352
Views
4
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Interference of common haemoglobin variants with the Tosoh G7 standard mode HbA1c method

, , &
Pages 362-366 | Received 13 May 2014, Accepted 17 Mar 2015, Published online: 10 Apr 2015

References

  • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977–86.
  • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837–53.
  • International Expert Committee. International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care 2009;32:1327–34.
  • American Diabetes Association. Executive summary: Standards of medical care in diabetes – 2012. Diabetes Care 2012;35(Suppl. 1):S4–10.
  • World Health Organization (WHO). Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes mellitus. Accessed 3 July 2012 from: http://www.who.int/diabetes/publications/report-hba1c_2011.pdf
  • Kutter D, Thoma J. Hereditary spherocytosis and other hemolytic anomalies distort diabetic control by glycated hemoglobin. Clin Lab 2006;52:477–81.
  • Lin CN, Emery TJ, Little RR, Hanson SE, Rohlfing CL, Jaisson S, Gillery P, Roberts WL. Effects of hemoglobin C, D, E, and S traits on measurements of HbA1c by six methods. Clin Chim Acta 2012;413:819–21.
  • Little RR, Roberts WL. A review of variant hemoglobins interfering with hemoglobin A1c measurement. J Diabetes Sci Technol 2009;3:446–51.
  • Little RR, Rohlfing CL, Hanson SE, Roberts WL. Effects of hemoglobin C and S traits on Tosoh G8 and Siemens Advia HbA1c assays. Clin Chim Acta 2010;411:779–80.
  • Little RR, Rohlfing CL, Hanson SE, Schmidt RL, Lin CN, Madsen RW, Roberts WL. The effect of increased fetal hemoglobin on 7 common Hb A1c assay methods. Clin Chem 2012;58:945–7.
  • Roberts WL, Safar-Pour S, De BK, Rohlfing CL, Weykamp CW, Little RR. Effects of hemoglobin C and S traits on glycohemoglobin measurements by eleven methods. Clin Chem 2005;51:776–8.
  • Mongia SK, Little RR, Rohlfing CL, Hanson S, Roberts RF, Owen WE, D’Costa MA, Reyes CA, Luzzi VI, Roberts WL. Effects of hemoglobin C and S traits on the results of 14 commercial glycated hemoglobin assays. Am J Clin Pathol 2008;130:136–40.
  • Rohlfing CL, Connolly SM, England JD, Hanson SE, Moellering CM, Bachelder JR, Little RR. The effect of elevated fetal hemoglobin on hemoglobin A1c results: five common hemoglobin A1c methods compared with the IFCC reference method. Am J Clin Pathol 2008;129:811–4.
  • Shu I, Devaraj S, Hanson SE, Little RR, Wang P. Comparison of hemoglobin A1c measurements of samples with elevated fetal hemoglobin by three commercial assays. Clin Chim Acta 2012;413:1712–3.
  • Jaisson S, Leroy N, Desroches C, Tonye-Libyh M, Guillard E, Gillery P. Interference of the most frequent haemoglobin variants on quantification of HbA1c: comparison between the LC-MS (IFCC reference method) and three routinely used methods. Diabetes Metab 2013;39:363–9.
  • Little RR, Rohlfing CL, Hanson S, Connolly S, Higgins T, Weykamp CW, D’Costa M, Luzzi V, Owen WE, Roberts WL. Effects of hemoglobin (Hb) E and HbD traits on measurements of glycated Hb (HbA1c) by 23 methods. Clin Chem 2008;54:1277–82.
  • Bhat VS, Dewan KK, Krishnaswamy PR. Diagnostic dilemma of HbA1c detection in presence of a hemoglobinopathy: a case report. Indian J Clin Biochem 2011; 26:91–5.
  • Bisse E, Hovasse A, Preisler-Adams S, Epting T, Wagner O, Kogel G, Van DA, Schaeffer-Reiss C. Hb Riesa or beta93 (F9) Cys–> Ser, a new electrophoretically silent haemoglobin variant interfering with haemoglobin A1c measurement. J Chromatogr B Analyt Technol Biomed Life Sci 2011;879:2952–6.
  • del Rey TH, Conde-Sanchez M, Ropero-Gradilla P, Dominguez-Pascual I, Gonzalez-Fernandez FA, Villegas A, Guerrero JM. Hemoglobin Seville [alpha2 beta2 81(EF5) Leu–> Phe] a silent phenotypic variant that interferes in hemoglobin A1c measurement by ion-exchange HPLC method. Clin Biochem 2011;44:933–5.
  • Chen CF, Chien CM, Liu SC, Tai YK. A rare hemoglobin variant (Hb Iraq-Halabja) causing spuriously low hemoglobin A1c values. Intern Med 2013;52:2443–6.
  • Lee SC, Wang LH, Tsai SM, Fang HY, Tsai LY. Effects of the Hb E, Hb H and Hb G-Taichung variants on HbA1c values by the Bio-Rad variant II turbo analyzer. Clin Biochem 2011;44:1338–42.
  • Grimholt RM, Sudmann AA, Piehler AP, Urdal P, Klingenberg O. Hb Ullevaal [beta78(EF2)Leu–> Val; HBB: c.235C> G], a new hemoglobin variant interfering with Hb A1c measurement using a cation exchange high performance liquid chromatography method. Hemoglobin 2014; 38(2):130–2.
  • Molina-Arrebola MA, Sanchez-Crespo A, Gimenez Lopez MJ, Estevez-Escobar M, Garcia-Bautista JA, Perez-Moyano R, Salas-Coronas J, Avivar-Oyonarte C. Haemoglobin Kenitra detected by HPLC assay and its compromising effect on the measurement of HbA1c. Int J Lab Hematol 2013;35: e18–20.
  • Piehler AP, Grimholt RM, Bjerner J, Urdal P, Buchmann M. Discrepancy between HbA1c and fasting glucose results due to HbD. Scand J Clin Lab Invest 2013;73:186–8.
  • National Glycohemoglobin Standardization Program. NGSP certified methods. Accessed 30 January 2014 from: http://www.ngsp.org/certified.asp
  • Williams TN, Weatherall DJ. World distribution, population genetics, and health burden of the hemoglobinopathies. Cold Spring Harb Perspect Med 2012;2:a011692.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.