Plasminogen activator inhibitor-1, factor V, factor II and methylenetetrahydrofolate reductase polymorphisms in women with recurrent miscarriage

References

• Allison JL, Shust DJ. 2009. Recurrent first trimester pregnancy loss: revised definitions and novel causes. Current Opinion in Endocrinology, Diabetes and Obesity 16:446–450.
   PubMed Web of Science ®Google Scholar
• Altintas A, Pasa S, Akdeniz N, Cil T, Yurt M, Ayyildiz O et al. 2007. Factor V Leiden and G20210A prothrombin mutations in patients with recurrent pregnancy loss. Data from the southeast of Turkey. Annals of Hematology 86:727–731.
   PubMed Web of Science ®Google Scholar
• Altomare I, Adler A, Aledort LM. 2007. The 5,10 methylenetetrahydrofolate reductase C677T mutation and the risk of fetal loss: a case series and review of the literature. Thrombosis Journal 5:17.
   PubMedGoogle Scholar
• Baek KH, Lee EJ, Kim YS. 2007. Recurrent pregnancy loss: the key potential mechanisms. Trends in Molecular Medicine 13:257–267.
   Web of Science ®Google Scholar
• Biswas A, Choudhry P, Mittal A, Meena A, Ranjan R, Choudhry VP et al. 2008. Recurrent abortions in Asian Indians: no role of factor V Leiden Hong Kong/Cambridge mutation and MTHFR polymorphism. Clinical and Applied Thrombosis/Hemostasis 14:102–104.
   PubMed Web of Science ®Google Scholar
• Christiansen OB, Nybo Andersen AM, Bosh E, Daya S, Delves PJ, Hviid TV et al. 2005. Evidence-based investigations and treatments of recurrent pregnancy loss. Fertility and Sterility 83:821–839.
   PubMed Web of Science ®Google Scholar
• Christiansen OB, Steffenson R, Nielsen H, Varming K. 2008. Multifactorial etiology of recurrent miscarriage and its scientific and clinical implications. Gynecologic and Obstetric Investigation 66:257–267.
   PubMed Web of Science ®Google Scholar
• Coulam CB, Jeyendran RS, Fishel LA, Roussev R. 2006. Multiple thrombophilic gene mutations rather than specific gene mutations are risk factors for recurrent miscarriage. American Journal of Reproductive Immunology 55:360–368.
   PubMed Web of Science ®Google Scholar
• Coulam CB, Wallis D, Weinstein J, DasGupta DS, Jeyendran RS. 2008. Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis. American Journal of Reproductive Immunology 60:426–431.
   PubMed Web of Science ®Google Scholar
• Di Micco P, D'Uva M, Strina I, De Placido G, Di Fiore R, Quaranta S et al. 2007. Recurrent pregnancy loss and thrombophilia. Clinical Laboratory 553:309–314.
   Google Scholar
• D’Uva M, Di Micco P, Strina I, Ranieri A, Alviggi C, Mollo A et al. 2008. Etiology of hypercoagulable state in women with recurrent fetal loss without other causes of miscarriage from Southern Italy: new clinical target for antithrombotic therapy. Biologics 2:897–902.
   PubMedGoogle Scholar
• Emmerich J, Rosendaal FR, Cattaneo M, Margaglione M, De Stefano V, Cumming T et al. 2001. Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism pooled analysis of 8 case–control studies including 2310 cases and 3204 controls. Study Group for Pooled-Analysis in Venous Thromboembolism. Thrombosis and Haemostasis 86:809–816.
   PubMed Web of Science ®Google Scholar
• Glueck CJ, Gogenini S, Munjal J, Tracy T, Pranikoff J, Wang P. 2008. Factor V Leiden mutation: a treatable etiology for sporadic and recurrent pregnancy loss. Fertility and Sterility 89:410–416.
   PubMed Web of Science ®Google Scholar
• Goodman CS, Coulam CB, Jeyendran RS, Acosta VA, Roussev R. 2006. Which thrombophilic gene mutations are risk factors for recurrent pregnancy loss?American Journal of Reproductive Immunology 56:230–236.
   PubMed Web of Science ®Google Scholar
• Goodmann C, Hur J, Goodman CS, Jeyendran RS, Coulam C. 2009. Are polymorphisms in the ACE and PAI-1 associated with recurrent spontaneous miscarriages?American Journal of Reproductive Immunology 62:365–370.
   PubMed Web of Science ®Google Scholar
• Govindaiah V, Naushad SM, Prabhakara K, Krishna PC, Radha Rama Devi A. 2009. Association of parental hyperhomocysteinemia and C677T Methylene tetrahydrofolate reductase (MTHFR) polymorphism with recurrent pregnancy loss. Clinical Biochemistry 42:380–386.
