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Xenobiotica
the fate of foreign compounds in biological systems
Volume 21, 1991 - Issue 2
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Original Article

Comparative enantioselectivity in the sulphoxidation of albendazole in man, dogs and rats

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Pages 217-221 | Received 14 Mar 1990, Accepted 20 Jul 1990, Published online: 27 Aug 2009

References

  • Ariens E. J. Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology. European Journal of Pharmacology 1984; 26: 663–668
  • Auret B. J., Boyd D. R., Henbest H. B. Stereoselectivity in the oxidation of sulphoxides to sulphones in the presence of Aspergillus niger. Journal of the Chemical Society (C) 1968; 2374–2376
  • Campbell D. B. Stereoselectivity in clinical pharmacokinetics and drug development. European Journal of Drug Metabolism and Pharmacokinetics 1990; 15: 109–125
  • Delatour P., Garnier F., Benoit E., Longin C. A correlation of toxicity of albendazole and oxfendazole with their free metabolites and bound residues. Journal of Veterinary Pharmacology and Therapeutics 1984; 7: 139–145
  • Delatour P., Benoit E., Caude M., Tambute A. Species differences in the generation of the chiral sulfoxide metabolite of albendazole in sheep and rats. Chirality 1990a; 2: 156–160
  • Delatour P., Benoit E., Garnier F., Besse S. Chirality of the sulfoxide metabolites of fenbendazole and albendazole in sheep. Journal of Veterinary Pharmacology and Therapeutics 1990b; 361–366
  • Fargetton X., Galtier P., Delatour P. Sulfoxidation of albendazole by a cytochrome P450-independent monooxygenase from rat liver microsomes. Veterinary Research Communications 1986; 10: 317–324
  • Gyurik R. J., Chow A. W., Zaber B., Bruner E. L., Miller J. A., Villani A. J., Petka L. A., Parish R. C. Metabolism of albendazole in cattle, sheep, rats and mice. Drug Metabolism and Disposition 1981; 9: 503–508
  • Jamali F., Mehvar R., Pasutto F. M. Enantioselective aspects of drug action and disposition: therapeutic pitfalls. Journal of Pharmaceutical Sciences 1989; 78: 695–715
  • Lienne M., Caude M., Rosset R., Tambute A. Direct resolution of anthelmintic drug enantiomers on chiral-AGP protein-bonded chiral stationary phase. Journal of Chromatography 1989a; 472: 265–270
  • Lienne M., Caude M., Rosset R., Tambute A., Delatour P. Direct separation of albendazole sulfoxide enantiomers by liquid chromatography on a chiral column deriving from (S)-N-(3,5-dinitrobenzoyl) tyrosine. Chirality 1989b; 1: 142–153
  • Light D. R., Waxman D. J., Walsh C. Studies on the chirality of sulfoxidation catalyzed by bacterial flavoenzyme cyclohexanone monooxygenase and hog liver FAD containing monooxygenase. Biochemistry 1982; 21: 2490–2498
  • Marriner S. E., Morris D. L., Dickson B., Bogan J. A. Pharmacokinetics of albendazole in man. European Journal of Pharmacology 1986; 30: 705–708
  • Penicaut B., Maugien P. H., Maisonneuve M., Rossignol J. F. Pharmacocinétique et métabolisme urinaire de I'albendazole chez I'homme. Bulletin de la Société de Pathologic Exotique 1983; 76: 698–708
  • Souhaili-el-Amri H., Mothe O., Masson C., Batt A. M., Delatour P., Siest G. Albendazole sulfonation by rat liver cytochrome P-450 c. Journal of Pharmacology and Experimental Therapeutics 1988a; 246: 758–764
  • Souhaili-el-Amri H., Fargetton X., Benoit E., Totis M., Batt A. M. Inducing effect of albendazole on rat drug-metabolizing enzymes and metabolite pharmacokinetics. Toxicology and Applied Pharmacology 1988b; 92: 141–149
  • Testa B. Chiral aspects of drug metabolism. Trends in Pharmacological Sciences 1986; 7: 60–64
  • Waxman D. J., Light D. R., Walsh C. Chiral sulfoxidations catalyzed by rat liver cytochromes P-450. Biochemistry 1982; 21: 2499–2507
  • Ziegler D. H. S-oxygenases, I: Chemistry and biochemistry. Sulphur-containing Drugs and Related Organic Compounds, A. Damani. Ellis Horwood, ChichesterUK 1989; Vol. 2: 53–66, Part A

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