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Research Article

Effects of Glial Cell Line-Derived Neurotrophic Factor Intrathecal Injection on Spinal Dorsal Horn Glial Fibrillary Acidic Protein Expression in a Rat Model of Neuropathic Pain

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Pages 388-394 | Received 20 Jul 2011, Published online: 20 Apr 2012

REFERENCES

  • Ramer MS, Priestley JV, McMahon SB. Functional regeneration of sensory axons into the adult spinal cord. Nature. 2000;403:312–6.
  • Boucher TJ, Okuse K, Bennett DL, Munson JB, Wood JN, McMahon SB. Potent analgesic effects of GDNF in neuropathic pain states. Science. 2000;290:124–7.
  • Sakai A, Asada M, Seno N, Suzuki H. Involvement of neural cell adhesion molecule signaling in glial cell line-derived neurotrophic factor-induced analgesia in a rat model of neuropathic pain. Pain. 2008;137:378–88.
  • Pezet S, Krzyzanowska A, Wong LF, Grist J, Mazarakis ND, Georqievska B, McMahon SB. Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF. Mol Ther. 2006;13(6):1101–9.
  • Ricart K, Pearson RJ, Viera L, Cassina P, Kamaid A, Carroll SL, Estévez AG. Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis. J Neurochem. 2006;97:222–33.
  • Watanabe M. Glial processes are glued to synapses via Ca2+-permeable glutamate receptors. Trends Neurosci. 2002;25: 5–6.
  • DeLeo JA, Tanga FY, Tawfik VL. Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist. 2004;10:40–52.
  • Ying B, Lu N, Zhang YQ, Zhao ZQ. Involvement of spinal glia in tetanically sciatic stimulation-induced bilateral mechanical allodynia in rats. Biochem Biophys Res Commun. 2006;340:1264–72.
  • Wieseler-Frank J, Maier SF, Wathins LR. Glia activation and pathological pain. Neurochem Int. 2004;45:389–95.
  • Fang M, Wang Y, He QH, Sun YX, Deng LB, Wang XM, Han JS. Glial cell line-derived neurotrophic factor contributes to delayed inflammatory hyperalgesia in adjuvant rat pain model. Neuroscience. 2003;117(3):503–12.
  • Ren K, Dubner R. Interactions between the immune and nervous systems in pain. Nat Med. 2010;16:1267–76.
  • Guo JR, Jia DL, Jin BW, Lian JF, Yuan XH, Shen HC. Inhibitory effect of glial cell line-derived neurotrophic factors via subarachnoid space administration on glial fibrillary acidic protein expression in the spinal dorsal horn of rats with spinal nerve ligation. Chin J Pharmacol Toxicol. 2011;25: 235–9.
  • Zhuang ZY, Gerner P, Woof CJ, Ji RR. ERK is sequentially activated in neurons, microglia, and ast rocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain. 2005;114:149–59.
  • Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends Neurosci. 2001;24:450–5.
  • Kim SH, Chung JM. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain. 1992;50:355–63.
  • Storkson R, Kjorstvik A, Tjolsen A, Hole K. Lumbar catheterization of the spinal subarachnoid space in the rat. J Neurosci Methods. 1996;65:167–72.
  • Sweitzer SM, Colburn RW, Rutkowski M, Deleo JA. Acute peripheral inflammation induces moderate glial activation and spinal IL-1 β expression that correlates with pain behavior in the rat. Brain Res. 1999;829:209–21.
  • Hashizume H, DeLeo JA, Colburn RW, Weistein JN. Spinal glial activation and cytokine expression after lumbar root injury in the rat. Spine. 2000;25:1206–17.
  • Sweitzer SM, Schubert P, DeLeo JA. Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain. J Pharmacol Exp Ther. 2001;297:1210–7.
  • Wieseler FJ, Maier SF, Watkins LR. Glial activation and pathological pain. Neurochem Int. 2004;45:389–95.
  • Takeda K, Sawamura S, Tamai H, Sekiyama H, Hanaoka K. Role for cyclooxygenase in the development and maintenance of neuropathic pain and spinal glial activation. Anesthesiology. 2005;103:837–44.
  • Zhang Q, Haydon PG. Roles for gliotransmission in the nervous system. J Neural Transm. 2005;112:121–5.
  • Moalem G, Tracey DJ. Immune and inflammatory mechanisms in neuropathic pain. Brain Res Rev. 2006;51:240–64.
  • Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends Neurosci. 2001;24:450–5.
  • Woolf CJ, Shortland P, Coggeshall RE. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature. 1992;355:75–8.
  • Zwick M, Davis BM, Woodbury CJ, Burkett JN, Koerber HR, Simpson JF, Alberts KM. Glial cell line-derived neurotrophic factor is a survival factor for isolectin B4-positive, but not vanilloid receptor 1-positive, neurons in the mouse. J Neurosci. 2002;22:4057–65.
  • Ogun-Muyiwa P, Helliwell R, McIntyre P, Winter J. Glial cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons. Neuroreport. 1999;10:2107–11.
  • Malcangio M. GDNF and somatostatin in sensory neurons. Curr Opin Pharmacol. 2003;3:41–5.
  • Wang R, Guo W, Ossipov MH, Vanderah TW, Porreca F, Lai J. Glial cell line derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain. Neuroscience. 2003;121:815–24.

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