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Esophagus

Effect of nitrite delivered in saliva on postprandial gastro-esophageal function

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Pages 387-396 | Received 23 Jun 2011, Accepted 01 Jan 2012, Published online: 20 Feb 2012

References

  • Botterweck AA, Schouten LJ, Volovics A, Dorant E, Van den Brandt PA. Trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European Countries. Int J Epidemiol 2000;29:645–54.
  • Mittal RK, Balaban DH. The esophagogastric junction. [Review] [54 Refs]. N Engl J Med 1997;336:924–32.
  • Richter J. Do we know the cause of Reflux disease?. [Review] [15 Refs]. Eur J Gastroenterol Hepatol 1999;11(Suppl 1):S3–9.
  • Cadiot G, Bruhat A, Rigaud D, Coste T, Vuagnat A, Benyedder Y, Multivariate analysis of pathophysiological factors in reflux oesophagitis. Gut 1997;40:167–74.
  • Tytgat GN, Janssens J, Reynolds JC, Wienbeck M. Update on the pathophysiology and management of gastro-oesophageal Reflux Disease: the role of prokinetic therapy. Eur J Gastroenterol Hepatol 1996;8:603–11.
  • Hirsch DP, Tiel-Van Buul MM, Tytgat GN, Boeckxstaens GE. Effect of L-NMMA on postprandial transient lower esophageal sphincter relaxations in healthy volunteers. Dig Dis Sci 2000;45:2069–75.
  • Eherer AJ, Schwetz I, Hammer HF, Petnehazy T, Scheidl SJ, Weber K, Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders. Gut 2002;50:758–64.
  • Simren M, Silny J, Holloway R, Tack J, Janssens J, Sifrim D. Relevance of ineffective oesophageal motility during oesophageal acid clearance. Gut 2003;52:784–90.
  • Rhee PL, Hyun JG, Lee JH, Kim YH, Son HJ, Kim JJ, The effect of sildenafil on lower esophageal sphincter and body motility in normal male adults. Am J Gastroenterol 2001;96:3251–7.
  • Sarnelli G, Sifrim D, Janssens J, Tack J. Influence of sildenafil on gastric sensorimotor function in humans. Am J Physiol Gastrointest Liver Physiol 2004;287:G988–92.
  • Tottrup A, Knudsen MA, Gregersen H. The role of the L-Arginine-Nitric oxide pathway in relaxation of the opossum lower oesophageal sphincter. Br J Pharmacol 1991;104:113–16.
  • Knudsen MA, Svane D, Tottrup A. Importance of the L-Arginine-Nitric oxide pathway in nanc nerve function of the opossum esophageal body. Dig Dis 1991;9:365–70.
  • Boulant J, Fioramonti J, Dapoigny M, Bommelaer G, Bueno L. Cholecystokinin and nitric oxide in transient lower esophageal sphincter relaxation to gastric distention in dogs.[See Comment]. Gastroenterology 1994;107:1059–66.
  • Kim H, Kim KH. Effects of a nitric oxide donor and nitric oxide synthase inhibitors on acid secretion of isolated rabbit gastric glands. Pharmacology 1996;53:331–9.
  • Stacher G, Lenglinger J, Eisler M, Hoffmann M, Goll A, Bergmann H, Esophageal acid exposure in upright and recumbent postures: roles of lower esophageal sphincter, esophageal contractile and transport function, hiatal hernia, age, sex, and body mass. Dig Dis Sci 2006;51:1896–903.
  • Stacher G, Schneider C, Steinringer H, Satzinger U, Weber U. Sublingual nitroglycerine: effects on contractile activity of the distal oesophagus and lower oesophageal sphincter in healthy men. Aliment Pharmacol Ther 1996;10:883–8.
  • Bos PM, Van den Brandt PA, Wedel M, Ockhuizen T. The reproducibility of the conversion of nitrate to nitrite in human saliva after a nitrate load. Food Chem Toxicol 1988;26:93–7.
  • Tannenbaum SR, Weisman M, Fett D. The effect of nitrate intake on nitrite formation in human saliva. Food Cosmetics Toxicol 1976;14:549–52.
