Protective effects of recombinant human bone morphogenetic protein-7 on focal cerebral ischemia–reperfusion injury

References

• Berti R, Williams AJ, Moffett JR, Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury. J Cereb Blood Flow Metab 2002;22:1068–79.
   PubMed Web of Science ®Google Scholar
• Huang Q, Tatro JB. Alpha-melanocyte stimulating hormone suppresses intracerebral tumor necrosis factor-alpha and interleukin-1beta gene expression following transient cerebral ischemia in mice. Neurosci Lett 2002;334:186–90.
   PubMed Web of Science ®Google Scholar
• Clemens JA, Stephenson DT, Yin T, Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-kappa B in rats. Stroke 1998;29:677–82.
   PubMed Web of Science ®Google Scholar
• Urist MR, Mikulski A, Conteas CN. Reversible extinction of the morphogen in bone matrix by reduction and oxidation of disulfide bonds. Calcif Tissue Res 1975;19:73–83.
   PubMedGoogle Scholar
• Chen D, Zhao M, Mundy GR. Bone morphogenetic proteins. Growth Factors 2004;22:233–41.
   PubMed Web of Science ®Google Scholar
• Ducy P, Karsenty G. The family of bone morphogenetic proteins. Kidney Int 2000;57:2207–14.
   PubMed Web of Science ®Google Scholar
• Wozney JM. Overview of bone morphogenetic proteins. Spine (Phila Pa 1976) 2002;27:S2–8.
   PubMed Web of Science ®Google Scholar
• Harvey BK, Hoffer BJ, Wang Y. Stroke and TGF-beta proteins: glial cell line-derived neurotrophic factor and bone morphogenetic protein. Pharmacol Ther 2005;105:113–25
   PubMed Web of Science ®Google Scholar
• Chang CF, Morales M, Chou J, Bone morphogenetic proteins are involved in fetal kidney tissue transplantation-induced neuroprotection in stroke rats. Neuropharmacol 2002;43:418–26.
   Google Scholar
• Charytoniuk DA, Traiffort E, Pinard E, Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia. Neuroscience 2000;100:33–43.
   PubMedGoogle Scholar
• Chang CF, Lin SZ, Chiang YH, Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke 2003;34:558–64.
   PubMedGoogle Scholar
• Chou J, Harvey BK, Chang CF, Neuroregenerative effects of BMP7 after stroke in rats. J Neurol Sci 2006;240:21–9.
   PubMed Web of Science ®Google Scholar
• Simon M, Maresh JG, Harris SE, Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney. Am J Physiol 1999;276:F382–9.
   PubMed Web of Science ®Google Scholar
• Lin SZ, Hoffer BJ, Kaplan P, Wang Y. Osteogenic protein-1 protects against cerebral infarction induced by MCA ligation in adult rats. Stroke 1999;30:126–33.
   Google Scholar
• Xu JH, Zhao YY, Wang JK, Effects of mouse recombinant bone morphogenetic protein-7 transfection on cell apoptosis, NF-kappa B, and downstream genes in cultured primary cardiomyocytes after simulated ischemia and reperfusion injury. J Cardiovasc Pharmacol 2010;56:69–77.
   Google Scholar
• Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989;20:84–91.
   PubMed Web of Science ®Google Scholar
• Almanzar MM, Frazier KS, Dube PH, Osteogenic protein-1 mRNA expression is selectively modulated after acute ischemic renal injury. J Am Soc Nephrol 1998;9:1456–63.
   PubMed Web of Science ®Google Scholar
• Zhen-Qiang F, Bing-Wei Y, Yong-Liang L, Localized expression of human BMP-7 by BM-MSCs enhances renal repair in an in vivo model of ischemia-reperfusion injury. Genes Cells 2012;17:53–64.
   PubMed Web of Science ®Google Scholar
• Nakazawa J, Isshiki K, Sugimoto T, Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia-reperfusion-induced acute kidney injury. Nephrology (Carlton) 2010;15:93–101.
