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Research Article

Evaluation of genotoxicity of Yanhuanglian dehydrocavidine (YHL-DC) in vitro and in vivo

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Pages 103-110 | Received 20 Apr 2009, Accepted 10 Jul 2009, Published online: 14 Dec 2009

References

  • Ashby, J. (1985). Is there a continuing role for the intraperitoneal injection route of exposure in short-term rodent genotoxicity assays? Mutat Res 156:239–243.
  • Bhakuni, D. S., Chatljrvedi, R. (1983). The alkaloids of Corydalis Meifolia. J Nat Prod 46:466–470.
  • Danford, N. (1984). Assays for the detection of chemically induced chromosome damage in cultured mammalian cells. In: Venitt, S., Parry, J. M. (Eds.), Mutagenicity testing—a practical approach ( pp 187–232). Oxford, UK: IRL Press.
  • Heddle, J. A., Hite, M., Kirkhart, B., Mavournin, K., MacGregor, J. T., Newell, G. W., et al. (1983). The induction of micronuclei as a measure of genotoxicity: a report of the US Environmental Protection Agency gene-tox program. Mutat Res 123:61–118.
  • Hui-Liang, L., Ting, H., Run-Hui, L., Chuan, Z., Hai-Sheng, C., Wei-Dong, Z. (2008). Alkaloids from Corydalis saxicola and their anti-hepatitis B virus activity. Chem Biodivers 5:777–783.
  • Huo, Y., Guo, C., Zhang, Q. Y., Chen, W. S., Zheng, H. C., Rahman, K., et al. (2007). Antinociceptive activity and chemical composition of constituents from Caragana microphylla seeds. Phytomedicine 14:143–146.
  • Heddle, J. A., Stuart, E., Salamone, M. F. (1984). The bone marrow micronucleus test. In: Kilbey, B. J., Legator, M., Nichols, W., Ramel, C. ( Eds.), Handbook of mutagenicity test procedures ( pp 441–457). Amsterdam, The Netherlands: Elsevier.
  • Ishidate, M., Jr., Yoshikawa, K. (1980). Chromosome aberration tests with Chinese hamster cells in vitro with and without metabolic activation—a comparative study on mutagens and carcinogens. Arch Toxicol (Suppl) 4:41–44.
  • Jiang W. (2006). Research progess of Corydalis saxicola Bunting. Chin Pharmaceut 5:1–3.
  • Li, C. X., Luo, J., Li, L., Cheng, M. L., Huang, N. H., Liu, J., et al. (2003). The collagenolytic effects of the traditional Chinese medicine preparation, Han-Dan-Gan-Le, contribute to reversal of chemical-induced liver fibrosis in rats. Life Sci 72:1563–1571.
  • Li, H. L., Zhang, W. D., Liu, R. H., Zhang, C., Hand, T., Wang, X. W., et al. (2006b). Simultaneous determination of four active alkaloids from a traditional Chinese medicine, Corydalis saxicola Bunting (Yanhuanglian), in plasma and urine samples by LC-MS-MS. J Chromatog Analyt Technol Biomed Life Sci 831:140–146.
  • Li, H. L., Zhang, W. D., Zhang, C., Liu, R. H., Wang, X. W., Wang, X. L., et al. (2006a). Bioavailabilty and pharmacokinetics of four active alkaloids of traditional Chinese medicine (Yanhuanglian) in rats following intravenous and oral administration. J Pharmaceut Biomed Anal 41:1342–1346.
  • Li, H. L., Han, T., Liu, R. H., Zhang, C., Chen, H. S., Zhang, W. D. (2008). Alkaloids from Corydalis saxicola and their antihepatitis B virus activity. Chem Biodivers 5:777–783.
  • Maron, D. M., Ames, B. N. (1983). Revised methods for the Salmonella mutagenicity test. Mutat Res 113:173–215.
  • OECD. (1997a). Guideline for the testing of chemicals. TG No. 471 “bacterial reverse mutation test.”D; Paris, France: OECD Publishing
  • OECD. (1997b). Guidelines for the testing of chemicals. TG No. 473 “in vitro mammalian chromosome aberration test.” Paris, France; OECD Publishing.
  • OECD. (1997c). Mammalian erythrocyte micronucleus test. In: OECD guideline for the testing of chemicals, Section 474, July 1997. Paris, France: OECD Publishing.
  • Preetha, S. P., Kanniappan, M., Selvakumar, E., Nagaraj, M., Varalakshmi, P. (2006). Lupeol ameliorates aflatoxin B1-induced peroxidative hepatic damage in rats. Comparative biochemistry and physiology. Toxicol Pharmacol CBP 143:333–339.
  • Sasakia, K., Hattab, S., Wadaa, K., Uedaa, N., Yoshimuraa, T., Endoa, T., et al. (2002). Effects of extract of Ginkgo biloba leaves and its constituents on carcinogen-metabolizing enzyme activities and glutathione levels in mouse liver. Life Sci 70:1657–1667.
  • SFDA. (2007). Guidelines for the testing of genotoxicity study of drugs [ZH]GPT2-1. Beijing, China: State Food and Drug Administration.
  • Sun, N. L., Lu, G. C., Yuan, B. J., Yuan, B. L. (2006). Progresses in Yanhuanglian research. Trad Chin Drug Res Clin Pharmacol 17:78–80.
  • Wei, J., Jiang, S., Jiang, Y., Qi, X., Tang, H. (2006). A review of Corydalis saxicola Bunting of medicinal plants. J Guangxi Acad Sci 22:108–111.

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