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Original Article

Ultrafiltration devices tested for use in a free thyroxine assay validated by comparison with equilibrium dialysis

Pages 663-669 | Received 27 Oct 1989, Accepted 23 Mar 1990, Published online: 08 Jul 2009

References

  • Ekins R P, Ellis S M. The radioimmunoassay of free thyroid hormones in serum. Thyroid Research, Proc Seventh Int Thyroid Cok, L E Braverman, J Robbins. Excerpta Medica, Amsterdam 1976; 597–600, Boston, 1975
  • Weeke J, Ourskov H. Ultrasensitive radioimmunoassay for direct determination of free triiodothyronine concentration in serum. Scand J Clin Lab Invest 1975; 35: 237–44
  • Helenius T, Liewendahl K. Improved dialysis method for free thyroxin in serum compared with five commercial radioimmunoassays in non-thyroidal illness and subjects with abnormal concentrations of thyroxin-binding globulin. Clin Chem 1983; 29: 816–22
  • Midgley J EM, Winton M RJ, Wilkins T A. Relationship between effects of added albumin, initial free thyroxine value and endogenous serum-binding protein concentrations on Amerlex® free thyroxine estimations. Clin Chim Acta 1987; 167: 67–79
  • Kubasik N P, Lundberg P-A, Brodows R G, Hallauer G D, Same D G, Lindstedt G, Bcngtsson C, Nystrom E. Free thyroxin by radioimmunoassay: evaluation of a new direct method involving a radiolabeled thyroxin analog. Clin Chem 1983; 29: 1781–6
  • Witherspoon L R, El Shami A S, Shuler S E, Neely H, Sonnemaker R, Gilbert S S, Alyea K. Chemically blocked analog assays for free thyronines. II. Use of equilibrium dialysis to optimize the displacement by chemical blockers of T4 analog and T, analog from albumin while avoiding displacement of T4 and T, from thyroxin-binding globulin. Clin Chem 1988; 34: 17–23
  • Gupta M K, Salazar R, Schumacher O P. A solid phase radioimmunoassay for the measurement of free thyroxine. A new screening test for thyroid function? Am J Clin Pathol 1983; 79: 334–40
  • Rajan M GR, Samuel A M. A two-step radioimmunoassay for free triiodothyronine in serum. Clin Chem 1987; 33: 372–6
  • Reiners C, Becker W, Borner W. Erste Ergebnisse dcr Klinischen Priifung des neuen Zweischritt Radioimmunoassays FT4-RIAgnost. NucCompact 1987; 18: 205–8
  • Amino N, Nishi K, Nakatani K, Mizuta H, Ichihara K, Tanizawa O, Miyal K. Effect of albumin concentration on the assay of serum free thyroxin by equilibrium radioimmunoassay with labeled thyroxin analog (Amerlex® Free T4). Clin Chem 1983; 29: 321–5
  • Bayer M F. Free thyroxine results are affected by albumin concentration and nonthyroidal illness. Clin Chim Acta 1983; 130: 391–6
  • Liewendahl K, Tikanoja S, Helenius T, Valimaki M. Discrepancies between serum free triiodothyronine and free thyroxin as measured by equilibrium dialysis and analog radioimmunoassay in nonthyroidal illnesses. Clin Chem 1984; 30: 760–2
  • Nelson J C, Weiss R M. The effect of serum dilution on free thyroxine (T4) concentration in the low T4 syndrome of nonthyroidal illness. J Clin Endocrinol Metab 1985; 61: 239–46
  • Munro S L, Lim C-F, Hall J G, Barlow J W, Craik D J, Topliss D J, Stockigt J R. Drug competition for thyroxine binding to transthyretin (prealbumin): comparison with effects on thyroxine-binding globulin. J Clin Endocrinol Metab 1989; 68: 1141–7
  • Csako G, Zweig M H, Glickman J, Kestner J, Ruddel M. Direct and indirect techniques for free thyroxin compared in patients with nonthyroidal illness. I. Effect of free fatty acids. Clin Chem 1989; 35: 102–9
  • Mac Mahon W, Stallings J, Sgoutas D. A simple ultrafiltration method for determining unbound estradiol in serum. Clin Biochem 1983; 16: 240–3
  • Jerkunica I, Sophianopoulos J, Sgoutas D. Improved ultrafiltration method for determining unbound Cortisol in plasma. Clin Chem 1980; 26: 1734–7
  • Kurz H, Trunk H, Weitz B. Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentri-fugation, gel filtration. Arzneim-Forsch/Drug Res 1977; 27: 1373–80
  • Shannon N, Woolf P D. Determination of free thyroxin in serum by ultrafiltration: validation of a method and preliminary results. Clin Chem 1984; 30: 1770–3
  • Wang Y-S, Hershman J M, Pekary A E. Improved ultrafiltration method for simultaneous measurement of free thyroxin and free triiodothyronine in serum. Clin Chem 1985; 31: 517–22
  • Sophianopoulos J, Jerkunica I, Lee C N, Sgoutas D. An improved ultrafiltration method for free thyroxine and triiodothyronine in serum. Clin Chem 1980; 26: 159–62
  • Weeke J, Boyc N, Orskov H. Ultrafiltration method for direct radioimmunoassay measurement of free thyroxine and free tri-iodothyronine in serum. Scand J Clin Lab Invest 1986; 46: 381–9
  • Tikanoja S, Liewendahl K. Protein leakage in ultrafiltration devices. 8th European Congress of Clinical Chemistry, Milano. Biochimica Clinica 1989; 13(Suppl. 1/8)175, (Abstract)
  • Liewendahl K, Mähönen H, Tikanoja S, Helenius T, Turula M, Välimäki M. Performance of direct equilibrium dialysis and analogue-type free thyroid hormone assays, and an immunoradiometric TSH method in patients with thyroid dysfunction. Scand J Clin Lab Invest 1987; 47: 421–8
  • Pedersen K O. Simultaneous determination of the free thyroxine and triiodothyronine fractions in serum. Scand J Clin Lab Invest 1974; 34: 241–6
  • Faber J, Rogowski P, Kirkegaard C, Siersbsk-Nielsen K, Friis T. Serum free T4, T3, rT-,3,3′-diiodothyronine and 3′,5′-diiodothyronine measured by ultrafiltration. Acta Endocrinol 1984; 107: 357–65
  • Chopra I J, Huang T-S, Beredo A, Solomon D H, Chua Teco G N. Serum thyroid hormone binding inhibitor in nonthyroidal illnesses. Metabolism 1986; 35: 152–9
  • Oppenheimer J H, Surks M I. Determination of free thyroxine in human serum: a theoretical and experimental analysis. J Clin Endocrinol Metab 1964; 24: 785–93
  • Pettersson T M. Studies on thyroxine binding globulin and transthyretin (prealbumin) with special reference to their significance for free thyroxine concentration. Dissertation, Karolinska Institutet, Danderyd Hospital, Sweden 1989; 1–86

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