   Google Scholar
• Shen H, Luo Y, Kuo CC, Wang Y. BMP7 reduces synergistic injury induced by methamphetamine and ischemia in mouse brain. Neurosci Lett 2008;442:15–8.
   Google Scholar
• Radhakrishnan RS, Radhakrishnan GL, Radhakrishnan HR, Pretreatment with bone morphogenetic protein-7 (BMP-7) mimics ischemia preconditioning following intestinal ischemia/reperfusion injury in the intestine and liver. Shock 2008;30:532–6.
   Google Scholar
• Lefer AM, Tsao PS, Ma XL, Sampath TK. Anti-ischaemic and endothelial protective actions of recombinant human osteogenic protein (hOP-1). J Mol Cell Cardiol 1992;24:585–93.
   Google Scholar
• Vukicevic S, Basic V, Rogic D, Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat. J Clin Invest 1998;102:202–14.
   PubMed Web of Science ®Google Scholar
• Jordan J, Bottner M, Schluesener HJ, Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. Eur J Neurosci 1997;9:1699–709.
   PubMed Web of Science ®Google Scholar
• Mehler MF, Mabie PC, Zhang D, Kessler JA. Bone morphogenetic proteins in the nervous system. Trends Neurosci 1997;20:309–17.
   PubMedGoogle Scholar
• Marumo T, Hishikawa K, Yoshikawa M, Fujita T. Epigenetic regulation of BMP7 in the regenerative response to ischemia. J Am Soc Nephrol 2008 Jul;19(7):1311–20.
   Google Scholar
• Liu Y, Belayev L, Zhao W, The effect of bone morphogenetic protein-7 (BMP-7) on functional recovery, local cerebral glucose utilization and blood flow after transient focal cerebral ischemia in rats. Brain Res 2001;905:81–90.
   PubMedGoogle Scholar
• Esquenazi S, Monnerie H, Kaplan P, BMP-7 and excess glutamate: opposing effects on dendrite growth from cerebral cortical neurons in vitro. Exp Neurol. 2002;176(1): 41–54.
   Google Scholar
• Lee MJ, Yang CW, Jin DC, Bone morphogenetic protein-7 inhibits constitutive and interleukin-1 beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells: role for JNK/AP-1 pathway. J Immunol 2003;170:2557–63.
   Google Scholar
• Gould SE, Day M, Jones SS, Dorai H. BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells. Kidney Int 2002;61:51–60.
   PubMed Web of Science ®Google Scholar
• Shen H, Luo Y, Kuo CC, Wang Y. BMP7 reduces synergistic injury induced by methamphetamine and ischemia in mouse brain. Neurosci Lett 2008;442:15–8.
   Google Scholar
• Cox S, Harvey BK, Sanchez JF, Mediation of BMP7 neuroprotection by MAPK and PKC IN rat primary cortical cultures. Brain Res 2004;1010:55–61.
   Google Scholar
• Schneider A, Martin-Villalba A, Weih F, NF-kappa B is activated and promotes cell death in focal cerebral ischemia. Nat Med. 1999;5:554–9.
   PubMed Web of Science ®Google Scholar
• Clemens JA, Stephenson DT, Dixon EP, Global cerebral ischemia activates nuclear factor-kappa B prior to evidence of DNA fragmentation. Brain Res Mol Brain Res 1997;48: 187–96.
   PubMedGoogle Scholar
• Carroll JE, Howard EF, Hess DC, Nuclear factor-kappa B activation during cerebral reperfusion: effect of attenuation with N-acetylcysteine treatment. Brain Res Mol Brain Res 1998;56:186–91.
   PubMedGoogle Scholar
• Botchkina GI, Geimonen E, Bilof ML, Loss of NF-kappa B activity during cerebral ischemia and TNF cytotoxicity. Mol Med 1999;5:372–81.
   PubMed Web of Science ®Google Scholar