  • Bartholomew B, Hill MJ. The pharmacology of dietary nitrate and the origin of urinary nitrate. Food Chem Toxicol 1984;22:789–95.
  • Iijima K, Henry E, Moriya A, Wirz A, Kelman AW, McColl KE. Dietary nitrate generates potentially mutagenic concentrations of nitric oxide at the gastroesophageal junction. [See Comment]. Gastroenterology 2002;122:1248–57.
  • Suzuki H, Iijima K, Moriya A, McElroy K, Scobie G, Fyfe V, Conditions for acid catalysed luminal nitrosation are maximal at the gastric cardia. Gut 2003;52:1095–101.
  • Iijima K, Fyfe V, McColl KE. Studies of nitric oxide generation from salivary nitrite in human gastric juice. Scand J Gastroenterol 2003;38:246–52.
  • O'Connor HJ, Schorah CJ, Habibzedah N, Axon AT, Cockel R. Vitamin C in the human stomach: relation to gastric pH, Gastroduodenal Disease, and possible sources. Gut 1989;30:436–42.
  • Bove M, Lundell L, Ny L, Casselbrant A, Fandriks L, Pettersson A, Effects of dietary nitrate on oesophageal motor function and gastro-oesophageal acid exposure in healthy volunteers and reflux patients. Digestion 2003;68:49–56.
  • Ghosh SK, Pandolfino JE, Zhang Q, Jarosz A, Shah N, Kahrilas PJ. Quantifying esophageal peristalsis with high-resolution manometry: a Study of 75 Asymptomatic Volunteers. Am J Physiol Gastrointest Liver Physiol 2006;290:G988–97.
  • Clarke AT, Wirz AA, Seenan JP, Manning JJ, Gillen D, McColl KE. Paradox of gastric cardia: it becomes more acidic following meals while the rest of stomach becomes less acidic. Gut 2009;58:904–9.
  • Meier-Augenstein W, Kemp HF, Preston T. A test meal suitable for measuring gastric emptying of solids by means of a [13C-1]-sodium acetate breath test. Proceedings of the Nutrition Society 60, 9A. 2001.
  • Sifrim D, Castell D, Dent J, Kahrilas PJ. Gastro-Oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux. [Review] [50 Refs]. Gut 2004;53:1024–31.
  • Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995;268(1 Pt 1):G128–33.
  • Viramontes BE, Kim DY, Camilleri M, Lee JS, Stephens D, Burton DD, Validation of a stable isotope gastric emptying test for normal, accelerated or delayed gastric emptying. Neurogastroenterol Motil 2001;13:567–74.
  • Johnsson F, Joelsson B. Reproducibility of ambulatory oesophageal pH monitoring. Gut 1988;29:886–9.
  • Manning JJ, Wirz AA, McColl KE. Nitrogenous chemicals generated from acidification of saliva influence transient lower oesophageal sphincter relaxations. Scand J Gastroenterol 2007;42:1413–21.
  • Clarke AT, Wirz AA, Manning JJ, Ballantyne SA, Alcorn DJ, McColl KE. Severe Reflux disease is associated with an enlarged unbuffered proximal gastric acid pocket. Gut 2008;57:292–7.
  • Kahrilas PJ, Lin S, Chen J, Manka M. The effect of hiatus hernia on gastro-oesophageal junction pressure. [See Comment]. Gut 1999;44:476–82.
  • Zerbib F, Bruley des V, Scarpignato C, Leray V, D'Amato M, Roze C, Endogenous cholecystokinin in postprandial lower esophageal sphincter function and fundic tone in humans. Am J Physiol 1998;275(6 Pt 1):G1266–73.
  • Trudgill NJ, Hussain FN, Moustafa M, Ajjan R, D'Amato M, Riley SA. The effect of cholecystokinin antagonism on postprandial lower oesophageal sphincter function in asymptomatic volunteers and patients with Reflux disease. Aliment Pharmacol Ther 2001;15:1357–64.
  • Mittal RK, Fisher M, McCallum RW, Rochester DF, Dent J, Sluss J. Human lower esophageal sphincter pressure response to increased intra-abdominal pressure. Am J Physiol 1990;258(4 Pt 1):G624–30.
  • Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension 2008;51:784–90.

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