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Original Articles

Concentration of antiepileptic drugs in persons with epilepsy: a comparative study in serum and saliva

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Pages 972-978 | Received 18 Feb 2015, Accepted 27 Aug 2015, Published online: 06 Oct 2015

References

  • Liamsuwan S, Jaiweerawattana U. Correlation between serum and salivary phenytoin concentrations in Thai epileptic children. J Med Assoc Thail 2011;94(suppl 3):S172–7.
  • Al Za'abi M, Deleu D, Batchelor C. Salivary free concentrations of antiepileptic drugs: an evaluation in routine clinical setting. Acta Neurol Belg 2003;103(1):19–23.
  • Gorodischer R, Burtin P, Verjee Z, et al. Is saliva suitable for therapeutic monitoring of anticonvulsants in children: an evaluation in the routine clinical setting. Ther Drug Monit 1997;19(6):637–42.
  • Liu H, Delgado MR. Therapeutic drug concentration monitoring using saliva samples. Focus on anticonvulsants. Clin Pharmacokinet 1999;36(6):453–70.
  • Patsalos PN, Berry DJ. Therapeutic drug monitoring of antiepileptic drugs by use of saliva. Ther Drug Monit 2013;35(1):4–29.
  • McAuliffe JJ, Sherwin AL, Leppik IE, et al. Salivary levels of anticonvulsants: a practical approach to drug monitoring. Neurology 1977;27(5):409–13.
  • Rosenthal E, Hoffer E, Ben-Aryeh H, et al. Use of saliva in home monitoring of carbamazepine levels. Epilepsia 1995;36(1):72–4.
  • Vasudev A, Tripathi KD, Puri V. Correlation of serum and salivary carbamazepine concentration in epileptic patients: implications for therapeutic drug monitoring. Neurol India 2002;50(1):60–2.
  • Chee KY, Lee D, Byron D, et al. A simple collection method for saliva in children: potential for home monitoring of carbamazepine therapy. Br J Clin Pharmacol 1995;35(3):311–3.
  • Miles MV, Tennison MB, Greenwood RS, et al. Evaluation of the Ames Seralyzer for the determination of carbamazepine, phenobarbital, and phenytoin in saliva. Ther Drug Monit 1990;12(5):501–10.
  • Miles MV, Tennison MB, Greenwood RS. Intra individual variability of carbamazepine, phenobarbital, and phenytoin concentrations in saliva. Ther Drug Monit 1991;13(2):166–71.
  • Nishihara K, Uchino K, Saitoh Y, et al. Estimation of plasma unbound phenobarbital concentration by using mixed saliva. Epilepsia 1979;20(1):37–45.
  • Berg AT, Berkovic SF, Brodie MJ, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005–2009. Epilepsia 2010;51(4):676–85.
  • Dwivedi R, Gupta YK, Singh M, et al. Corre lation of saliva and serum free valproic acid concentrations in persons with epilepsy. Seizure 2014. doi: 10.1016/j.seizure.2014.10.010
  • Nadkarni VV, Dalvi SS, Khare SD. Therapeutic drug monitoring using Rapid High Performance Liquid Chromatographic for simultaneous determination of multiple antiepileptic drugs in human serum: analysis of 45 patients in an epilepsy camp. Neurol Asia 2004;9(suppl 1):120.
  • Sharma S, Joshi S, Mukherji S, et al. Therapeutic drug monitoring: appropriateness and clinical utility in neuropsychiatry practice. Am J Ther. 2009;16(1):11–6.
  • Patsalos PN, Berry DJ, Bourgeois BF, et al. Antiepileptic drugs–best practice guidelines for therapeutic drug monitoring: aposition paper by the Subcommission on Therapeutic Drug Monitoring, ILAE Commission on Therapeutic Strategies. Epilepsia. 2008;49(7):1239–76.
  • Siraslewala S, Malik S, Joshi S, et al. Comparison of salivary versus serum carbamazepine and phenytoin levels in epileptic children. Bombay Hosp J 2008;50(4):572–6.
  • Paxton JW, Donald RA. Concentrations and kinetics of carbamazepine in whole saliva, parotid saliva, serum ultrafiltrate, and serum. Clin Pharmacol Ther 1980;28(5):695–702.
  • Goldsmith RF, Ouvrier RA. Salivary anticonvulsant levels in children: a comparison of methods. Ther Drug Monit 1981;3(2):151–7.
  • Moreland TA, Priestman DA, Rylance GW. Saliva carbamazepine levels in children before and during multiple dosing. Br J Clin Pharmacol 1982;13(5):647–51.
  • Van HG. Comparative study of the levels of anticonvulsants and their free fractions in venous blood, saliva and capillary blood in man. J Pharmacol 1984;15(1):27–35.
  • Knott C, Williams CP, Reynolds F. Phenytoin kinetics during pregnancy and the puerperium. Br J Obstet Gynaecol 1986;93(10):1030–7.
  • Lifshitz M, Ben-Zvi Z, Gorodischer R. Monitoring phenytoin therapy using citric acid-stimulated saliva in infants and children. Ther DrugMonit 1990;12(4):334–8.
  • Schmidt D, Kupferberg H. Diphenylhydantoin, phenobarbital and primidonein saliva, plasma, and cerebrospinal fluid. Epilepsia 1975;16(5):735–41.
  • Knott C, Reynolds F. The place of saliva in antiepileptic drug monitoring. Ther Drug Monit 1984;6(1):35–41.
  • Horning MG, Brown L, Nowlin J, et al. Use of saliva in therapeutic drug monitoring. Clin Chem 1977;23(2):157–64.
  • Friedman IM, Litt IF, Henson R, et al. Saliva phenobarbital and phenytoin concentrations in epileptic adolescents. J Pediatr 1981;98(4):645–7.
  • Luoma PV, Heikkinen JE, Ylostalo PR. Phenobarbital pharmacokinetics and salivary and serum concentrations in pregnancy. Ther Drug Monit 1982;4(1):65–8.
  • Tokugawa K, Ueda K, Fujito H, et al. Correlation between the saliva and free serum concentration of phenobarbitone in epileptic children. Eur J Pediatr 1986;145(5):401–2.
  • Mucklow JC, Bending MR, Kahn GC, et al. Drug concentration in saliva. Clin Pharmacol Ther 1978;24(5):563–70.
  • Bachmann K, Forney RBJ, Voeller K. Monitoring phenytoin salivary and plasma utrafiltrates of pediatric patients. Ther Drug Monit 1983;5(3):325–9.

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