11
Views
6
CrossRef citations to date
0
Altmetric
Original Article

Effects of the Muscarinic Receptor Agonist Carbachol and/or Antagonist Pirenzepine on Gastric Mucus Secretion in Rats

, , , &
Pages 647-651 | Received 10 Aug 1992, Accepted 01 Feb 1993, Published online: 08 Jul 2009

References

  • Kojima Y, Ishihara K, Ohara S, Saigenji K, Hotta K. Effects of the M1 muscarinic receptor antagonist pirenzepine on gastric mucus glycoprotein in rats with or without ethanol-induced gastric damage. Scand J Gastroenterol 1992; 27: 764–8
  • Azuumi Y, Ohara S, Ishihara K, Okabe H, Hotta K. Correlation of quantitative changes of gastric musosal glycoproteins with aspirin-induced gastric damage in rats. Gut 1980; 21: 533–7
  • Ohara S, Ishihara K, Hotta K. Comparative study on mucus glycoproteins in rat stomach and duodenum. Comp Biochem Physiol 1985; 83B: 325–9
  • Ishihara K, Ohara S, Azuumi Y, Goso K, Hotta K. Changes of gastric mucus glycoproteins with aspirin administration in rats. Digestion 1984; 29: 98–102
  • Komuro Y, Ishihara K, Ohara S, Saigenji K, Hotta K. A new method of separation and quantitation of mucus glycoprotein in rat gastric mucus gel layer and its application to mucus secretion induced by 16,16-dimethyl PGE2. Gastroenterol Jpn 1991; 26: 582–7
  • Komuro Y, Ishihara K, Ishii K, et al. A separation method for quantifying mucus glycoprotein localized in the different layer of rat gastric mucosa. Gastroenterol Jpn 1992; 27: 466–72
  • Gerard A, Lev R, Glass G BJ. Histochemical study of the mucosubstances in the canine stomach. II. The effects of histamine, gastrin, urecholine, and food. Lab Invest 1968; 19: 29–39
  • Ishihara H, Shimura S, Satoh M, et al. Muscarinic receptor subtypes in feline tracheal submucosal gland secretion. Am J Physiol 1992; 262: L223–8
  • Phillips T E. Both crypt and villus intestinal goblet cells secrete mucin in response to cholinergic stimulation. Am J Physiol 1992; 262: G327–31
  • Hollander F. The physiology and the chemistry of the secretion of gastric mucus. Gastroenterology 1962; 43: 304–9
  • Vague M, Perret G. Interaction of secretion and carba-minolcholine on gastric secretion in cats. Digestion 1974; 11: 215–25
  • Seidler U, Sewing K FR. Ca2+-dependent and -independent secretagogue action on gastric mucus secretion in rabbit mucosal explants. Am J Physiol 1989; 256: G739–46
  • Ota H, Katsuyama T, Ishii K, Nakayama J, Shiozawa T, Tsuka-Hara Y. A dual staining method for identifying mucins of different gastric epithelial mucous cells. Histochem J 1991; 23: 22–8
  • Ota H, Katsuyama T. Alternating laminated array of two types of mucins in the human gastric surface mucous gel layer. Histochem J 1992; 24: 86–92
  • Kajimura K, Haga T, Ichiyama A, Kaneko E, Honda N. Car-bachol-induced potentiation and inhibition of acid secretion by guinea pig gastric gland. Eur J Pharmacol 1990; 178: 59–69
  • Hammer R, Berrie C P, Birdsall M JM, Burgen A SV, Hulme E G. Pirenzepine distinguishes between different subclasses of muscarinic receptors. Nature 1980; 283: 90–2
  • Heathcote B V, Parry M. Pirenzepine selectively inhibits gastric acid secretion: a comparative pharmacological study between pirenzepine and seven other antiacetylcholine drugs. Scand J Gastroenterol 1980; 15: 15–24, Suppl 66
  • Komuro Y, Ishihara K, Ohara S, Saigenji K, Hotta K. Effects of tetragastrin on mucus glycoprotein in rat gastric mucosal protection. Gastroenterol Jpn 1992; 27: 597–603

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.