References
- Lin LF, Doherty DH, Lile JD, GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993;260:1130–2.
- Kobayashi H, Fukuhara K, Tada-Oikawa S, The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease. J Neurochem 2009;108(2):397–407.
- Chipuk JE, Fisher JC, Dillon CP, Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins. PNAS 2008;105:20327–32.
- Paradis E, Douillard HE, Koutroumanis M, Amyloid β peptide of Alzheimer's disease downregulates Bcl-2 and upregulates Bax expression in human neurons. J Neurosci 1996;16:7533–9.
- Cheng B, Yang X, Hou Z, D-beta-hydroxybutyrate inhibits the apoptosis of PC12 cells induced by 6-OHDA in relation to up-regulating the ratio of Bcl-2/Bax mRNA. Auton Neurosci 2007;134(1–2):38–44.
- Kramer BC, Mytilineou C. Alterations in the cellular distribution of bcl-2, bcl-x and bax in the adult rat substantia nigra following striatal 6-hydroxydopamine lesions. J Neurocytol 2004;33(2):213–23.
- Karin M, Yamamoto Y, Wang QM. The IKK NF-kappa B system: a treasure trove for drug development. Nat Rev Drug Discov 2004;3:17–26.
- Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998;16:225–60.
- Lich JD, Williams KL, Moore CB, Cutting edge: monarch-1 suppresses non-canonical NF-κB activation and p52-dependent chemokine expression in monocytes. J Immunol 2007;178:1256-60.
- Cao JP, Wang HJ, Yu JK, The involvement of NF-kappaB p65/p52 in the effects of GDNF on DA neurons in early PD rats. Brain Res Bull 2008;76(5):505–11.
- Sun Y, Huang XG, Liu MY, A new alternative NF-κB Pathway mediated the neuroprotection of GDNF on 6-OHDA-induced DA neurons neurotoxicity. Brain Res 2012;1437:38–49.
- Choi HK, Won LA, Kontur PJ, Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion. Brain Res 1991;552(1):67–76.
- Choi HK, Won LA, Roback JD, Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions. PNAS 1992;89: 8943–7.
- Rolland AS, Herrero MT, Virginia GM, Metabolic activity of cerebellar and basal ganglia-thalamic neurons is reduced in parkinsonism. Brain 2007;130:265–75.
- Gorman AM, Szegezdi E, Quigney DJ, Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells. Biochem Biophys Res Commun 2005;327(3):801–10.
- Hu XM, Weng ZF, Chu CT, Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade. J Neurosci 2011;31:247–61.
- Ugarte SD, Lin E, Klann E, Effects of GDNF on 6-OHDA-induced death in a dopaminergic cell line: modulation by inhibitors of PI3 kinase and MEK. J Neurosci Res 2003;73(1):105–12.
- Holmgreen SP, Huang DC, Adams JM, Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members. Cell Death Differ 1999;6(6):525–32.
- Lang-Rollin I, Maniati M, Jabado O, Apoptosis and the conformational change of Bax induced by proteasomal inhibition of PC12 cells are inhibited by bcl-xL and bcl-2. Apoptosis 2005;10(4):809–20.
- Manakova S, Puttonen KA, Raasmaja A, The roles of dopamine transporter and Bcl-2 protein in the protection of CV1-P cells from 6-OHDA-induced toxicity. Toxicol Lett 2004;154:117–23.
- Natsume A, Mata M, Goss J, Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration. Exp Neurol 2001;169(2):231–8.
- Ebadi M, Sharma SK, Wanpen S, Coenzyme Q10 inhibits mitochondrial complex-1 down-regulation and nuclear factor-kappa B activation. J Cell Mol Med 2004;8:213–22.
- Ghosh A, Roy A, Liu XJ, Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. PNAS 2007;104:18754–9.
- Saldana M, Bonastre M, Aguilar E, Role of nigral NFkappaB p50 and p65 subunit expression in haloperidol-induced neurotoxicity and stereotyped behavior in rats. Eur Neuropsychopharmacol 2006;16(7):491–497.
- Lee HH, Dadgostar H, Cheng QW, NF-κB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. PNAS 1996; 96:9136–41.
- Liu S, Shen H, Xu M, FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-κB-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model. Am J Physiol Endocrinol Metab 2010;299:E351–63.
- Matsushita H, Morishita R, Nata T, Hypoxia-induced endothelial apoptosis through nuclear factor-κB (NF-κB)–mediated bcl-2 suppression in vivo evidence of the importance of NF-κB in endothelial cell regulation. Circ Res 2000;86:974–81.
- Zong WX, Edelstein LC, Chen C, The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis. Genes & Dev 1999;13:382–7.
- Senftleben U, Cao YX, Xiao GT, Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway, Science 2001;293:1495–9.
- Xiao GT, Fong A, Sun SC. Induction of p100 processing by NF-κB-inducing kinase involves docking IκB kinaseα (IKKα) to p100 and IKKα-mediated phosphorylation. J Biol Chem 2004;279:30099-105.