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Original Article

Determination of Phenobarbital in Serum in the Presence of other Barbiturates, Sulphonamides, Salicylates, and other Interfering Drugs

Pages 109-112 | Received 01 May 1967, Published online: 08 Jul 2009

References

  • Goldbaum L. R. An ultraviolet spectrophotometric procedure for determination of barbiturates. J. Pharmacol. exp. Ther. 1948; 94: 68
  • Lous P. Determination of barbiturates; a modified spectrophotometric method for clinical use. Acta pharmacol. (Kbh.) 1950; 6: 227
  • Morrison J. C., Chatten L. G. Estimation of barbiturates by quantitative thin-layer chromatography. J. Pharmacol. exp. Ther. 1965; 17: 655
  • Olesen O. V. A simplified method for extracting phenytoin from serum, and a more sensitive staining reaction for quantitative determination by thinlayer chromatography. Acta pharmacol. (Kbh.) 1967a; 25: 123
  • Olesen O. V. Determination of phenobarbital and phenytoin in serum by ultraviolet spectrophotometry. Scand. J. clin. Lab. Invest. 1967; 20: 63
  • Olesen O. V., Dam M. The metabolic conversion of primidonum (Mysoline®) to phenobarbital in patients under long term treatment. Acta neurol. scand. 1967, In press.
  • Svensmark O., Kristensen P. Determination of diphenylhydantoin and phenobarbital in small amounts of serum. J. Lab. clin. Med. 1963; 61: 501

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