NcoI TNF-β gene polymorphism and TNF expression are associated with an increased risk of developing Barrett's esophagus and esophageal adenocarcinoma

References

• Blot WJ, Devesa SS, Kneller RW, Fraumeni JF Jr. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. Jama 1991;265:1287–9.
   PubMed Web of Science ®Google Scholar
• Hamilton SR, Smith RR. The relationship between columnar epithelial dysplasia and invasive adenocarcinoma arising in Barrett's esophagus. Am J Clin Pathol 1987;87:301–12.
   PubMed Web of Science ®Google Scholar
• Lagergren J, Bergstrom R, Lindgren A, Nyren O. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 1999;340:825–31.
   PubMed Web of Science ®Google Scholar
• Izzo JG, Luthra R, Wu TT, Molecular mechanisms in Barrett's metaplasia and its progression. Semin Oncol 2007;34(2 Suppl 1):S2–6.
   Google Scholar
• Balkwill F, Coussens LM. Cancer: an inflammatory link. Nature 2004;431:405–6.
   PubMed Web of Science ®Google Scholar
• Dranoff G. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 2004;4:11–22.
   PubMed Web of Science ®Google Scholar
• Komori A, Yatsunami J, Suganuma M, Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation. Cancer Res 1993;53:1982–5.
   PubMed Web of Science ®Google Scholar
• Hamaguchi M, Fujiwara Y, Takashima T, Increased expression of cytokines and adhesion molecules in rat chronic esophagitis. Digestion 2003;68:189–97.
   PubMed Web of Science ®Google Scholar
• Schmitz H, Fromm M, Bentzel CJ, Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6. J Cell Sci 1999;112:137–46.
   PubMed Web of Science ®Google Scholar
• Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 1996;334:1717–25.
   PubMed Web of Science ®Google Scholar
• Bouma G, Crusius JB, Oudkerk Pool M, Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease. Scand J Immunol 1996;43:456–63.
   PubMed Web of Science ®Google Scholar
• Messer G, Spengler U, Jung MC, Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production. J Exp Med 1991;173:209–19.
   PubMed Web of Science ®Google Scholar
• Li C, Xia B, Yang Y, Li J, Xia HH. TNF gene polymorphisms and Helicobacter Pylori infection in gastric carcinogenesis in Chinese population. Am J Gastroenterol 2005;100:290–4.
   PubMedGoogle Scholar
• Lanas A, Garcia-Gonzalez MA, Santolaria S, TNF and LTA gene polymorphisms reveal different risk in gastric and duodenal ulcer patients. Genes Immun 2001;2:415–21.
   PubMed Web of Science ®Google Scholar
• Bronstein M, Pisante A, Yakir B, Darvasi A. Type 2 diabetes susceptibility loci in the Ashkenazi Jewish population. Hum Genet 2008;124:101–4.
   PubMed Web of Science ®Google Scholar
• Brown LM, Devesa SS. Epidemiologic trends in esophageal and gastric cancer in the United States. Surg Oncol Clin N Am 2002;11:235–56.
   PubMedGoogle Scholar
• van Blankenstein M, Looman CW, Johnston BJ, Caygill CP. Age and sex distribution of the prevalence of Barrett's esophagus found in a primary referral endoscopy center. Am J Gastroenterol 2005;100:568–76.
   PubMed Web of Science ®Google Scholar
• Hameeteman W, Tytgat GN, Houthoff HJ, van den Tweel JG. Barrett's esophagus: development of dysplasia and adenocarcinoma. Gastroenterology 1989;96:1249–56.
   PubMed Web of Science ®Google Scholar
• Haggitt RC. Barrett's esophagus, dysplasia, and adenocarcinoma. Hum Pathol 1994;25:982–93.
   PubMed Web of Science ®Google Scholar
• Chow WH, Finkle WD, McLaughlin JK, Frankl H, Ziel HK, Fraumeni JF Jr. The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia. Jama 1995;274:474–7.
   PubMed Web of Science ®Google Scholar
• Fitzgerald RC, Onwuegbusi BA, Bajaj-Elliott M, Saeed IT, Burnham WR, Farthing MJ. Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants. Gut 2002;50:451–9.
   PubMed Web of Science ®Google Scholar
• Moons LM, Kusters JG, Bultman E, Barrett's oesophagus is characterized by a predominantly humoral inflammatory response. J Pathol 207:269–76.
   PubMedGoogle Scholar
• Moons LM, Kusters JG, van Delft JH, A pro-inflammatory genotype predisposes to Barrett's esophagus. Carcinogenesis 2008;29:926–31.
   PubMedGoogle Scholar
• Tselepis C, Perry I, Dawson C, Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action. Oncogene 2002;21:6071–81.
   PubMed Web of Science ®Google Scholar
• Wilson AG, di Giovine FS, Duff GW. Genetics of tumour necrosis factor-alpha in autoimmune, infectious, and neoplastic diseases. J Inflamm 1995;45:1–12.
   PubMedGoogle Scholar
• Eksteen JA, Scott PA, Perry I, Jankowski JA. Inflammation promotes Barrett's metaplasia and cancer: a unique role for TNFalpha. Eur J Cancer Prev 2001;10:163–6.
   PubMedGoogle Scholar
• The International HapMap Project. Nature 2003;426:789–96.
   PubMed Web of Science ®Google Scholar
• Cameron AJ. Epidemiology of columnar-lined esophagus and adenocarcinoma. Gastroenterol Clin North Am 1997;26:487–94.
   PubMed Web of Science ®Google Scholar
• Wong A, Fitzgerald RC. Epidemiologic risk factors for Barrett's esophagus and associated adenocarcinoma. Clin Gastroenterol Hepatol 2005;3:1–10.
   PubMed Web of Science ®Google Scholar
• Hosch SB, Izbicki JR, Pichlmeier U, Expression and prognostic significance of immunoregulatory molecules in esophageal cancer. Int J Cancer 1997;74:582–7.
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57–70.
   PubMed Web of Science ®Google Scholar