of stria vascularis. Hear Res 1987; 29: 117–24
  • Nilium B, Owsianik G, Voets T, Peters JA. Transient receptor potential cation channels in disease. Physiol Rev 2007; 87: 165–217
  • Yamoah EN, Lumpkin EA, Dumont RA, Smith PJ, Hudspeth AJ, Gillespie PG. Plasma membrane Ca2 +-ATPase extrudes Ca2 + from hair cell stereocilia. J Neurosci 1998; 18: 610–24
  • Benser ME, Marquis RE, Hudspeth AJ. Rapid, active hair bundle movements in hair cells from the bullfrog's sacculus. J Neurosci 1996; 16: 5629–43
  • Crouch JJ, Schulte BA. Expression of plasma membrane Ca-ATPase in the adult and developing gerbil cochlea. Hear Res 1995; 92: 112–19
  • Takumida M, Zhang DM. Electron probe X-ray microanalysis of otoconia in guinea pig inner ear: a comparison between young and old animals. Acta Otolaryngol 1997; 117: 529–37

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