Effect of Low Mg²⁺ and Bicuculline on Cell Survival in Hippocampal Slice Cultures

REFERENCES

• Armand, V., Rundfeldt, C., & Heinemann, U. (1997). Effects of AWD 140–190 on stimulus-induced field potentials and on different patterns of epileptiform activity induced by low calcium or low magnesium in rat entorhinal cortex hippocampal slices. Epilepsy Research, 29(1), 59–69.
   PubMed Web of Science ®Google Scholar
• Bernasconi, N., Bernasconi, A., Caramanos, Z., Antel, S. B., Andermann, F., & Arnold, D. L. (2003). Mesial temporal damage in temporal lobe epilepsy: A volumetric MRI study of the hippocampus, amygdala and parahippocampal region. Brain, 126(2), 462–469.
   PubMed Web of Science ®Google Scholar
• Blümcke, I., Beck, H., Lie, A. A., & Wiestler, O. D. (1999). Molecular neuropathology of human mesial temporal lobe epilepsy. Epilepsy Research, 36(2–3), 205–223.
   Web of Science ®Google Scholar
• Bruce, A. J., Sakhi, S., Schreiber, S. S., & Baudry, M. (1995). Development of kainic acid and N-methyl-D-aspartic acid toxicity in organotypic hippocampal cultures. Experimental Neurology, 132(2), 209–219.
   PubMed Web of Science ®Google Scholar
• Deshpande, L. S., Lou, J. K., Mian, A., Blair, R. E., Sombati, S., Attkisson, E., (2008). Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: Role of NMDA receptor activation and NMDA dependent calcium entry. European Journal of Pharmacology, 583(1), 73–83.
   PubMed Web of Science ®Google Scholar
• Devi, P. U., Manocha, A., & Vohora, D. (2008). Seizures, antiepileptics, antioxidants and oxidative stress: An insight for researchers. Expert Opinion on Pharmacotherapy, 9(18), 3169–3177.
   PubMed Web of Science ®Google Scholar
• Frantseva, M. V., Velazquez, J. L., Hwang, P. A., & Carlen, P. L. (2000). Free radical production correlates with cell death in an in vitro model of epilepsy. European Journal of Neuroscience, 12(4), 1431–1439.
   PubMed Web of Science ®Google Scholar
• Gloveli, T., Albrecht, D., & Heinemann, U. (1995). Properties of low Mg2+ induced epileptiform activity in rat hippocampal and entorhinal cortex slices during adolescence. Developmental Brain Research, 87(2), 145–152.
   PubMedGoogle Scholar
• Gutiérrez, R., Armand, V., Schuchmann, S., & Heinemann, U. (1999). Epileptiform activity induced by low Mg2+ in cultured rat hippocampal slices. Brain Research, 815(2), 294–303.
   PubMed Web of Science ®Google Scholar
• Han, C., Kasai, N., & Torimitsu, K. (2005). CA2: The most vulnerable sector to bicuculline exposure in rat hippocampal slice cultures. Neuroreport, 16(4), 333–336.
   PubMed Web of Science ®Google Scholar
• Heinemann, U., Buchheim, K., Gabriel, S., Kann, O., Kovács, R., & Schuchmann, S. (2002). Coupling of electrical and metabolic activity during epileptiform discharges. Epilepsia, 43(Suppl. 5), 168–173.
   PubMed Web of Science ®Google Scholar
• Heinemann, U., Lux, H. D., & Gutnick, M. J. (1977). Extracellular free calcium and potassium during paroxsmal activity in the cerebral cortex of the cat. Experimental Brain Research, 27(3–4), 237–243.
   PubMed Web of Science ®Google Scholar
• Ikegaya, Y. (1999). Abnormal targeting of developing hippocampal mossy fibers after epileptiform activities via L-type Ca2+ channel activation in vitro. Journal of Neuroscience, 19(2), 802–812.
   PubMed Web of Science ®Google Scholar
• Kovács, R., Gutierrez, R., Kivi, A., Schuchmann, S., Gabriel, S., & Heinemann, U. (1999). Acute cell damage after low Mg2+-induced epileptiform activity in organotypic hippocampal slice cultures. Neuroreport, 10(2), 207–213.
   PubMed Web of Science ®Google Scholar
• Kovács, R., Schuchmann, S., Gabriel, S., Kann, O., Kardos, J., & Heinemann, U. (2002). Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures. Journal of Neurophysiology, 88, 2909–2918.
   PubMed Web of Science ®Google Scholar
• Kovács, R., Szilagyi, N., Barabas, P., Heinemann, U., & Kardos, J. (2000). Low-[Mg2+]-induced Ca2+ fluctuations in organotypic hippocampal slice cultures. Neuroreport, 11(10), 2107–2111.
   PubMed Web of Science ®Google Scholar
• Muller, M., Gahwiler, B. H., Rietschin, L., & Thompson, S. M. (1993). Reversible loss of dendritic spines and altered excitability after chronic epilepsy in hippocampal slice cultures. Proceedings of the National Academy of Sciences of the United States of America, 90, 257–261.
   Google Scholar
• Olsen, R. W., Ban, M., & Miller, T. (1976). Studies on the neuropharmacological activity of bicuculline and related compounds. Brain Research, 102(2), 283–299.
   PubMed Web of Science ®Google Scholar
• Pitkanen, A., Schwartzkroin, P. A., & Moshé, S. L. (Eds.). (2005). Models of seizures and epilepsy. San Diego, CA: Academic.
   Google Scholar
• Pomper, J. K., Hoffmann, U., Kovács, R., Gabriel, S., & Heinemann, U. (2004). Hyperoxia is not an essential condition for status epilepticus induced cell death in organotypic hippocampal slice cultures. Epilepsy Research, 59(1), 61–65.
   PubMed Web of Science ®Google Scholar
• Poulsen, F. R., Jahnsen, H., Blaabjerg, M., & Zimmer, J. (2002). Pilocarpine-induced seizure-like activity with increased BNDF and neuropeptide Y expression in organotypic hippocampal slice cultures. Brain Research, 950(1), 103–118.
   PubMed Web of Science ®Google Scholar
• Stafstrom, C. E., Ockuly, J. C., Murphree, L., Valley, M. T., Roopra, A., & Sutula, T. P. (2009). Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models. Annals of Neurology, 65(4), 435–447.
   PubMed Web of Science ®Google Scholar
• Stoppini, L., Buchs, P. A., & Muller, D. (1991). A simple method for organotypic cultures of nervous tissue. Journal of Neuroscience Methods, 37(2), 173–182.
   PubMed Web of Science ®Google Scholar
• Walther, H., Lambert, J. D., Jones, R. S., Heinemann, U., & Hamon, B. (1986). Epileptiform activity in combined slices of the hippocampus, subiculum and entorhinal cortex during perfusion with low magnesium medium. Neuroscience Letters, 69(2), 156–161.
   PubMed Web of Science ®Google Scholar
• Zhang, J. W., Deb, S., & Gottschall, P. E. (1998). Regional and differential expression of gelatinases in rat brain after systemic kainic acid or bicuculline administration. European Journal of Neuroscience, 10(11), 3358–3368.
   PubMed Web of Science ®Google Scholar