Pineal Grafting and Melatonin Induce Immunocompetence in Nude (Athymic) Mice

References

• Arnason B. G., Jankovic B. D., Waksman B. B., Wennersten C. Role of the thymus in immune reactions in rats. II. Suppressive effect of thymectomy at birth on reactions of delayed (cellular) hypersensitivity and the circulating small lymphocytes. Journal Experimental Medicine 1962; 116: 177–186
   PubMedGoogle Scholar
• Miller J. F. P. A. Immunological function of the thymus. Lancet 1961; 2: 748–749
   PubMed Web of Science ®Google Scholar
• Pierpaoli W., Besedovsky H. O. Role of the thymus in programming of neuroendocrine functions. Clinical & Experimental Immunology 1975; 20: 323–338
   PubMed Web of Science ®Google Scholar
• Pierpaoli W., Kopp H. G., Rianchi E. Interdependence of thymic and neuroendocrine functions in ontogeny. Clinical & Experimental Immunology 1976; 24: 501–506
   PubMedGoogle Scholar
• Pierpaoli W., Sorkin E. Relationship between thymus and hypophysis. Nature 1967; 215: 834–837
   Web of Science ®Google Scholar
• Pierpaoli W., Fabris N., Sorkin E. Developmental hormones and immunological maturation. Hormones and the immune response, G. E.W. Wolstenholme, Julie Night. Churchill, London 1970; 126–143
   Google Scholar
• Pierpaoli W., Baroni C., Fabris N., Sorkin E. Hormones and immunological capacity. II. Reconstitution of antibody production in hormonally deficient mice by somatotropic hormone, thyrotropic hormone and thyroxin. Immunology 1969; 16: 217–230
   PubMed Web of Science ®Google Scholar
• Fabris N., Pierpaoli W., Sorkin E. Hormones and the immunological capacity. IV. Restorative effects of developmental hormones or lymphocytes on the immunodeficiency syndrome of the dwarf mouse. Clinical & Experimental Immunology 1971; 9: 227–240
   PubMedGoogle Scholar
• Pierpaoli W., Sorkin E. Alterations of adrenal cortex and thyroid in mice with congenital absence of the thymus. Nature New Biology 1972; 238: 282–285
   PubMedGoogle Scholar
• Pierpaoli W. Inability of thymus cells from newborn donors to restore transplantation immunity in athymic mice. Immunology 1975; 29: 465–468
   PubMedGoogle Scholar
• Dosch H. M., White D., Grant C. Reconstitution of nude mouse T cell function in vivo: IL-2-independent effect of human T cells. Journal of Immunology 1985; 134: 336–342
   PubMedGoogle Scholar
• Reiter R. J. Interaction of photoperiod, pineal and seasonal reproduction as exemplified by findings in the hamster. The pineal and reproduction, R. J. Reiter. Karger, Basel 1978; 169–190
   Google Scholar
• Pierpaoli W., Dall'Ara A., Pedrinis E., Regelson W. The pineal control of aging. The effects of melatonin and pineal grafting on the survival of older mice. Physiological senescence and its postponement: theoretical approaches and rational interventions. Annals N.Y. Academy Sciences, W. Pierpaoli, N. Fabris. New York Academy of Sciences, New York 1991; Vol. 621: 291–313
   Google Scholar
• Maestroni G., Conti A., Pierpaoli W. Role of the pineal gland in immunity. II. Melatonin enhances the antibody response via an opiatergic mechanism. Clinical & Experimental Immunology 1987; 68: 384–391
   PubMed Web of Science ®Google Scholar
• Vollrath L., Huesgen A., Manz B., Pollok K. Day/night serotonin levels in the pineal gland of male BALB/c mice with melatonin deficiency. Acta Endocrinologica. (Copenh.) 1988; 177: 93–98
   Google Scholar
• Ebihara S., Marks T., Hudson D. J., Menaker M. Genetic control of melatonin synthesis in the pineal gland of the mouse. Science 1986; 231: 491–493
   PubMed Web of Science ®Google Scholar
• Ebihara S., Hudson D. J., Marks T., Menaker M. Pineal indole metabolism in the mouse. Brain Research 1987; 416: 136–144
   PubMedGoogle Scholar
• Groscurth P., Muentener M., Toendury G. Histogenese des Immunsystems der “nude” Maus. II. Postnatale Entwicklung des Thymus: eine lichtmikroskopische Studie. Beitraege zur Pathologic 1975; 154: 125–139
   PubMedGoogle Scholar
• Bulloch K., Pomeranz W. Autonomic nervous system innervation of thymic-related lymphoid tissue in wildtype and nude mice. Journal Comparative Neurology 1984; 228: 57–68
   PubMedGoogle Scholar
• Melatonin rhythm generating system, D. C. Klein. Karger, Basel 1982
   Google Scholar
• Armstrong S. M. Melatonin: the internal Zeitgeber of mammals. Pineal research reviews, R. J. Reiter. Alan R. Liss, New York 1989; Vol. 7: 157–170
   Google Scholar
• Reppert S. M., Weaver D. R., Rivkees S. A., Stopa E. G. Putative melatonin receptors in a human biological clock. Science 1988; 242: 78–81
   PubMed Web of Science ®Google Scholar
• Chronobiology in allergy and immunology, J. P. McGovern, M. H. Smolensky, A. Reinberg. Thomas, Springfield 1977
   Google Scholar
• Abo T., Kawate T., Itoh K., Kumagai K. Studies on the bioperiodicity of the immune response. I. Circadian rhythm of human T, B and K cell traffic in the peripheral blood. Journal of Immunology 1981; 126: 1360–1367
   PubMed Web of Science ®Google Scholar
• Pierpaoli W. Integrated phylogenetic and ontogenetic evolution of neuroendocrine and identity-defence, immune functions. Psychoneuroimmunology, R. Ader. Academic Press, New York 1981; 575–606
   Google Scholar
• Maestroni G., Pierpaoli W. Pharmacological control of the hormonally mediated immune response. Psychoneuroimmunology, R. Ader. Academic Press, New York 1981; 405–428
   Google Scholar
• Weinstein Y. 20a-hydmxysteroid-dehydrogenase: a T lymphocyte associated enzyme. Journal of Immunology 1977; 119: 1223–1229
   PubMed Web of Science ®Google Scholar
• Cardinali D. P., Vacas M. Mechanisms underlying hormone effects on pineal function: a model for the study of integrative neuroendocrine processes. Journal of Endocrinological Investigation 1978; 1: 87–94
   Google Scholar
• Barraclough C. A. Handbook of physiology & endocrinology. American Physiological Society, Washington 1973; Vol. 2: 29–54, part I
   Google Scholar
• Piantelli M., Carbone A., Lauriola L., Musiani P., Ranelletti F. O. (1984) XII National Conference Italian. 1984. Immunology Cooperation Group, CortonaItaly, (Abstract)
   Google Scholar
• Blalock J. E. The immune system as a sensory organ. Journal of Immunology 1984; 132: 1067–1070
   PubMed Web of Science ®Google Scholar