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Peptic Ulcer

Investigation of ABCB1 1236 and 2677 SNPs in patients with peptic ulcer

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Pages 22-27 | Received 06 Sep 2011, Accepted 11 Oct 2011, Published online: 16 Nov 2011

References

  • Terao T, Hisanaga E, Sai Y, Tamai I, Tsuji A. Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier. J Pharm Pharmacol 1996;48:1083–9.
  • Mochida Y, Taguchi K, Taniguchi S, Tsuneyoshi M, Kuwano H, Tsuzuki T, The role of P-glycoprotein in intestinal tumourigenesis: disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice. Carcinogenesis 2003;24:1219–24.
  • Siegsmund M, Brinkmann U, Schaffeler E, Weirich G, Schwab M, Eichelbaum M, Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumours. J Am Soc Nephrol 2002;13:1847–54.
  • Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exp Ther 2001;297:1137–43.
  • Randolph GJ, Beaulieu S, Pope M, Sugawara I, Hoffman L, Steinman RM, A physiologic function for p-glycoprotein (MDR−1) during the migration of dendritic cells from skin via afferent lymphatic vessels. Proc Natl Acad Sci USA 1998;95:6924–9.
  • Smyth MJ, Krasovskis E, Sutton VR, Johnstone RW. The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumour cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci USA 1998;95:7024–9.
  • Johnstone RW, Cretney E, Smyth MJ. P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death. Blood 1999;93:1075–85.
  • Sparreboom A, Danesi R, Ando Y, Chan J, Figg WD. Pharmacogenomics of ABC transporters and its role in cancer chemotherapy. Drug Resist Updat 2003;6:71–84.
  • Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 1999;39:361–98.
  • Sakaeda T, Nakamura T, Okumura K. Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs. Pharmacogenomics 2003;4:397–410.
  • Tanigawara Y. Role of P-glycoprotein in drug disposition. Ther Drug Monit 2000;22:137–40.
  • Marzolini C, Paus E, Buclin T, Kim RB. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther 2004;75:13–33.
  • Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, A “silent” polymorphism in the MDR1 gene changes substrate specificity. Science 2007;315:525–8.
  • Sałagacka A, Bartczak M, Żebrowska M, Jażdżyk M, Balcerczak M, Janiuk R, C3435T polymorphism of the ABCB1 gene:impact on genetic susceptibility to peptic ulcers. Pharmacol Rep 2011;63:992–8.
  • Gervasini G, Carrillo JA, Garcia M, San Jose C, Cabanillas A, Benitez J. Adenosine triphosphate-binding cassette B1 (ABCB1) (Multidrug resistance 1) G2677T/A gene polymorphism is associated with high risk of lung cancer. Cancer 2006;107:2850–7.
  • Maleki M, Sayyah M, Kamgarpour F, Karimipoor M, Arab A, Rajabi A, Association between ABCB1-T1236C polymorphism and drug-resistant epilepsy in Iranian female patients. Iran Biomed J 2010;14:89–96.
  • Marsh SH, King CR, McLeod HL, Paul J, Gifford G, Brown R, ABCB1 2677G>T/A genotype and paclitaxel pharmacogenetics in ovarian cancer. Clin Cancer Res 2006;12:4127–9.
  • Jamroziak K, Balcerczak E, Całka K, Piaskowski S, Urbanska-Rys H, Salagacka A, Polymorphisms and haplotypes in the multidrug resistance 1 gene (MDR1/ABCB1) and risk of multiple myeloma. Leuk Res 2009;33:332–5.
  • Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001;69:169–74.
  • Panczyk M, Balcerczak E, Piaskowski S, Jamroziak K, Pasz-Walczak G, Mirowski M. ABCB1 gene polymorphisms and haplotype analysis in colorectal cancer. Int J Colorectal Dis 2009;24:895–905.
  • Fromm MF. The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans. Adv Drug Deliv Rev 2002;54:1295–310.
  • Brant SR, Panhuysen CIM, Nicolae D, Reddy DM, Bonen DK, Karaliukas R. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet 2003;73:1282–92.
  • Ho GT, Nimmo ER, Tenesa A, Fennell J, Drummond H, Mowat C, Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis. Gastroenterology 2005;128:288–96.
  • Ho GT, Moodie FM, Satsangi J. Multidrug resistance 1 gene (P-glycoprotein 170): an important determinant in gastrointestinal disease? Gut 2003;52:759–66.

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