Effects of Mesalazine Substitution on Salicylazosulfapyridine-Induced Seminal Abnormalities in Men with Ulcerative Colitis

References

• Levi A J, Fisher A M, Hughes L, Hendry W F. Male infertility due to sulphasalazine. Lancet 1979; 2: 276–278
   PubMed Web of Science ®Google Scholar
• Toth A. Reversible toxic effect of salicylazo-sulphapyridine on semen quality. Fertil Steril 1979; 31: 538–540
   PubMed Web of Science ®Google Scholar
• Birnie G G, McLeod T IF, Watkinson G. Incidence of sulphasalazine-induced male infertility. Gut 1981; 22: 452–455
   PubMed Web of Science ®Google Scholar
• Cann P A, Holdsworth C D. Reversal of male infertility on changing treatment from sulphasalazine to 5-aminosalicylic acid. Lancet 1984; 1: 1119
   PubMedGoogle Scholar
• Schaffer J L, Kershaw A, Berrisford M H. Sul-phasalazine-induced infertility reversed on transfer to 5-aminosalisylic acid. Lancet 1984; 1: 1240
   Google Scholar
• Riley S A, Lecarpentier J, Mani V, Goodman M J, Mandal B K, Turnberg L A. Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalazine substitution. Gut 1987; 28: 1008–1012
   PubMed Web of Science ®Google Scholar
• Chatzinoff M, Guarion J M, Corson S L, Batzer F R, Friedman L S. Sulphasalazine-induced abormal sperm penetration essay reversed on changing to 5-aminosalicylic acid enemas. Dig Dis Sci 1988; 33: 108–110
   PubMedGoogle Scholar
• O'Morain C, Smethurst P, Dore C J, Levi A J. Reversible male infertility due to sulphasalazine: studies in man and rat. Gut 1984; 25: 1078–1084
   PubMed Web of Science ®Google Scholar
• Wenner W J, Keating M A, Piccoli D A, Watkins J B, Levin R M. The effect of prepubertal sulphasalazine on sperm development and body weight in the rat. Gastroenterology 1988; 94(5)A 493, Pt II
   Google Scholar
• Hansen S H. Assay of 5-aminosalicylate and its ace-tylated metabolite in biological fluids by high-performance liquid chromatography on dynamically modified silica. J Chromatogr 1981; 226: 504–509
   PubMed Web of Science ®Google Scholar
• Bondesen S, Tage-Hansen U, Jacobsen D, Hansen S H, Rasmussen S N, Hvidberg E F. 5-Aminosalicylic acid in patients with an ileo-rectal anastomosis. A comparison of the fate of sulfasalazine and pentasa. Eur J Clin Pharmacol 1986; 31: 23–26
   PubMedGoogle Scholar
• World Health Organisation. Laboratory manual for the examination of human semen and semen-cervical mucus interaction, M A Belsey, et al. Press Concern, Singapore 1980
   Google Scholar
• World Health Organisation. WHO laboratory manual for the examination of human semen and semen-cervical mucus interaction, R J Aitken, et al. Cambridge University Press, Cambridge 1987
   Google Scholar
• Zelissen P MJ, Van Hattum J, Poen H, Scholten P, Gerritse R, Te Velde E R. Influence of sala-zosulphapyridine and 5-aminosalicylic acid on seminal qualities and male sex hormones. Scand J Gastroenterol 1988; 23: 1100–1104
   PubMed Web of Science ®Google Scholar
• Karp L E, Williamson R A, Moore D E, Shy K K, Plymate S R, Smith W D. Sperm penetration assay: Useful test in evaluation of male fertility. Obstet Gynecol 1981; 57: 620–623
   PubMed Web of Science ®Google Scholar
• Hargreave T B, McGovan B, Harvey J, McParland M, Elton Ra. Is a male infertility clinic of any use?. Br J Urol 1986; 58: 188–193
   PubMedGoogle Scholar
• Zaini A, Jennings M G, Baker H WG. Are conventional sperm morphology and motility assessments of predictive value in subfertile men?. Int J Androl 1985; 8: 427–435
   PubMedGoogle Scholar
• Rasmussen S N, Bondesen S, Hvidberg E F, et al. 5-aminosalicylic acid in a slow-release preparation: bioavailability, plasma level, and excretion in humans. Gastroenterology 1982; 83: 1062–72
   PubMed Web of Science ®Google Scholar
• Drife J O. The effects of drugs on sperm. Drugs 1987; 33: 610–622
   PubMed Web of Science ®Google Scholar
• Meese C O, Fischer C, Klotz V. Is N-acetylation of 5-aminosalicylic acid reversible in man?. Br J Pharmacol 1984; 18: 612–615
   Google Scholar
• Pieniaszek H JJ, Bates T R. Capacity limited gut wall metabolism of 5-aminosalicylic acid, a therapeutically active metabolite of sulphasalazine, in rats. J Pharm Sci 1979; 68: 1323–1325
   PubMed Web of Science ®Google Scholar
• Christensen L A, Rasmussen S N, Hansen S H, Bondesen S, Hvidberg E F. Salazosulphapyridine and metabolites in fetal and maternal body fluids with special reference to 5-aminosalicylic acid. Acta Obstet Gynecol Scand 1987; 66: 433–435
   PubMed Web of Science ®Google Scholar
• Das K M, Eastwood M A, McManus J PA, Sircus W. The metabolism of salicylazosulphapyridine in ulcerative colitis. The relationship between metabolites and the response to treatment in patients. Gut 1973; 14: 631–641
   PubMedGoogle Scholar