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Original Article

Cerebrovascular events in HIV-infected patients: an analysis of a cohort of 3203 HIV+ patients during the times of cART

, , , , , , , , & show all
Pages 601-611 | Received 23 Apr 2014, Accepted 18 Aug 2014, Published online: 24 Sep 2014

References

  • UNAIDS. UNAIDS Report On The Global AIDS Epidemic. [URL] 2010 [cited 2013 11.16.2013]; Available from: http://www.unaids.org/globalreport/documents/20101123_Glob alReport_full_en.pdf.
  • Hogg R, Lima V, Sterne JA, Grabar S, Battegay M, Bonarek M, D'Arminio Monforte A, Esteve A, Gill MJ, Harris R, Justice A, Hayden A, Lampe F, Mocroft A, Mugavero MJ, Staszewski S, Wasmuth JC, van Sighem A, Kitahata M, Guest J, Egger M, May M. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet 2008 Jul;372(9635):293–9.
  • Pinto AN. AIDS and cerebrovascular disease. Stroke 1996;27(3):538–43.
  • Levy RM, Bredesen DE. Central nervous system dysfunction in acquired immunodeficiency syndrome. J Acquir Immune Defic Syndr 1988;1(1):41–64.
  • McArthur JC. Update on HIV infection. Neurological aspects. Md Med J 1987 Jan;36(1):32–4.
  • Koppel BS, Wormser GP, Tuchman AJ, Maayan S, Hewlett D, Jr., Daras M. Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS). Acta Neurol Scand 1985 May;71(5):337–53.
  • Snider WD, Simpson DM, Nielsen S, Gold JW, Metroka CE, Posner JB. Neurological complications of acquired immune deficiency syndrome: analysis of 50 patients. Ann Neurol 1983 Oct;14(4):403–18.
  • Engstrom JW, Lowenstein DH, Bredesen DE. Cerebral infarctions and transient neurologic deficits associated with acquired immunodeficiency syndrome. Am J Med 1989 May;86(5):528–32.
  • Chow FC, Regan S, Feske S, Meigs JB, Grinspoon SK, Triant VA. Comparison of ischemic stroke incidence in HIV-infected and non-HIV-infected patients in a US health care system. J Acquir Immune Defic Syndr 2012 Aug 1;60(4):351–8.
  • Ovbiagele B, Nath A. Increasing incidence of ischemic stroke in patients with HIV infection. Neurology 2011;76(5):444–50. [http://dx.doi.org/10.1212/WNL.0b013e31820a0cfc]
  • Rasmussen LD, Engsig FN, Christensen H, Gerstoft J, Kronborg G, Pedersen C, Obel N. Risk of cerebrovascular events in persons with and without HIV: A Danish nationwide population-based cohort study. AIDS 2011;25:1637–46.
  • Wang X, Chai H, Yao Q, Chen C. Molecular mechanisms of HIV protease inhibitor-induced endothelial dysfunction. J Acquir Immune Defic Syndr 2007 Apr;44(5):493–9.
  • Francisci D, Giannini S, Baldelli F, Leone M, Belfiori B, Guglielmini G, Malincarne L, Gresele P. HIV type 1 infection, and not short-term HAART, induces endothelial dysfunction. AIDS 2009 Mar;23(5):589–96.
  • Chi D, Henry J, Kelley J, Thorpe R, Smith JK, Krishnaswamy G. The effects of HIV infection on endothelial function. Endothelium 2000;7(4):223–42.
  • Brilla R, Nabavi DG, Schulte-Altedorneburg G, Kemény V, Reichelt D, Evers S, Schiemann U, Husstedt IW. Cerebral vasculopathy in HIV infection revealed by transcranial Doppler: A pilot study. Stroke 1999;30(4):811–3.
  • Kuller LH, Tracy R, Belloso W, De Wit S, Drummond F, Lane HC, Ledergerber B, Lundgren J, Neuhaus J, Nixon D, Paton NI, Neaton JD. Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med 2008 Oct;5(10):e203.
  • Easton JD, Saver JL, Albers GW, Alberts MJ, Chaturvedi S, Feldmann E, Hatsukami TS, Higashida RT, Johnston SC, Kidwell CS, Lutsep HL, Miller E, Sacco RL. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke 2009 Jun;40(6):2276–93.
  • Rabinstein AA. Stroke in HIV-infected patients: a clinical perspective. Cerebrovasc Dis 2003;15(1–2):37–44.
  • Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993;24(1):35–41.
  • Evers S, Nabavi D, Rahmann A, Heese C, Reichelt D, Husstedt I-W. Ischaemic cerebrovascular events in HIV infection: a cohort study. Cerebrovasc Dis 2003;15(3):199–205. [http://dx.doi.org/10.1159/000068828]
  • Dobbs MR, Berger JR. Stroke in HIV infection and AIDS. Expert Rev Cardiovasc Ther 2009;7(10):1263–71. [http://dx.doi.org/10.1586/erc.09.72].
  • d'Arminio Monforte A, Bongiovanni M. Cerebrovascular disease in highly active antiretroviral therapy-treated individuals: incidence and risk factors. J Neurovirol. 2005;11 (Suppl 3):34–7. [http://dx.doi.org/10.1080/13550280500511840]
  • Connor M. Human immunodeficiency virus (HIV) and stroke: targets for intervention. Infect Disord Drug Targets 2010;10(2):76–83.
