106
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Cerebrospinal fluid nitric oxide metabolite levels as a biomarker in severe traumatic brain injury

, , &
Pages 385-391 | Received 16 Apr 2012, Accepted 20 Dec 2012, Published online: 06 Feb 2013

References

  • Bullock R, Chesnut R, Clifton G, Guidelines for the management of severe head injury. Brain Trauma Foundation. Eur J Emerg Med (official journal of the European Society for Emergency Medicine) 1996;3:109–127.
  • Kövesdi E, Lückl J, Bukovics P, Update on protein biomarkers in traumatic brain injury with emphasis on clinical use in adults and pediatrics. Acta Neurochirurgica 2010;152:1–17.
  • Rangel-Castilla L, Robertson CS. Nitric oxide metabolism after traumatic brain injury. Intensive Care Med Ann Update 2007:739–47.
  • Faraci FM, Brian J. Nitric oxide and the cerebral circulation. Stroke 1994;25:692–703.
  • Chao C, Hu S, Molitor T, Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J Immunol 1992;149:2736–41.
  • Merrill J, Ignarro L, Sherman M, Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol 1993;151:2132–41.
  • Bratasz A, Kuter I, Konior R, Nitric oxide as a prognostic marker for neurological diseases. Antioxid Redox Signal 2004;6:613–7.
  • Heneka MT, Löschmann PA, Gleichmann M, Induction of nitric oxide synthase and nitric oxide mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor/lipopolysaccharide. J Neurochem 1998;71:88–94.
  • Holmin S, Söderlund J, Biberfeld P, Mathiesen T. Intracerebral inflammation after human brain contusion. Neurosurgery 1998;42:291–9.
  • Lu YC, Liu S, Gong QZ, Inhibition of nitric oxide synthase potentiates hypertension and increases mortality in traumatically brain-injured rats. Mol Chem Neuropathol 1997;30:125–37.
  • Mesenge C, Verrecchia C, Allix M, Reduction of the neurological deficit in mice with traumatic brain injury by nitric oxide synthase inhibitors. J Neurotrauma 1996;13:11–6.
  • Shohami E, Kohen R. The role of reactive oxygen species in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology. Springer, New York: Humana Press; 2011:99–118.
  • Gahm C, Holmin S, Mathiesen T. Nitric oxide synthase expression after human brain contusion. Neurosurgery 2002;50:1319–26.
  • Dong Z, Mingde Q, Yujuan G, Ling L. Changes of nitric oxide and its relationship with clinical features, intracranial pressure and outcome in acute head injury. Journal of Tongji Medical University 2000;20:148–50.
  • Clark RSB, Kochanek PM, Obrist WD, Cerebrospinal fluid and plasma nitrite and nitrate concentrations after head injury in humans. Crit Care Med 1996;24:1243–51.
  • Uzan M, Tanriover N, Bozkus H, Nitric oxide (NO) metabolism in the cerebrospinal fluid of patients with severe head injury: inflammation as a possible cause of elevated no metabolites. Surg Neurol 2001;56:350–6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.