   PubMed Web of Science ®Google Scholar
• Grandone E, Colaiazzo D, Tiscia G, Vergura P, Cappucci F, Greco L et al. 2011. Impact of common thrombophilias and Jak2 V617F on pregnancy outcomes in unselected Italian women. Journal of Thrombosis and Haemostasis 9:496–501.
   PubMed Web of Science ®Google Scholar
• Gris JC, Schved JF, Neveu S, Mares P, Aguilar-Martinez P, Dupaigne D. 1990. Impaired fibrinolytic capacity and early recurrent spontaneous abortion. British Medical Journal 300:1500.
   PubMedGoogle Scholar
• Gris JC, Neveu S, Mares P, Biron C, Hedon B, Scheved JF. 1993. Plasmafibrinolytic activators and their inhibitors in women suffering from early recurrent abortion of unknown etiology. Journal of Laboratory and Clinical Medicine 22:606–615.
   Google Scholar
• Gumpel C, Fornasiero L, Suarez S, Santillan G, Colabianchi C. 2009. PAI-1 45/5G polymorphism detection and obstetric complications. Thrombosis Research 123:S148.
   Web of Science ®Google Scholar
• Ivanov PD, Komsa-Penkova RS, Konova EI, Kovacheva KS, Simeonova MN, Popov JD. 2009. Association of inherited thrombophilia with embryonic and postembryonic recurrent pregnancy loss. Blood Coagulation and Fibrinolysis 20:134–140.
   PubMed Web of Science ®Google Scholar
• Jaslow CR, Carney JL, Kutteh WH. 2009. Diagnostic factors identified in 1020 women with two versus three or more recurrent pregnancy losses. Fertility and Sterility 93:1234–1243.
   PubMed Web of Science ®Google Scholar
• Jivrai S, Rai R, Underwood J, Regan L. 2006. Genetic thrombophilic mutations among couples with recurrent miscarriage. Human Reproduction 21:1161–1165.
   PubMed Web of Science ®Google Scholar
• Jivraj S, Makris M, Saravelos S, Li TC. 2009. Pregnancy outcome in women with factor V Leiden and recurrent miscarriage. British Journal of Obstetrics and Gynaecology 116:995–998.
   Google Scholar
• Krabbendam I, Franx A, Bots ML, Fijnheer R, Bruinse HW. 2005. Thrombophilias and recurrent pregnancy loss: a critical appraisal of the literature. European Journal of Obstetrics, Gynecology, and Reproductive Biology 118:143–153.
   PubMed Web of Science ®Google Scholar
• Kwak-Kim J, Yang KM, Gilman-Sachs A. 2009. Recurrent pregnancy loss: a disease of inflammation and coagulation. Journal of Obstetrics and Gynaecology Research 35:609–622.
   PubMed Web of Science ®Google Scholar
• Lala PK, Graham CH. 1990. Mechanisms of trophoblast invasiveness and their control: the role of proteases and protease inhibitors. Cancer and Metastasis Reviews 9:369–379.
   PubMed Web of Science ®Google Scholar
• Lijfering WM, Middeldorp S, Veeger NJ, Hamulyák K, Prins MH, Büller HR et al. 2010. Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A. Circulation 121:1706–1712.
   PubMed Web of Science ®Google Scholar
• Lindhoff-Last E, Luxembourg B. 2008. Evidence-based indications for thrombophilia screening. VASA. Zeitschrift für Gefässkrankheiten 37:19–30.
   PubMedGoogle Scholar
• Lopez-Alemany R, Redondo JM, Nagamine Y, Munoz-Canoves P. 2003. Plasminogen activator inhibitor type-1 inhibits insulin signalling by competing with alphabeta3 integrin for vitronectin binding. European Journal of Biochemistry 270:814–821.
   PubMedGoogle Scholar
• Lund M, Nielsen HS, Hviid TV, Steffensen R, Nyboe Andersen A, Christiansen OB. 2010. Hereditary thrombophilia and recurrent pregnancy loss: a retrospective cohort study of pregnancy outcome and obstetric complications. Human Reproduction 25:2978–2984.
   PubMed Web of Science ®Google Scholar
• Masini S, Ticconi C, Gravina P, Tomassini M, Pietropolli A, Forte V et al. 2009. Thrombin-activatable fibrinolysis inhibitor polymorphisms and recurrent pregnancy loss. Fertility and Sterility 92:694–702.
   PubMed Web of Science ®Google Scholar
• Meinardi JR, Middeldorp S, de Kam PJ, Koopman MM, van Pampus EC, Hamulyák K et al. 2001. Risk of venous thromboembolism in carriers of factor V Leiden with a concomitant inherited thrombophilic defect: a retrospective analysis. Blood Coagulation and Fibrinolysis 12:713–720.
