Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 46, 2011 - Issue 1
Submit an article Journal homepage
129
Views
11
CrossRef citations to date
0
Altmetric
Gastrointestinal Cancer

Lentiviral vector-mediated upregulation of let-7a inhibits gastric carcinoma cell growth in vitro and in vivo

Yimin Zhu Department of General Surgery, The Second Hospital of Jiaxing, Jiaxing, PR China
,
Zhengxiang Zhong Department of General Surgery, The Second Hospital of Jiaxing, Jiaxing, PR China
&
Zhiming Liu Department of General Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, PR ChinaCorrespondence[email protected]
Pages 53-59 | Received 10 Jan 2010, Accepted 19 Jul 2010, Published online: 01 Sep 2010

References

  • Ambros V. The functions of animal microRNAs, Nature 2004;431:350–5. PMID: 15372042.
  • Bartel DP, Chen CZ. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet 2004;5:396–400. PMID: 15143321.
  • Kloosterman WP, Plasterk RH. The diverse functions of microRNAs in animal development and disease. Dev Cell 2006;11:441–50. PMID: 17011485.
  • Zeng Y. Principles of micro-RNA production and maturation. Oncogene 2006;25:6156–62. PMID: 17028594.
  • Valencia-Sanchez MA, Liu J, Hannon GJ. Control of translation and mRNA degradation by miRNAs and siRNAs. Gene Dev 2006;20:515–24. PMID: 16510870.
  • Bentwich I, Avniel A, Karov Y. Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet 2005;37:766–70. PMID: 15965474.
  • Berezikov E, Van TG, Verheul M. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res 2006;16:1289–98. PMID: 16954537.
  • Didiano D, Hobert O. Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions. Nat Struct Mol Biol 2006;13:849–51. PMID: 16921378.
  • Zhu Y, Liu Z. Roles of onco-microRNAs in cancers. J Intern Oncol 2008;35(12):883–5.
  • Zhu Y, Zhong Z, Liu Z. Significance and relationship between let-7a and gastric mucosa cancerization. World J Gastroenterol 2010;16(26):3325–9. PMID: 20614490.
  • Zhang B, Metharom P, Jullie H. The significance of controlled conditions in lentiviral vector titration and in the use of multiplicity of infection (MOI) for prediction gene transfer events. Genet Vaccines Ther 2004;2:6. PMID: 15291957.
  • Bernard PS, Wittwer CT. Real-time PCR technology for cancer diagnostics. Clin Chem 2002;48:1178–85. PMID: 12142370.
  • Reinhart BJ, Slack FJ, Basson M. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000;403:901–6. PMID: 10706289.
  • Abrahante JE, Daul AL, Li M. The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell 2003;4:625–37. PMID: 12737799.
  • Lin SY, Johnson SM, Abraham M. The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev Cell 2003;4:639–50. PMID: 12737800.
  • Slack FJ, Basson M, Liu Z. The lin-41 RBCC gene acts in the C elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 2000;5:659–69. PMID: 10882102.
  • Vella MC, Choi EY, Lin SY. The C elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR. Genes Dev 2004;18:132–7. PMID: 14729570.
  • Dong Q, Meng P, Wang T, Qin W, Qin W, Wang F, MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2. PLoS One 2010;5:10137–47. PMID: 20418948.
  • Yu F, Yao H, Zhu P. Let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 2007;131:1109–23. PMID: 18083101.
  • Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007;16:1576–9. PMID: 17322030.
  • Akao Y, Nakagawa Y, Naoe T. Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol Pharm Bull 2006;29:903–6. PMID: 16651716.
  • Aurora E-K, Trang P, Wiggins JF. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 2008;7:759–64. PMID: 18344688.
  • Motoyama K, Inoue H, Nakamura Y, Uetake H, Sugihara K, Mori M. Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. Clin Cancer Res 2008;14:2334–40. PMID: 18413822.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.