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Original Article

Controlled Pore Glass Factor VIII Concentrate: Influence of Heat Treatment

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Pages 56-57 | Accepted 25 Jun 1986, Published online: 06 Jul 2009

References

  • Melbye M, Madhok R, Savin P S, et al. HTLV-III seropositivity in European haemophiliacs exposed to factor VIII concentrate imported from the USA. Lancet 1984; ii: 1444–6
  • Evatt B L, Gomperts E D, McDougal J S, Ramsey R B. Coincidental appearance of LAV/HTLV-III antibodies in hemophiliacs and the onset of the AIDS epidemic. N Engl J Med 1985; 312: 483–6
  • Levy J A, Mitra G, Mozen M M. Recovery and inactivation of infectious retroviruses added to factor VIII concentrates. Lancet 1984; ii: 722–3
  • Editorial. Recommendations concerning AIDS and the treatment of hemophilia. American Blood Resources Association, Newsletter, Annapolis, Maryland October, 1984
  • Margolis J, Rhoades P H. Preparation of high purity factor VIII by controlled pore glass chromatography. Lancet 1981; ii: 446–8
  • Benny A G, Scott R H, Woodfield D G. Preparation of a factor VIII concentrate by controlled pore glass adsorption chromatography. Transfusion 1986, in press
  • McGrath K M, Thomas K B, Herrington R W, et al. Use of heat treated clotting factor concentrates in patients with haemophilia and a high exposure to HTLV-III. Med J Aust 1985; 143: 11–3
  • Chantarangkul V, Ingram G IC, Thorn M B, Darby S C. An artificial 'haemophilic plasma for one-stage factor VIII assay. Brit J Haematol 1978; 40: 471–88
  • International Committee for Standardisation in Haematology. Standard techniques for the measurement of red cell and plasma volume. Brit J Haematol 1973; 25: 801–15
  • Ockelford P A, Lowe G, Johns A S, Berry E W. Comparison of methods of plasma volume determination for dose calculation of factor VIII in patients with classic haemophilia. NZ Med J 1986; 99: 116–9
  • Abildgaard C F, Cornet J A, Fort E, Schulman I. The in vivo longevity of antihaemophilic factor (factor VIII). Brit J Haematol 1964; 10: 225–37
  • Evatt B L. AIDS. Proceedings XXIst International Congress for Haematology. May, 1986
  • Rouzioux C, Chamaret S, Montagnier, et al. Absence of antibodies to the AIDS virus in haemophiliacs treated with heat treated factor VIII concentrate. Lancet 1985; 1: 271–2
  • McDougal J S, Martin L S, Cort S P, et al. Thermal inactivation of the acquired immunodeficiency syndrome virus, HTLV-III/LAV, with special reference to antihaemophilic factor. J Clin Invest 1985; 76: 875–7

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