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Original Article

Aminoglycoside Ototoxicity: Influence of Dosage Regimen on Drug Uptake and Correlation between Membrane Binding and some Clinical Features

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Pages 511-515 | Published online: 08 Jul 2009

References

  • Tran B A, Huy P, Manuel C, Meulemans A, Sterkers O, Amiel C. Pharmacokinetics of gentamicin in perilymph and endolymph of the rat as determined by radioimmunoassay. J Infect Dis 1981; 143: 476–86
  • Tran B A, Huy P, Meulemans A, Wassef M, Manuel C, Sterkers O, Amiel C. Gentamicin persistence in rat endolymph and perilymph after two-day constant infusion. Antimicrob Agents Chemother 1983; 23: 344–46
  • Tran B A, Huy P, Bernard P, Schacht J. Kinetics of gentamicin uptake and release in the rat. Comparison of inner ear tissues and fluids with other organs. J Clin Invest 1986; 77: 1492–1500
  • Tran B A, Huy P, Deffrennes D. Aminoglycoside binding sites in the inner ear of guinea pig. Abstracts XXIV° I.E.B. Meeting., Nijmegen, Sept, 1987
  • Schacht J, Weiner N. Aminoglycoside-induced hearing loss: a molecular hypothesis. ORL 1986; 48: 116–23
  • Meulemans A, Manuel C, Tran B A, Huy P. Radioimmunoassay of gentamicin in microliter and nanoliter samples of biological fluids. Chemotherapy 1981; 27: 29–33
  • Lowry O H, Rosebrough N H, Fair A L, Randall R J. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193: 265–75
  • De Lean A, Munson P J, Rodbard D. Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. Am J Physiol 1978; 235((2))E97–E102
  • Pechere J C, Bernard P. Gentamicin ototoxicity can be avoided if a new therapeutic regimen is used. Abstracts XXIV Interscience Conference on Antimicrobial Agents and Chemotherapy. 1984, 93
  • Brummett R E, Fox K E. Studies of aminoglycoside ototoxicity in animal models. The aminoglycosides: microbiology, clinical use and toxicology. Marcel Dekker, Inc, New York 1982; 419–51
  • Davies R P, Brummett R E, Bendrick T W, Himes D L. Dissociation of maximum concentrations of kanamycin in plasma and perilymph from ototoxic effect. J Antimicrob Chemother 1984; 14: 291–302
  • Powell S H, Thompson W L, Luthe M A, et al. Once daily vs continuous aminoglycoside dosing: Efficacy and toxicity in animals and clinical studies of gentamicin, netilmicin and tobramycin. J Infect Dis 1983; 147: 918–32
  • Lerner S A, Matz G J, Hawkins J E. Aminoglycoside ototoxicity. Little, Brown & Co, Boston 1981
  • Tange R A, Conijn E AG, van Zeyl L PG, Huizing E H. Pattern of gentamicin-induced cochlear degeneration in guinea pig. Arch Oto-Rhino-Lar 1982; 236: 173–84

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