   PubMed Web of Science ®Google Scholar
• Morales-Machín A, Borjas-Fajardo L, Quintero JM, Zabala W, Alvarez F, Delgado W et al. 2009. C677T polymorphism of the methylenetetrahydrofolate reductase gene as risk factor in women with recurrent abortion. Investigacion Clinica 50:327–333.
   PubMed Web of Science ®Google Scholar
• Pasquier E, Bohec C, Mottier D, Jaffuel S, Mercier B, Férec C et al. 2009. Inherited thrombophilias and unexplained pregnancy loss: an incident case-control study. Journal of Thrombosis and Haemostasis 7:306–311.
   PubMed Web of Science ®Google Scholar
• Patnaik MM, Haddad T, Morton CT. 2007. Pregnancy and thrombophilia. Expert Review of Cardiovascular Therapy 5:753–765.
   PubMedGoogle Scholar
• Pihusch R, Buchholz T, Lohse P, Rübsamen H, Rogenhofer N, Hasbargen U et al. 2001. Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester. American Journal of Reproductive Immunology 46:124–131.
   PubMed Web of Science ®Google Scholar
• Preston FE, Rosendaal FR, Walker ID, Briët E, Berntorp E, Conard J et al. 1996. Increased fetal loss in women with heritable thrombophilia. Lancet 348:913–916.
   PubMed Web of Science ®Google Scholar
• Ren A, Wang J. 2006. Methylentetrahydrofolate reductase C677T polymorphism and the risk of unexplained recurrent pregnancy loss: a meta-analysis. Fertility and Sterility 86:1716–1722.
   PubMed Web of Science ®Google Scholar
• Rey E, Kahn SR, David M, Shrier I. 2003. Thrombophilic disorders and fetal loss: a meta-analysis. Lancet 361:901–908.
   PubMed Web of Science ®Google Scholar
• Salafia C, Maier D, Vogel C, Pezzullo J, Burns J, Silberman L. 1993. Placental and decidual histology in spontaneous abortion: detailed description and correlations with chromosome number. Obstetrics and Gynecology 82:295–303.
   PubMed Web of Science ®Google Scholar
• Soltanghoraee H, Memariani T, Aarabi M, Hantoushzadeh S, Arefi S, Arabi M et al. 2007. Association of ACE, PAI-1 and coagulation factor XIII gene polymorphisms with recurrent spontaneous abortion in Iranian patients. Journal of Reproduction and Infertility 7:324–330.
   Google Scholar
• Sottilotta G, Oriana V, Latella C, Luise F, Piromalli A, Ramirez F et al. 2006. Genetic prothrombotic risk factors in women with unexplained pregnancy loss. Thrombosis Research 1117:681–684.
   Google Scholar
• Sun L, Lv H, Wei W, Zhang D, Guan Y. 2009. Angiotensin-converting enzyme D/I and plasminogen activator inhibitor-1 4G/5G gene polymorphisms are associated with increased risk of spontaneous abortion in women with polycystic ovarian syndrome. Journal of Endocrinological Investigation 33:77–82.
   PubMed Web of Science ®Google Scholar
• Ticconi C, Rotondi F, Veglia M, Pietropolli A, Bernardini S, Ria F et al. 2010. Antinuclear autoantibodies in women with recurrent pregnancy loss. American Journal of Reproductive Immunology 64:384–392.
   PubMed Web of Science ®Google Scholar
• Ticconi C, Mancinelli F, Gravina P, Federici G, Piccione E, Bernardini S. 2011. Beta-Fibrinogen G-455A polymorphisms and recurrent miscarriage. Gynecologic and Obstetric Investigation 71:198–201.
   PubMed Web of Science ®Google Scholar
• Vettriselvi V, Vijayalakshimi K, Paul SF, Venkatachalam P. 2008. Ace and MTHFR gene polymorphisms in unexplained recurrent pregnancy loss. Journal of Obstetrics and Gynaecology Research 34:301–306.
   PubMed Web of Science ®Google Scholar
• Wolf CE, Haubelt H, Pauer HU, Hinney B, Krome-Cesar C, Lagler TJ et al. 2003. Recurrent pregnancy loss and its relation to FV Leiden, FII G20210A and polymorphisms of plasminogen activator and plasminogen activator inhibitor. Pathophysiology of Haemostasis and Thrombosis 33:134–137.
   PubMedGoogle Scholar
• Zoller B, Dahlback B. 1994. Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis. Lancet 343:1536–1538.
   PubMed Web of Science ®Google Scholar