172
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Different effects of etomidate and propofol on memory in immature rats

, , , , , & show all
Pages 66-69 | Received 06 Feb 2014, Accepted 04 Mar 2014, Published online: 08 Apr 2014

References

  • Wang C, Slikker W, Jr. Strategies and experimental models for evaluating anesthetics: effects on the developing nervous system. Anesth Analg 2008;106(6):1643–58.
  • Rasmussen LS. Postoperative cognitive dysfunction: incidence and prevention. Best practiceBest Pract Res Clin Anaesthesiol 2006;20(2):315–30.
  • Crosby G, Culley DJ. Surgery and anesthesia: healing the body but harming the brain? Anesth Analg 2011;112(5):999–1001.
  • Sun L. Early childhood general anaesthesia exposure and neurocognitive development. Br J Anaesth 2010;105(Suppl 1):i61–8.
  • DiMaggio C, Sun LS, Li G. Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a sibling birth cohort. Anesth Analg 2011;113(5):1143–51.
  • Li GD, Chiara DC, Sawyer GW, Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog. J Neurosci: the official journal of the Society for Neuroscience 2006;26(45):11599–605.
  • Bali M, Akabas MH. Defining the propofol binding site location on the GABAA receptor. Mol Pharmacol 2004;65(1):68–76.
  • Yip GM, Chen ZW, Edge CJ, A propofol binding site on mammalian GABA receptors identified by photolabeling. Nature Chem Biol 2013;9:714–20.
  • Mellon RD, Simone AF, Rappaport BA. Use of anesthetic agents in neonates and young children. Anesth Analg 2007;104(3):509–20.
  • Bercker S, Bert B, Bittigau P, Neurodegeneration in newborn rats following propofol and sevoflurane anesthesia. Neurotox Res 2009;16(2):140–7.
  • Karen T, Schlager GW, Bendix I, Effect of propofol in the immature rat brain on short- and long-term neurodevelopmental outcome. PloS One 2013;8(5):e64480.
  • Wagner RL, White PF, Kan PB, Inhibition of adrenal steroidogenesis by the anesthetic etomidate. N Engl J Med 1984;310(22):1415–21.
  • Martin LJ, Oh GH, Orser BA. Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade. Anesthesiology 2009;111(5):1025–35.
  • Rice D, Barone S, Jr. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 2000;108(Suppl 3): 511–33.
  • Forman SA. Clinical and molecular pharmacology of etomidate. Anesthesiology 2011;114(3):695–707.
  • Jonsson Fagerlund M, Sjodin J, Krupp J, Dabrowski MA. Reduced effect of propofol at human {alpha}1{beta}2(N289M) {gamma}2 and {alpha}2{beta}3(N290M){gamma}2 mutant GABA(A) receptors. Br J Anaesth 2010;104(4): 472–81.
  • Cheng VY, Martin LJ, Elliott EM, Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate. J Neurosci: the official journal of the Society for Neuroscience 2006;26(14): 3713–20.
  • Collinson N, Kuenzi FM, Jarolimek W, Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor. J Neurosci : the official journal of the Society for Neuroscience 2002;22(13):5572–80.
  • Mohler H. Role of GABAA receptors in cognition. Biochem Soc Trans 2009;37(Pt 6):1328–33.
  • Murugaiah KD, Hemmings HC, Jr. Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes. Anesthesiology 1998;89(4):919–28.
  • Yoon JH, Maddock RJ, Rokem A, GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression. J Neurosci : the official journal of the Society for Neuroscience 2010;30(10):3777–81.
  • Kegeles LS, Mao X, Stanford AD, Elevated prefrontal cortex gamma-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. Arch Gen Psychiatry 2012;69(5): 449–59.
  • Tayoshi S, Nakataki M, Sumitani S, GABA concentration in schizophrenia patients and the effects of antipsychotic medication: a proton magnetic resonance spectroscopy study. Schizophr Res 2010;117(1):83–91.
  • Zhang SS, Zhu TJ, Zhang DS, Chen XY. [Effects of cerebral GABA level on learning and memory]. Zhongguo Yao Li Xue Bao. 1989;10(1):10–2.
  • Nabeshima T, Noda Y, Kameyama T. GABAergic modulation of memory with regard to passive avoidance and conditioned suppression task in mice. Psychopharmacology 1988;94(1):69–73.
  • Patel S, Wohlfeil ER, Rademacher DJ, The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. Br J Pharmacol 2003;139(5):1005–13.
  • Pearn ML, Hu Y, Niesman IR, Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation. Anesthesiology 2012;116(2):352–61.
  • Spahr-Schopfer I, Vutskits L, Toni N, Differential neurotoxic effects of propofol on dissociated cortical cells and organotypic hippocampal cultures. Anesthesiology 2000;92(5):1408–17.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.