488
Views
2
CrossRef citations to date
0
Altmetric
INNER EAR

Type I hair cell regeneration induced by Math1 gene transfer following neomycin ototoxicity in rat vestibular sensory epithelium

, , , , , , , , & show all
Pages 819-828 | Received 06 Jan 2012, Accepted 28 Feb 2012, Published online: 05 Jun 2012

References

  • Baird RA, Steyger PS, Schuff NR. Mitotic and nonmitotic hair cell regeneration in the bullfrog vestibular otolith organs. Ann NY Acad Sci 1996;781:59–70.
  • Stone JS, Oesterle EC, Rubel EW. Recent insights into regeneration of auditory and vestibular hair cells. Curr Opin Neurol 1998;11:17–24.
  • Forge A, Li L, Corwin JT, Nevill G. Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science 1993;259:1616–19.
  • Staecker H, Praetorius M, Baker K, Brough DE. Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer. Otol Neurotol 2007;28:223–31.
  • Davies S, Forge A. Preparation of the mammalian organ of Corti for scanning electron microscopy. J Microsc 1987;147:89–101.
  • Lyford-Pike S, Vogelheim C, Chu E, Della Santina CC, Carey JP. Gentamicin is primarily localized in vestibular type I hair cells after intratympanic administration. J Assoc Res Otolaryngol 2007;8:497–508.
  • Guthrie OW. Aminoglycoside induced ototoxicity. Toxicology 2008;249:91–6.
  • Forge A, Schacht J. Aminoglycoside antibiotics. Audiol Neurootol 2000;5:3–22.
  • Wu WJ, Sha SH, McLaren JD, Kawamoto K, Raphael Y, Schacht J. Aminoglycoside ototoxicity in adult CBA, C57BL and BALB mice and the Sprague-Dawley rat. Hear Res 2001;158:165–78.
  • Carvalho GJ, Lalwani AK. The effect of cochleostomy and intracochlear infusion on auditory brain stem response threshold in the guinea pig. Am J Otol 1999;20:87–90.
  • Jero J, Tseng CJ, Mhatre AN, Lalwani AK. A surgical approach appropriate for targeted cochlear gene therapy in the mouse. Hear Res 2001;151:106–14.
  • Minoda R, Izumikawa M, Kawamoto K, Raphael Y. Strategies for replacing lost cochlear hair cells. Neuroreport 2004;15:1089–92.
  • Izumikawa M, Minoda R, Kawamoto K, Abrashkin KA, Swiderski DL, Dolan DF, Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nat Med 2005;11:271–6.
  • Kawamoto K, Oh SH, Kanzaki S, Brown N, Raphael Y. The functional and structural outcome of inner ear gene transfer via the vestibular and cochlear fluids in mice. Mol Ther 2001;4:575–85.
  • Praetorius M, Knipper M, Schick B, Tan J, Limberger A, Carnicero E, A novel vestibular approach for gene transfer into the inner ear. Audiol Neurootol 2002;7:324–34.
  • Stone JS, Rubel EW. Temporal, spatial, and morphologic features of hair cell regeneration in the avian basilar papilla. J Comp Neurol 2000;417:1–16.
  • Meiteles LZ, Raphael Y. Scar formation in the vestibular sensory epithelium after aminoglycoside toxicity. Hear Res 1994;79:26–38.
  • White PM, Doetzlhofer A, Lee YS, Groves AK, Segil N. Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature 2006;441:984–7.
  • Li L, Forge A. Morphological evidence for supporting cell to hair cell conversion in the mammalian utricular macula. Int J Dev Neurosci 1997;15:433–46.
  • Lue JH, Day AS, Cheng PW, Young YH. Vestibular evoked myogenic potentials are heavily dependent on type I hair cell activity of the saccular macula in guinea pigs. Audiol Neurootol 2009;14:59–66.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.