Y chromosome loss is a frequent early event in urothelial bladder cancer

References

• Holmang S, Hedelin H, Anderstrom C, Holmberg E, Busch C, Johansson SL. Recurrence and progression in low grade papillary urothelial tumors. J Urol 1999; 162: 702–707.
   PubMed Web of Science ®Google Scholar
• Stein JP, Lieskovsky G, Cote R, et al Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001; 19: 666–675.
   PubMed Web of Science ®Google Scholar
• Fadl-Elmula I, Gorunova L, Mandahl N, et al Karyotypic characterization of urinary bladder transitional cell carcinomas. Genes Chromosomes Cancer 2000; 29: 256–265.
   PubMed Web of Science ®Google Scholar
• Panani AD, Roussos C. Sex chromosome abnormalities in bladder cancer: Y polysomies are linked to PT1-grade III transitional cell carcinoma. Anticancer Res 2006; 26: 319–323.
   PubMed Web of Science ®Google Scholar
• Sauter G, Moch H, Mihatsch MJ, Gasser TC. Molecular cytogenetics of bladder cancer progression. Eur Urol 1998; 33 (Suppl 4): 9–10.
   PubMed Web of Science ®Google Scholar
• Smeets W, Pauwels R, Laarakkers L, Debruyne F, Geraedts J. Chromosomal analysis of bladder cancer. III. Nonrandom alterations. Cancer Genet Cytogenet 1987; 29: 29–41.
   PubMedGoogle Scholar
• Sauter G, Gasser TC, Moch H, et al DNA aberrations in urinary bladder cancer detected by flow cytometry and FISH. Urol Res 1997; 25 (Suppl 1): S37–S43.
   Google Scholar
• Sauter G, Moch H, Wagner U, et al Y chromosome loss detected by FISH in bladder cancer. Cancer Genet Cytogenet 1995; 82: 163–169.
   PubMedGoogle Scholar
• Neuhaus M, Wagner U, Schmid U, et al Polysomies but not Y chromosome losses have prognostic significance in pTa/pT1 urinary bladder cancer. Hum Pathol 1999; 30: 81–86.
   PubMed Web of Science ®Google Scholar
• Powell I, Tyrkus M, Kleer E. Apparent correlation of sex chromosome loss and disease course in urothelial cancer. Cancer Genet Cytogenet 1990; 50: 97–101.
   PubMedGoogle Scholar
• Wild PJ, Kunz-Schughart LA, Stoehr R, et al High-throughput tissue microarray analysis of COX2 expression in urinary bladder cancer. Int J Oncol 2005; 27: 385–391.
   PubMed Web of Science ®Google Scholar
• Bubendorf L. High-throughput microarray technologies: from genomics to clinics. Eur Urol 2001; 40: 231–238.
   PubMed Web of Science ®Google Scholar
• Mostofi F, Sobin L, Torloni H. Histological Typing of Urinary Bladder Tumors. International Classification of Tumors. 10th ed. Geneva: World Health Organization, 1973.
   Google Scholar
• UICC. Classification of Malignant Tumors. 4th ed. Berlin: Springer, 1992.
   Google Scholar
• Brunelli M, Eble JN, Zhang S, Martignoni G, Cheng L. Gains of chromosomes 7, 17, 12, 16, and 20 and loss of Y occur early in the evolution of papillary renal cell neoplasia: a fluorescent in situ hybridization study. Mod Pathol 2003; 16: 1053–1059.
   PubMed Web of Science ®Google Scholar
• Poetsch M, Kleist B, Lorenz G, Herrmann FH. Different numerical chromosomal aberrations detected by FISH in oropharyngeal, hypopharyngeal and laryngeal squamous cell carcinoma. Histopathology 1999; 34: 234–240.
   PubMed Web of Science ®Google Scholar
• Szyfter K, Szmeja Z, Szyfter W, et al Molecular and cellular alterations in tobacco smoke-associated larynx cancer. Mutat Res 1999; 445: 259–274.
   PubMed Web of Science ®Google Scholar
• Walch AK, Zitzelsberger HF, Bruch J, et al Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence. Am J Pathol 2000; 156: 555–566.
   PubMed Web of Science ®Google Scholar
• Hunter S, Gramlich T, Abbott K, Varma V. Y chromosome loss in esophageal carcinoma: an in situ hybridization study. Genes Chromosomes Cancer 1993; 8: 172–177.
   PubMed Web of Science ®Google Scholar
• van Dekken H, Alers JC, Riegman PH, Rosenberg C, Tilanus HW, Vissers K. Molecular cytogenetic evaluation of gastric cardia adenocarcinoma and precursor lesions. Am J Pathol 2001; 158: 1961–1967.
   PubMed Web of Science ®Google Scholar
• Kowalski J, Morsberger LA, Blackford A, et al Chromosomal abnormalities of adenocarcinoma of the pancreas: identifying early and late changes. Cancer Genet Cytogenet 2007; 178: 26–35.
   PubMedGoogle Scholar
• Bottarelli L, Azzoni C, Necchi F, et al Sex chromosome alterations associate with tumor progression in sporadic colorectal carcinomas. Clin Cancer Res 2007; 13: 4365–4370.
   PubMed Web of Science ®Google Scholar
• Herens C, Brasseur E, Jamar M, Vierset L, Schoenen I, Koulischer L. Loss of the Y chromosome in bone marrow cells: results on 1907 consecutive cases of leukaemia and preleukaemia. Clin Lab Haematol 1999; 21: 17–20.
   PubMedGoogle Scholar
• Zhang LJ, Shin ES, Yu ZX, Li SB. Molecular genetic evidence of Y chromosome loss in male patients with hematological disorders. Chin Med J (Engl) 2007; 120: 2002–2005.
   PubMed Web of Science ®Google Scholar
• Guttenbach M, Koschorz B, Bernthaler U, Grimm T, Schmid M. Sex chromosome loss and aging: in situ hybridization studies on human interphase nuclei. Am J Hum Genet 1995; 57: 1143–1150.
   PubMed Web of Science ®Google Scholar
• Betz J, Meloni AM, Sandberg AA. FISH studies on the Y chromosome in male urinary cells. Cancer Genet Cytogenet 1996; 88: 155–157.
   PubMedGoogle Scholar
• United Kingdom Cancer Cytogenetics Group (UKCCG). Loss of the Y chromosome from normal and neoplastic bone marrows. Genes Chromosomes Cancer 1992; 5: 83–88.
   PubMed Web of Science ®Google Scholar
• Ensembl Genome Browser: Chromosome Y: 59,323,567-59,373,566. Available at: http://www.ensembl.org/Homo_sapiens/Location/Chromosome?r=Y:59323567-59423567 (accessed February 2010).
   Google Scholar