  • Connor MD, Lammie GA, Bell JE, Warlow CP, Simmonds P, Brettle RD. Cerebral infarction in adult AIDS patients: observations from the Edinburgh HIV Autopsy Cohort. Stroke 2000;31(9):2117–26.
  • Chahine LM, Khoriaty RN, Tomford WJ, Hussain MS. The changing face of neurosyphilis. Int J Stroke 2011 Apr;6(2):136–43.
  • Kieburtz KD, Eskin TA, Ketonen L, Tuite MJ. Opportunistic cerebral vasculopathy and stroke in patients with the acquired immunodeficiency syndrome. Arch Neurol 1993 Apr;50(4):430–2.
  • Anderson AM, Fountain JA, Green SB, Bloom SA, Palmore MP. Human immunodeficiency virus-associated cytomegalovirus infection with multiple small vessel cerebral infarcts in the setting of early immune reconstitution. J Neurovirol 2010;16(2):179–84. [http://dx.doi.org/10.3109/ 13550281003735717].
  • Benjamin LA, Bryer A, Emsley HC, Khoo S, Solomon T, Connor MD. HIV infection and stroke: current perspectives and future directions. Lancet Neurol 2012 Oct;11(10):878–90.
  • Amlie-Lefond C, Jubelt B. Neurologic manifestations of varicella zoster virus infections. Curr Neurol Neurosci Rep 2009 Nov;9(6):430–4.
  • Gutierrez J, Ortiz G. HIV/AIDS patients with HIV vasculopathy and VZV vasculitis: a case series. Clin Neuroradiol 2011 Sep;21(3):145–51.
  • Nagel MA, Cohrs RJ, Mahalingam R, Wellish MC, Forghani B, Schiller A, Safdieh JE, Kamenkovich E, Ostrow LW, Levy M, Greenberg B, Russman AN, Katzan I, Gardner CJ, Hausler M, Nau R, Saraya T, Wada H, Goto H, de Martino M, Ueno M, Brown WD, Terborg C, Gilden DH. The varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features. Neurology 2008 Mar 11;70(11):853–60.
  • Gilden D, Cohrs RJ, Mahalingam R, Nagel MA. Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment. Lancet Neurol 2009 Aug;8(8):731–40.
  • Birlea M, Arendt G, Orhan E, Schmid DS, Bellini WJ, Schmidt C, Gilden D, Cohrs RJ. Subclinical reactivation of varicella zoster virus in all stages of HIV infection. J Neurol Sci 2011 May 15;304(1–2):22–4.
  • Ortiz G, Koch S, Romano JG, Forteza AM, Rabinstein AA. Mechanisms of ischemic stroke in HIV-infected patients. Neurology. 2007;68(16):1257–61. [http://dx.doi.org/10.1212/ 01.wnl.0000259515.45579.1e].
  • Sabin CA, Ryom L, De Wit S, Mocroft A, Phillips AN, Worm SW, Weber R, D'Arminio Monforte A, Reiss P, Kamara D, El-Sadr W, Pradier C, Dabis F, Law M, Lundgren J. Associations between immune depression and cardiovascular events in HIV infection. AIDS 2013 Nov;27(17):2735–48.
  • Singer EJ, Valdes-Sueiras M, Commins DL, Yong W, Carlson M. HIV stroke risk: evidence and implications. Ther Adv Chronic Dis 2013 Mar;4(2):61–70.
  • d'Arminio A, Sabin CA, Phillips AN, Reiss P, Weber R, Kirk O, El-Sadr W, Wit SD, Mateu S, Petoumenos K, Dabis F, Pradier C, Morfeldt L, Lundgren JD, Friis-Møller N, of the D:A:D: Study Group WC. Cardio- and cerebrovascular events in HIV-infected persons. AIDS 2004;18(13):1811–7.
  • Friis-Moller N, Reiss P, Sabin CA, Weber R, Monforte A, El-Sadr W, Thiebaut R, De Wit S, Kirk O, Fontas E, Law MG, Phillips A, Lundgren JD. Class of antiretroviral drugs and the risk of myocardial infarction. N Engl J Med 2007 Apr;356(17):1723–35.
  • Choi AI, Vittinghoff E, Deeks SG, Weekley CC, Li Y, Shlipak MG. Cardiovascular risks associated with abacavir and tenofovir exposure in HIV-infected persons. AIDS 2011 Jun;25(10):1289–98.
  • Sabin CA, Worm SW, Weber R, Reiss P, El-Sadr W, Dabis F, De Wit S, Law M, D'Arminio Monforte A, Friis-Moller N, Kirk O, Pradier C, Weller I, Phillips AN, Lundgren JD. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration. Lancet 2008 Apr;371(9622):1417–26.
  • Bozzette SA, Ake CF, Tam HK, Chang SW, Louis TA. Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. N Engl J Med. 2003;348(8):702–10. [http://dx.doi.org/10.1056/ NEJMoa022048]
  • Corral I, Quereda C, Moreno A, Pérez-Elías M-J, Dronda F, Casado J-L, Muriel A, Masjuán J, de Leciñana MA, Moreno S. Cerebrovascular ischemic events in HIV-1-infected patients receiving highly active antiretroviral therapy: incidence and risk factors. Cerebrovasc Dis. 2009;27(6):559–63. [http://dx.doi.org/10.1159/000214219].
  • Carr A, Samaras K, Chisholm DJ, Cooper DA. Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance. Lancet 1998 Jun;351(9119):1881–3.

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