Loss of Raf-1 kinase inhibitory protein in pancreatic ductal adenocarcinoma

References

• Jung KW, Won YJ, Park S, et al Cancer statistics in Korea: incidence, mortality and survival in 2005. J Korean Med Sci 2009; 24: 995–1003.
   PubMed Web of Science ®Google Scholar
• Bassi C, Falconi M, Salvia R, Mascetta G, Molinari E, Pederzoli P. Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patients. Dig Surg 2001; 18: 453–7; discussion 8.
   PubMed Web of Science ®Google Scholar
• Ryska M, Strnad R, Belina F, et al Radical resection in patients with pancreatic head carcinomas. A retrospective survival analysis in a group of 307 subjects. (Czech). Rozhl Chir 2007; 86: 432–9.
   PubMedGoogle Scholar
• Chen Y, Ouyang GL, Yi H, et al Identification of RKIP as an invasion suppressor protein in nasopharyngeal carcinoma by proteomic analysis. J Proteome Res 2008; 7: 5254–62.
   PubMed Web of Science ®Google Scholar
• Hagan S, Al-Mulla F, Mallon E, et al Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis. Clin Cancer Res 2005; 11: 7392–7.
   PubMed Web of Science ®Google Scholar
• Fu Z, Kitagawa Y, Shen R, et al Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer. Prostate 2006; 66: 248–56.
   PubMed Web of Science ®Google Scholar
• Fu Z, Smith PC, Zhang L, et al Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst 2003; 95: 878–89.
   PubMed Web of Science ®Google Scholar
• Li HZ, Wang Y, Gao Y, et al Effects of raf kinase inhibitor protein expression on metastasis and progression of human epithelial ovarian cancer. Mol Cancer Res 2008; 6: 917–28.
   PubMed Web of Science ®Google Scholar
• Li HZ, Gao Y, Zhao XL, et al Effects of raf kinase inhibitor protein expression on metastasis and progression of human breast cancer. Mol Cancer Res 2009; 7: 832–40.
   PubMed Web of Science ®Google Scholar
• Perry AC, Hall L, Bell AE, Jones R. Sequence analysis of a mammalian phospholipid-binding protein from testis and epididymis and its distribution between spermatozoa and extracellular secretions. Biochem J 1994; 301 (Pt 1): 235–42.
   PubMedGoogle Scholar
• Serre L, Pereira de Jesus K, Zelwer C, Bureaud N, Schoentgen F, Benedetti H. Crystal structures of YBHB and YBCL from Escherichia coli, two bacterial homologues to a Raf kinase inhibitor protein. J Mol Biol 2001; 310: 617–34.
   PubMedGoogle Scholar
• Yeung K, Seitz T, Li S, et al Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP. Nature 1999; 401: 173–7.
   PubMed Web of Science ®Google Scholar
• Hoshino R, Chatani Y, Yamori T, et al Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 1999; 18: 813–22.
   PubMed Web of Science ®Google Scholar
• Mueller H, Flury N, Eppenberger-Castori S, Kueng W, David F, Eppenberger U. Potential prognostic value of mitogen-activated protein kinase activity for disease-free survival of primary breast cancer patients. Int J Cancer 2000; 89: 384–8.
   PubMed Web of Science ®Google Scholar
• Krueger JS, Keshamouni VG, Atanaskova N, Reddy KB. Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion. Oncogene 2001; 20: 4209–18.
   PubMed Web of Science ®Google Scholar
• Hruban RH, van Mansfeld AD, Offerhaus GJ, et al K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am J Pathol 1993; 143: 545–54.
   PubMed Web of Science ®Google Scholar
• Marais R, Marshall CJ. Control of the ERK MAP kinase cascade by Ras and Raf. Cancer Surv 1996; 27: 101–25.
   PubMedGoogle Scholar
• Kajanne R, Miettinen P, Mehlem A, et al EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways. J Cell Physiol 2007; 212: 489–97.
   PubMed Web of Science ®Google Scholar
• McCawley LJ, Li S, Wattenberg EV, Hudson LG. Sustained activation of the mitogen-activated protein kinase pathway. A mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase-9 induction and cell migration. J Biol Chem 1999; 274: 4347–53.
   PubMed Web of Science ®Google Scholar
• Klemke RL, Cai S, Giannini AL, Gallagher PJ, de Lanerolle P, Cheresh DA. Regulation of cell motility by mitogen-activated protein kinase. J Cell Biol 1997; 137: 481–92.
   PubMed Web of Science ®Google Scholar
• Kim HS, Kim GY, Lim SJ, Park YK, Kim YW. Reduced expression of Raf-1 kinase inhibitory protein is a significant prognostic marker in patients with gallbladder carcinoma. Hum Pathol 2010; Aug 3: (Epub ahead of print).
   Google Scholar
• Kim HS, Kim GY, Lim SJ, Kim YW. Expression of Raf-1 kinase inhibitory protein in extrahepatic bile duct carcinoma. Korean J Pathol 2010; 44: 234–42.
