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Scandinavian Journal of Gastroenterology Volume 47, 2012 - Issue 5
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Liver and Bilary Disease

The expression kinetics of CD137 in chronic hepatitis C patients treated with pegylated-interferon and ribavirin

Sang Jin LeeDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
,
Jung Woo ShinDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea;Biomedical Research Center, Ulsan University Hospital, Ulsan, KoreaCorrespondence[email protected]
,
Bo Ryung ParkBiomedical Research Center, Ulsan University Hospital, Ulsan, Korea
,
Chang Jae KimBiomedical Research Center, Ulsan University Hospital, Ulsan, Korea
,
Seok Won JungDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
,
Byunggyu KimDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
,
In Du JeongDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
,
Sung-Jo BangDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
&
Neung Hwa ParkDepartment of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea;Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea
 show all
Pages 601-606 | Received 07 Dec 2011, Accepted 15 Feb 2012, Published online: 15 Mar 2012

References

  • Pollok KE, Kim YJ, Zhou Z, Hurtado J, Kim KK, Pickard RT, Inducible T cell antigen 4-1BB analysis of expression and function. J Immunol 1993;150:771–81.
  • Croft M. Co-stimulatory members of the TNFR family: keys to effective T-cell immunity. Nat Rev Immunol 2003;3:609–20.
  • Watts TH. TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 2005;25:23–68.
  • Armstrong GL, Wasley A, Simard EP, McQuillan GM, Kuhnert WL, Alter MJ. The prevalence of hepatitis C virus infection in the United States, 1999 through 2002. Ann Intern Med 2006;144:705–14.
  • El-Serag HB, Davila JA, Petersen NJ, McGlynn KA. The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update. Ann Intern Med 2003;139:817–23.
  • Tilg H. New insights into the mechanisms of interferon α: an immunoregulatory and anti-inflammatory cytokine. Gastroenterology 1997;112:1017–21.
  • Ji X, Cheung R, Cooper S, Li Q, Greenberg HB, He XS. Interferon alfa regulated gene expression in patients initiating interferon treatment for chronic hepatitis C. Hepatology 2003;37:610–21.
  • Helbig KJ, Lau DT, Semendric L, Harley HA, Beard MR. Analysis of ISG expression in chronic hepatitis C identifies viperin as a potential antiviral effector. Hepatology 2005;42:702–10.
  • Cheng PN, Wei YL, Chang TT, Chen JS, Young KC. Therapy with interferon-alpha and ribavirin for chronic hepatitis C virus infection upregulates membrane HLA-ABC, CD86, and CD28 on peripheral blood mononuclear cells. J Med Virol 2008;80:989–96.
  • Kanto T, Hayashi N, Takehara T, Tatsumi T, Kuzushita N, Ito A, Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J Immunol 1999;162:5584–91.
  • Maerten P, Geboes K, De Hertogh G, Shen C, Cadot P, Bullens DM, Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease. Clin Immunol 2004;112:239–46.
  • Cramp ME, Rossol S, Chokshi S, Carucci P, Williams R, Naoumov NV. Hepatitis C virus-specific T cell reactivity during interferon and ribavirin treatment in chronic hepatitis C. Gastroenterology 2000;118:346–55.
  • Kamal SM, Fehr J, Roesler B, Peters T, Rasenack JW. Peginterferon alone or with ribavirin enhances HCV-specific CD4 T-helper 1 responses in patients with chronic hepatitis C. Gastroenterology 2002;123:1070–83.
  • Kamal SM, Ismail A, Graham CS, He Q, Rasenack JW, Peters T, Pegylated interferon alpha therapy in acute hepatitis C: relation to hepatitis C virus-specific T cell response kinetics. Hepatology 2004;39:1721–31.
  • Tatsumi T, Takehara T, Miyagi T, Nakazuru S, Mita E, Kanto T, Hepatitis C virus-specific CD8+ T cell frequencies are associated with the responses of pegylated interferon-α and ribavirin combination therapy in patients with chronic hepatitis C virus infection. Hepatol Res 2011;41:30–8.
  • Arends JE, Claassen MA, van den Berg CH, Nanlohy NM, van Erpecum KJ, Baak BC, T-cell responses at baseline and during therapy with peginterferon-alpha and ribavirin are not associated with outcome in chronic hepatitis C infected patients. Antiviral Res 2010;87:353–60.

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