Association study of CREB1 polymorphisms and suicidality in MDD: results from a European multicenter study on treatment resistant depression

References

• Wittchen HU, Pittrow D. Prevalence, recognition and management of depression in primary care in Germany: the Depression 2000 study. Hum Psychopharmacol 2002;17(Suppl 1):S1–11.
   PubMed Web of Science ®Google Scholar
• Geddes JR, Freemantle N, Mason J, et al. SSRIs versus other antidepressants for depressive disorder. Cochrane Database Syst Rev 2000(2):CD001851.
   Google Scholar
• Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry 2006 Nov;163(11):1905–17.
   PubMed Web of Science ®Google Scholar
• Papakostas GI, Petersen T, Pava J, et al. Hopelessness and suicidal ideation in outpatients with treatment-resistant depression: prevalence and impact on treatment outcome. J Nerv Ment Dis 2003 Jul;191(7):444–9.
   PubMed Web of Science ®Google Scholar
• Souery D, Oswald P, Massat I, et al. Clinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study. J Clin Psychiatry 2007 Jul;68(7):1062–70.
   PubMed Web of Science ®Google Scholar
• Pless IB. Keys to success: WHO's world report on violence and health, Montreal declaration, motor vehicle injuries. Inj Prev: journal of the International Society for Child and Adolescent Injury Prevention. 2002 Sep;8(3):173–4.
   Google Scholar
• Mann JJ. A current perspective of suicide and attempted suicide. Ann Intern Med 2002;136(4):302–11.
   PubMed Web of Science ®Google Scholar
• Brent DA, Mann JJ. Family genetic studies, suicide, and suicidal behavior. Am J Med Genet Part C, Semin Med Genet 2005;133C(1):13–24.
   PubMed Web of Science ®Google Scholar
• Fu Q, Heath AC, Bucholz KK, et al. A twin study of genetic and environmental influences on suicidality in men. Psychol Med 2002;32(1):11–24.
   PubMed Web of Science ®Google Scholar
• Glowinski AL, Bucholz KK, Nelson EC, et al. Suicide attempts in an adolescent female twin sample. J Am Acad Child Adolesc Psychiatry 2001;40(11):1300–7.
   PubMed Web of Science ®Google Scholar
• Statham DJ, Heath AC, Madden PA, et al. Suicidal behaviour: an epidemiological and genetic study. Psychol Med 1998;28(4):839–55.
   PubMed Web of Science ®Google Scholar
• Schosser A, Butler AW, Ising M, et al. Genomewide association scan of suicidal thoughts and behaviour in major depression. PloS One 2011;6(7):e20690.
   PubMed Web of Science ®Google Scholar
• Duman RS, Malberg J, Thome J. Neural plasticity to stress and antidepressant treatment. Biol Psychiatry 1999;46(9):1181–91.
   PubMed Web of Science ®Google Scholar
• Chen B, Dowlatshahi D, MacQueen GM, et al. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 2001;50(4):260–5.
   PubMed Web of Science ®Google Scholar
• Manji HK, Drevets WC, Charney DS. The cellular neurobiology of depression. Nat Med 2001;7(5):541–7.
   PubMed Web of Science ®Google Scholar
• Neves-Pereira M, Mundo E, Muglia P, et al. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet 2002;71(3):651–5.
   PubMed Web of Science ®Google Scholar
• Sklar P, Gabriel SB, McInnis MG, et al. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol Psychiatry 2002;7(6):579–93.
   PubMed Web of Science ®Google Scholar
• Egan MF, Kojima M, Callicott JH, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112(2):257–69.
   PubMed Web of Science ®Google Scholar
• Blendy JA. The role of CREB in depression and antidepressant treatment. Biol Psychiatry 2006;59(12):1144–50.
   PubMed Web of Science ®Google Scholar
• Ren X, Dwivedi Y, Mondal AC, Pandey GN. Cyclic-AMP response element binding protein (CREB) in the neutrophils of depressed patients. Psychiatry Res 2011;185(1–2):108–12.
   PubMed Web of Science ®Google Scholar
• Tardito D, Perez J, Tiraboschi E, et al. Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview. Pharmacol Rev 2006;58(1):115–34.
   PubMed Web of Science ®Google Scholar
• Dowlatshahi D, MacQueen GM, Wang JF, et al. G Protein-coupled cyclic AMP signaling in postmortem brain of subjects with mood disorders: effects of diagnosis, suicide, and treatment at the time of death. J Neurochem 1999;73(3):1121–6.
   PubMed Web of Science ®Google Scholar
• Dwivedi Y, Rao JS, Rizavi HS, et al. Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003;60(3):273–82.
   PubMed Web of Science ®Google Scholar
• Young LT, Bezchlibnyk YB, Chen B, et al. Amygdala cyclic adenosine monophosphate response element binding protein phosphorylation in patients with mood disorders: effects of diagnosis, suicide, and drug treatment. Biol Psychiatry 2004;55(6):570–7.
