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Original Article

The Anti-motion Sickness Mechanism of Ginger: A Comparative Study with Placebo and Dimenhydrinate

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Pages 168-174 | Published online: 08 Jul 2009

References

  • Holtmann S, Seifert J, Scherer H. Ursachen und Behandlung der Seekrankheit. Laryngol Rhinol Otol (Stuttg) 1987; 66: 99–103
  • Lucas V S, Laszlo L. Delta-9-tetrahydrocannabinol for refractory vomiting induced by cancer chemotherapy. J Am Med Assoc 1980; 243: 1241–3
  • Mowrey D B, Clayson D E. Motion sickness, ginger and psychophysics. Lancet 1982; i: 655–7
  • Grøntved A, Brask T, Kambskard J, Hentzer E. Ginger root against seasickness. A controlled trial on the open sea. Acta Otolaryngol (Stockh) 1988; 105: 45–9
  • Brandt T, Dichgans J, Wagner W. Drug effectiveness on experimental optokinetic and vestibular motion sickness. Aerospace Med 1974; 45: 1291–7
  • Wortmann A, Berg M, Haid T. A new computer analysis of the caloric test. Acta Otolaryngol (Stockh) 1984; 406(Suppl)174–7
  • Grøntved A, Hentzer E. Vertigo-reducing effect of ginger root. ORL 1986; 48: 282–6
  • Collins W E, Schroeder D J, Elam G W. Effects of d-amphetamine and of secobarbital on optokinetic and rotation induced nystagmus. Aviat Space Environ Med 1975; 46(4)357–66
  • Pyykko U I, Schalén L, Matsuoka J. Transdermally administered scopolamine and dimenhydrinate. II. Effect on different types of nystagmus. Acta Otolaryngol (Stockh) 1985; 99: 597–604
  • Scherer H, Schmidtmayer E, Hirche H. Die Wirkung von Bencyclan, Flunarizin und Naftidro-furyl auf den Nystagmus eines kalorischen Dauerreizes. Laryngol Rhinol Otol (Stuttg) 1978; 57: 773–8
  • Vesterhauge S, Peitersen E. The effects of some drugs on the caloric induced nystagmus. Adv Otorhinolaryngol 1979; 25: 173–7
  • Jaju B P, Wang S C. Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: a search for the locus of their anti-motion sickness action. J Pharmacol Exp Ther 1971; 176: 718–24
  • Collins W E, Schroeder D J, Elam G W. A comparison of some effects of three anti-motion sickness drugs on nystagmic responses to angular responses and to optokinetic stimuli. Aviat Space Environ Med 1982; 53: 1182–9
  • Kohl R L, Lewis M R. Mechanisms underlying the anti-motion sickness effects of psychostimulants. Aviat Space Environ Med 1987; 58: 1215–8
  • Pyykko U I, Padovan S, Lyttkens M, Magnusson M, Schalén L. Effect of Lidocaine and Tocainide on vertigo, nausea, nystagmus and voluntary eye movement. The vestibular system: Neurophysiologic and clinical research, M D Graham, J L Kemink. Raven Press, New York 1987
  • Pfaltz C R, Ildiz F. The optokinetic test: interaction of the vestibular and optokinetic system in normal subjects and patients with vestibular disorders. Arch Otorhinolaryngol 1982; 234: 21–31
  • Yamahara J, Miki K, Chisaka T, Sawada T, Fujimura H, Tomimatsu T, Nakano K, Nohora T. Cholagogic effect of ginger and its active constituents. J Ethnopharm 1985; 13: 217–25
  • Suekawa M, Ishige A, Yuasa K, Sudo K, Aburada M, Hosoya E. Pharmacological studies on ginger. I. Pharmacological actions of pungent constituents (6)-gingerol and (6)-shogaol. J Pharm Dyn 1984; 7: 836–48

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