260
Views
18
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Elevated levels of Th17 cells in children with central obesity

, , , &
Pages 595-601 | Received 13 Nov 2014, Accepted 10 May 2015, Published online: 28 Jul 2015

References

  • Bac A, Woźniacka R, Matusik S, Golec J, Golec E. Prevalence of overweight and obesity in children aged 6–13 years – alarming increase in obesity in Cracow, Poland. Eur J Pediatr 2012;171:245–51.
  • Tateya S, Kim F, Tamori Y. Recent advances in obesity- induced inflammation and insulin resistance. Front Endocrinol 2013;8:93.
  • Jarosz-Chobot P, Polanska J, Szadkowska A, Kretowski A, Bandurska-Stankiewicz E, Ciechanowska M, Deja G, Mysliwiec M, Peczynska J, Rutkowska J, Sobel-Maruniak A, Fichna P, Chobot A, Rewers M. Rapid increase in the incidence of type 1 diabetes in Polish children from 1989 to 2004, and predictions for 2010 to 2025. Diabetologia 2011;54:508–15.
  • Bluestone JA, Herold K, Eisenbarth G. Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature 2010;464:1293–300.
  • Hu Y, Shen F, Crellin NK, Ouyang W. The IL-17 pathway as a major therapeutic target in autoimmune diseases. Ann NY Acad Sci 2011;1217.
  • Marwaha AK, Leung NJ, McMurchy AN, Levings MK. Th17 cells in autoimmunity and immunodeficiency: protective or pathogenic ? Front Immunol 2012;3:129.
  • Wu CC, Sytwu HK, Lin YF. Cytokines in diabetic nephropathy. Adv Clin Chem 2012;56:55–74.
  • Fabbrini E, Cella M, McCartney SA, Fuchs A, Abumrad NA, Pietka TA, Chen Z, Finck BN, Han DH, Magkos F, Conte C, Bradley D, Fraterrigo G, Eagon JC, Patterson BW, Colonna M, Klein S. Association between specific adipose tissue CD4 + T-cell populations and insulin resistance in obese individuals. Gastroenterology 2013;145:366–74.
  • Kułaga Z, Litwin M, Zajączkowska MM, Wasilewska A, Morawiec-Knysak A, Różdżyńska A, Grajda A, Gurzkowska B, Napieralska E, Barwicka K, Świąder S. Porównanie wartości obwodów talii i bioder dzieci i młodzieży polskiej w wieku 7-18 lat z wartościami referencyjnymi dla oceny ryzyka sercowo-naczyniowego - wyniki wstępne projektu badawczego OLAF (PL0080) (Comparison of waist and hip circumferences ranges in children and adolescents in Poland 7–18 y of age with cardiovascular risk thresholds – initial results of OLAF project (PL0080)). Stand Med 2008;5:473–85.
  • Kułaga Z, Różdżyńska A, Palczewska I, Grajda A, Gurzkowska B, Napieralska E, Litwin M. Siatki centylowe wysokości, masy ciała i wskaźnika masy ciała dzieci i młodzieży w Polsce - wyniki badania OLAF. (Percentile charts of height, body mass and body mass index in children and adolescents in Poland – results of the OLAF study.) Stand Med Ped 2010;7:690–700.
  • Kułaga Z, Litwin M, Grajda A, Gurzkowska B, Napieralska E, Kułaga K. Rozkłady wartości ciśnienia krwi w populacji referencyjnej dzieci i młodzieży w wieku szkolnym. (Distribution of blood pressure in school-aged children and adolescents reference population.) Stand Med Ped 2010; 7:100–11.
  • Winer S, Paltser G, Chan Y, Tsui H, Engleman E, Winer D, Dosch HM. Obesity predisposes to Th17 bias. Eur J Immunol 2009;39:2629–35.
  • Zhao R, Tang D, Yi S, Li W, Wu C, Lu Y, Hou X, Song J, Lin P, Chen L, Sun L. Elevated peripheral frequencies of Th22 cells: a novel potent participant in obesity and type 2 diabetes. PLoS One 2014;9:e85770.
  • Sumarac-Dumanovic M, Stevanovic D, Ljubic A, Jorga J, Simic M, Stamenkovic-Pejkovic D, Starcevic V, Trajkovic V, Micic D. Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women. Int J Obes (Lond) 2009;33:151–6.
  • Bertola A, Ciucci T, Rousseau D, Bourlier V, Duffaut C, Bonnafous S, Blin-Wakkach C, Anty R, Iannelli A, Gugenheim J, Tran A, Bouloumie A, Gual P, Wakkach A. Identification of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 response in mice and patients. Diabetes 2012;61: 2238–47.
  • Goswami J, Hernandez-Santos N, Zuniga LA, Gaffen SL. A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss. Eur J Immunol 2009;39: 2831–9.
  • Taleb S, Tedgui A, Mallat Z. Interleukin-17: friend or foe in atherosclerosis? Curr Opin Lipidol 2010;21:404–8.
  • Zhang C, Xiao C, Wang P, Xu W, Zhang A, Li Q, Xu X. The alterations of Th1/Th2/Th17/Treg paradigm in patients with type 2 diabetes mellitus: relationship with diabetic nephropathy. Hum Immunol 2014;75:289–96.
  • Ryba-Stanisławowska M, Skrzypkowska M, Myśliwiec M, Myśliwska J. Loss of the balance between CD4(+)FoxP3(+) regulatory T cells and CD4(+)IL17A(+) Th17 cells in patients with type 1 diabetes. Hum Immunol 2013;74: 701–7.
  • Han XQ, Gong ZJ, Xu SQ, Li X, Wang LK, Wu SM, Wu JH, Yang FF. Advanced glycation end products promote differentiation of CD4(+) T helper cells toward pro-ifnalmmatory response. J Huazhong Univ Sci Technolog Med Sci 2014;34:10–7.
  • Martinez PJ, Mathews C, Actor JK, Hwang SA, Brown EL, De Santiago HK, Fisher Hoch SP, McCormick JB, Mirza S. Impaired CD4 + and T-helper 17 cell memory response to Streptococcus pneumoniae is associated with elevated glucose and percent glycated hemoglobin A1c in Mexican Americans with type 2 diabetes mellitus. Transl Res 2014;163:53–63.
  • Monk JM, Hou TY, Turk HF, Weeks B, Wu C, McMurray DN, Chapkin RS. Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis. PLoS One 2012;7:e49739.
  • Zhao Y, Yang L, Wang X, Zhou Z. The new insight of DPP-4 inhibitors: their potential immune modulatory function in autoimmune diabetes. Diabetes Metab Res Rev 2014;30: 646–53.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.