   PubMed Web of Science ®Google Scholar
• Perlis RH, Beasley CM, Jr., Wines JD, Jr., et al. Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes. Psychother Psychosom 2007;76(1):40–6.
   PubMed Web of Science ®Google Scholar
• Perlis RH, Purcell S, Fava M, et al. Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Arch Gen Psychiatry 2007;64(6):689–97.
   PubMed Web of Science ®Google Scholar
• Hettema JM, An SS, van den Oord EJ, et al. Association study of CREB1 with Major Depressive Disorder and related phenotypes. Am J Med Genet Part B, Neuropsychiatric Genet: the official publication of the International Society of Psychiatric Genetics. 2009;150B(8):1128–32.
   PubMed Web of Science ®Google Scholar
• Serretti A, Chiesa A, Calati R, et al. A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression. J Affect Disord 2011;128(1–2):56–63.
   PubMed Web of Science ®Google Scholar
• Schosser A, Serretti A, Souery D, et al. European Group for the Study of Resistant Depression (GSRD)–where have we gone so far: review of clinical and genetic findings. Eur Neuropsychopharmacol the Journal of the European College of Neuropsychopharmacology. 2012;22(7):453–68.
   Google Scholar
• Schosser A, Calati R, Serretti A, et al. The impact of COMT gene polymorphisms on suicidality in treatment resistant major depressive disorder—a European multicenter study. Eur Neuropsychopharmacol: the Journal of the European College of Neuropsychopharmacology. 2012;22(4):259–66.
   Google Scholar
• Sheehan DV, Lecrubier Y, Sheehan KH, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998;59(Suppl 20):22–33;quiz 4–57.
   PubMed Web of Science ®Google Scholar
• Hamilton M. A rating scale for depression. J Neurol, Neurosurg Psychiatry 1960;23:56–62.
   PubMed Web of Science ®Google Scholar
• Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 2003;25(2):115–21.
   PubMed Web of Science ®Google Scholar
• Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21(2):263–5.
   PubMed Web of Science ®Google Scholar
• Benjamini Y, Drai D, Elmer G, et al. Controlling the false discovery rate in behavior genetics research. Behav Brain Res 2001;125(1–2):279–84.
   PubMed Web of Science ®Google Scholar
• Dupont WD, Plummer WD, Jr. Power and sample size calculations. A review and computer program. Control Clin Trials 1990 Apr;11(2):116–28.
   PubMedGoogle Scholar
• Laje G, Perlis RH, Rush AJ, McMahon FJ. Pharmacogenetics studies in STAR*D: strengths, limitations, and results. Psychiatric Serv 2009;60(11):1446–57.
   PubMed Web of Science ®Google Scholar
• Uher R, Perroud N. Probing the genome to understand suicide. Am J Psychiatry 2010;167(12):1425–7.
   PubMed Web of Science ®Google Scholar
• Imaki J, Yoshida K, Yamashita K. A developmental study of cyclic AMP-response element binding protein (CREB) by in situ hybridization histochemistry and immunocytochemistry in the rat neocortex. Brain Res 1994;651(1–2):269–74.
   PubMed Web of Science ®Google Scholar
• Dwivedi Y, Rizavi HS, Conley RR, et al. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003;60(8):804–15.
   PubMed Web of Science ®Google Scholar
• Nibuya M, Nestler EJ, Duman RS. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci: the Official journal of the Society for Neuroscience. 1996;16(7):2365–72.
   PubMed Web of Science ®Google Scholar
• Koch JM, Kell S, Hinze-Selch D, Aldenhoff JB. Changes in CREB-phosphorylation during recovery from major depression. J Psychiatric Res 2002;36(6):369–75.
   PubMed Web of Science ®Google Scholar
• Liu XH, Xu YF, Cui DH, et al. [Association of cyclic adenosine monophosphate response element-binding protein gene and major depressive disorder]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 2010;27(3):263–6.
   PubMedGoogle Scholar
• Wilkie MJ, Smith D, Reid IC, et al. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression. Pharmacogenetics and Genomics 2007;17(3):207–15.
   PubMed Web of Science ®Google Scholar
• Yamada S, Yamamoto M, Ozawa H, et al. Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder. J Neural Transm 2003;110(6):671–80.
   PubMed Web of Science ®Google Scholar
• Zubenko GS, Hughes HB, 3rd, Stiffler JS, et al. Sequence variations in CREB1 cosegregate with depressive disorders in women. Mol Psychiatry 2003;8(6):611–8.
   PubMed Web of Science ®Google Scholar
• Burcescu I, Wigg K, King N, et al. Association study of CREB1 and childhood-onset mood disorders. Am J Med Genet Part B, Neuropsychiatric genetics: the official publication of the International Society of Psychiatric Genetics. 2005;137B(1):45–50.
   Google Scholar