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Journal of Obstetrics and Gynaecology Volume 31, 2011 - Issue 1
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Gynaecology Case Reports

Metastatic placental site trophoblastic tumour successfully treated with hysterectomy and EMA/CO chemotherapy

Y. NagaiDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
,
A. WakayamaDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
,
S. SuzukiDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
,
K. AsatoDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
,
M. HirakawaDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
,
W. KudakaDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
,
M. InamineDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, Japan
&
Y. AokiDepartment of Obstetrics and Gynecology, Graduate School of Medical Science, University of the Ryukyus, Okinawa, JapanCorrespondence[email protected]
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Pages 99-101 | Published online: 31 Jan 2011

References

  • BaergenRN, RutgersJL, YoungRH et al. 2006. Placental site trophoblastic tumor: a study of 55 cases and review of the literature emphasizing factors of prognostic significance. Gynecologic Oncology 100:511–520.
  • BehtashN, Karimi ZarchiM. 2008. Placental site trophoblastic tumor. Journal of Cancer Research and Clinical Oncology 134:1–6.
  • ChangYL, ChangTC, HsuehS et al. 1999. Prognostic factors and treatment for placental site trophoblastic tumor. Report of 3 cases and analysis of 88 cases. Gynecologic Oncology 73:216–222.
  • FeltmateCM, GenestDR, WiseL et al. 2001. Placental site trophoblastic tumor: A 17-year experience at the New England Trophoblastic Disease Center. Gynecologic Oncology 82:415–419.
  • HassadiaA, GillespieA, TidyJ et al. 2005. Placental site trophoblastic tumour: clinical features and management. Gynecologic Oncology 99:603–607.
  • KurmanRJ, YoungRH, NorrisHJ et al. 1984. Immunocytochemical localization of placental lactogen and chorionic gonadotropin in the normal placenta and trophoblastic tumors, with emphasis on intermediate trophoblast and the placental site trophoblastic tumor. International Journal of Gynecological Pathology 3:101–121.
  • NagaiY, KamoiS, MatsuokaT et al. 2007. Impact of p53 immunostaining in predicting advanced or recurrent placental site trophoblastic tumors: a study of 12 cases. Gynecologic Oncology 106:446–452.
  • NewlandsES, MulhollandPJ, HoldenL et al. 2000. Etoposide and cisplatin/etoposide, methotrexate, and actinomycin D (EMA) chemotherapy for patients with high-risk gestational trophoblastic tumors refractory to EMA/cyclophosphamide and vincristine chemotherapy and patients presenting with metastatic placental site trophoblastic tumors. Journal of Clinical Oncology 18:854–859.
  • PapadopoulosAJ, FoskettM, SecklMJ et al. 2002. Twenty-five years' clinical experience with placental site trophoblastic tumors. Journal of Reproductive Medicine 47:460–464.
  • SchmidP, NagaiY, AgarwalR et al. 2009. Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study. Lancet 374:48–55.
  • SwisherE, DrescherCW. 1998. Metastatic placental site trophoblastic tumor: long-term remission in a patient treated with EMA/CO chemotherapy. Gynecologic Oncology 68:62–65.

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