   Google Scholar
• Minoo P, Zlobec I, Baker K, et al Loss of raf-1 kinase inhibitor protein expression is associated with tumor progression and metastasis in colorectal cancer. Am J Clin Pathol 2007; 127: 820–7.
   PubMed Web of Science ®Google Scholar
• Wang J, Yang YH, Wang AQ, et al Immunohistochemical detection of the Raf kinase inhibitor protein in nonneoplastic gastric tissue and gastric cancer tissue. Med Oncol 2010; 27: 219–23.
   PubMedGoogle Scholar
• Al-Mulla F, Hagan S, Al-Ali W, et al Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability. J Clin Pathol 2008; 61: 524–9.
   PubMed Web of Science ®Google Scholar
• Al-Mulla F, Hagan S, Behbehani AI, et al Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients. J Clin Oncol 2006; 24: 5672–9.
   PubMed Web of Science ®Google Scholar
• Barnes DM, Harris WH, Smith P, Millis RR, Rubens RD. Immunohistochemical determination of oestrogen receptor: comparison of different methods of assessment of staining and correlation with clinical outcome of breast cancer patients. Br J Cancer 1996; 74: 1445–51.
   PubMed Web of Science ®Google Scholar
• Schuierer MM, Bataille F, Hagan S, Kolch W, Bosserhoff AK. Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res 2004; 64: 5186–92.
   PubMed Web of Science ®Google Scholar
• Chatterjee D, Sabo E, Tavares R, Resnick MB. Inverse association between Raf Kinase Inhibitory Protein and signal transducers and activators of transcription 3 expression in gastric adenocarcinoma patients: implications for clinical outcome. Clin Cancer Res 2008; 14: 2994–3001.
   Google Scholar
• Lee HC, Tian B, Sedivy JM, Wands JR, Kim M. Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells. Gastroenterology 2006; 131: 1208–17.
   PubMed Web of Science ®Google Scholar
• Peraldi P, Frodin M, Barnier JV, et al Regulation of the MAP kinase cascade in PC12 cells: B-Raf activates MEK-1 (MAP kinase or ERK kinase) and is inhibited by cAMP. FEBS Lett 1995; 357: 290–6.
   PubMed Web of Science ®Google Scholar
• Calhoun ES, Jones JB, Ashfaq R, et al BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets. Am J Pathol 2003; 163: 1255–60.
   PubMed Web of Science ®Google Scholar
• Trakul N, Menard RE, Schade GR, Qian Z, Rosner MR. Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. J Biol Chem 2005; 280: 24931–40.
   PubMed Web of Science ®Google Scholar
• Ehlers RA, Zhang Y, Hellmich MR, Evers BM. Neurotensin-mediated activation of MAPK pathways and AP-1 binding in the human pancreatic cancer cell line, MIA PaCa-2. Biochem Biophys Res Commun 2000; 269: 704–8.
   PubMedGoogle Scholar
• Todisco A, Takeuchi Y, Urumov A, Yamada J, Stepan VM, Yamada T. Molecular mechanisms for the growth factor action of gastrin. Am J Physiol 1997; 273: G891–8.
   Google Scholar
• Duan RD, Williams JA. Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini. Am J Physiol 1994; 267: G401–8.
   Google Scholar
• Tateishi K, Funakoshi A, Misumi Y, Matsuoka Y. Jun and MAP kinases are activated by cholecystokinin in the pancreatic carcinoma cell line KP-1N. Pancreas 1998; 16: 499–504.
   PubMedGoogle Scholar
• Schuierer MM, Bataille F, Weiss TS, Hellerbrand C, Bosserhoff AK. Raf kinase inhibitor protein is downregulated in hepatocellular carcinoma. Oncol Rep 2006; 16: 451–6.
   PubMed Web of Science ®Google Scholar
• Beach S, Tang H, Park S, et al Snail is a repressor of RKIP transcription in metastatic prostate cancer cells. Oncogene 2008; 27: 2243–8.
   PubMed Web of Science ®Google Scholar
• Sato N, Fukushima N, Hruban RH, Goggins M. CpG island methylation profile of pancreatic intraepithelial neoplasia. Mod Pathol 2008; 21: 238–44.
   PubMed Web of Science ®Google Scholar
• Ueki T, Toyota M, Sohn T, et al Hypermethylation of multiple genes in pancreatic adenocarcinoma. Cancer Res 2000; 60: 1835–9.
   PubMed Web of Science ®Google Scholar
• Yin T, Wang C, Liu T, Zhao G, Zha Y, Yang M. Expression of snail in pancreatic cancer promotes metastasis and chemoresistance. J Surg Res 2007; 141: 196–203.
   PubMed Web of Science ®Google Scholar
• Hotz B, Arndt M, Dullat S, Bhargava S, Buhr HJ, Hotz HG. Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer. Clin Cancer Res 2007; 13: 4769–76.
   PubMed Web of Science ®Google Scholar