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Xenobiotica
the fate of foreign compounds in biological systems
Volume 17, 1987 - Issue 8
73
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Original Article

Identification in in vivo acetylation pathway for N-dealkylated metabolites of doxylamine in humans

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Pages 993-999 | Received 01 Oct 1986, Published online: 30 Sep 2009

References

  • Dreyfuss J., Mischiler T. W., Neiss E. S., Shouw J. M., Schreiber E. C. Metabolism of procainamide in rhesus monkey and man. Clinical Pharmacology and Therapeutics 1972; 13: 366–371
  • Ganes D. A., Hindmarsh K. W., Midha K. K. Doxylamine metabolism in rat and monkey. Xenobiotica 1986; 16: 781–794
  • Gielsdorf V., Schubert K. Metabolism of doxylamine: isolation, identification and synthesis of some metabolites. Journal of Clinical Chemistry and Clinical Biochemistry 1981; 19: 485–490
  • Holder C. L., Korfmacher W. A., Slikker W., Jr., Thompson J. H. C., Gosnell A. B. Mass spectral characterization of doxylamine and its rhesus monkey urinary metabolites. Biomedical Mass Spectrometry 1985; 12: 151–158
  • Kolata G. B. How Safe is Benedictinr`. Science 1980; 210: 518–519
  • Mitchell A. A., Rosenberg L., Shapiro S., Sone D. Birth defects related to benedectin use in pregnancy. Journal of the American Medical Association 1981; 245: 2311–2314

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