References
- Warner TT, Schapira AH. Genetic and environmental factors in the cause of Parkinson's disease. Ann Neurol 2003;53(Suppl 3): S16–23; discussion S23–15.
- Reichardt LF. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 2006;361: 1545–64.
- Hyman C, Hofer M, Barde YA, BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 1991;350:230–2.
- Mogi M, Togari A, Kondo T, Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci Lett 1999;270:45–8.
- Fumagalli F, Racagni G, Riva MA. Shedding light into the role of BDNF in the pharmacotherapy of Parkinson's disease. Pharmacogenomics J 2006;6:95–104.
- Kishikawa S, Li JL, Gillis T, Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington's disease. Neurobiol Dis 2006;24:280–5.
- Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959;22:719–48.
- DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177–88.
- Xiromerisiou G, Hadjigeorgiou GM, Eerola J, BDNF tagging polymorphisms and haplotype analysis in sporadic Parkinson's disease in diverse ethnic groups. Neurosci Lett 2007;415:59–63.
- Liu QR, Walther D, Drgon T, Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. Am J Med Genet B Neuropsychiatr Genet 2005;134B:93–103.
- Karamohamed S, Latourelle JC, Racette BA, BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study. Neurology 2005;65:1823–5.
- Parsian A, Sinha R, Racette B, Association of a variation in the promoter region of the brain-derived neurotrophic factor gene with familial Parkinson's disease. Parkinsonism Relat Disord 2004;10:213–9.
- Toda T, Momose Y, Murata M, Toward identification of susceptibility genes for sporadic Parkinson's disease. J Neurol 2003;250(Suppl 3):III40–3.
- Momose Y, Murata M, Kobayashi K, Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms. Ann Neurol 2002;51:133–6.
- Zintzaras E, Hadjigeorgiou GM. The role of G196A polymorphism in the brain-derived neurotrophic factor gene in the cause of Parkinson's disease: a meta-analysis. J Hum Genet 2005;50:560–6.
- Liu J, Zhou Y, Wang C, Brain-derived neurotrophic factor (BDNF) genetic polymorphism greatly increases risk of leucine-rich repeat kinase 2 (LRRK2) for Parkinson's disease. Parkinsonism Relat Disord 2012;18:140–3.
- Lin CH, Wu RM, Tai CH, Lrrk2 S1647T and BDNF V66M interact with environmental factors to increase risk of Parkinson's disease. Parkinsonism Relat Disord 2011;17:84–8.
- Karakasis C, Kalinderi K, Katsarou Z, Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with Parkinson's disease in a Greek population. J Clin Neurosci 2011;18:1744–5.
- Chen L, Wang Y, Xiao H, The 712A/G polymorphism of Brain-derived neurotrophic factor is associated with Parkinson's disease but not Major Depressive Disorder in a Chinese Han population. Biochem Biophys Res Commun 2011;408:318–21.
- Gao L, Diaz-Corrales FJ, Carrillo F, Brain-derived neurotrophic factor G196A polymorphism and clinical features in Parkinson's disease. Acta Neurol Scand 2010;122:41–5.
- Benitez BA, Forero DA, Arboleda GH, Exploration of genetic susceptibility factors for Parkinson's disease in a South American sample. J Genet 2010;89:229–32.
- Guerini FR, Beghi E, Riboldazzi G, BDNF Val66Met polymorphism is associated with cognitive impairment in Italian patients with Parkinson's disease. Eur J Neurol 2009;16:1240–5.
- Chen CM, Chen IC, Chang KH, Nuclear receptor NR4A2 IVS6 +18insG and brain derived neurotrophic factor (BDNF) V66M polymorphisms and risk of Taiwanese Parkinson's disease. Am J Med Genet B Neuropsychiatr Genet 2007;144B:458–62.
- Saarela MS, Lehtimaki T, Rinne JO, No association between the brain-derived neurotrophic factor 196 G>A or 270 C>T polymorphisms and Alzheimer's or Parkinson's disease. Folia Neuropathol 2006;44:12–6.
- Nishimura M, Kuno S, Kaji R, Kawakami H. Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy. Mov Disord 2005;20:1031–3.
- Masaki T, Matsushita S, Arai H, Association between a polymorphism of brain-derived neurotrophic factor gene and sporadic Parkinson's disease. Ann Neurol 2003;54: 276–7.
- Hong CJ, Liu HC, Liu TY, Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset. Neurosci Lett 2003;353:75–7.
- Hakansson A, Melke J, Westberg L, Lack of association between the BDNF Val66Met polymorphism and Parkinson's disease in a Swedish population. Ann Neurol 2003;53: 823.
- Samii A, Nutt JG, Ransom BR. Parkinson's disease. Lancet 2004;363:1783–93.
- Driver JA, Logroscino G, Gaziano JM, Kurth T. Incidence and remaining lifetime risk of Parkinson disease in advanced age. Neurology 2009;72:432–8.
- Ghione I, Di Fonzo A, Saladino F, Parkin polymorphisms and environmental exposure: decrease in age at onset of Parkinson's disease. Neurotoxicology 2007;28:698–701.