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Research Article

Reactive oxygen species and glutathione level changes by a proteasome inhibitor, MG132, partially affect calf pulmonary arterial endothelial cell death

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Pages 403-409 | Received 06 Nov 2009, Accepted 01 Dec 2009, Published online: 16 Jun 2010

References

  • Bassenge, E. (1996). Endothelial function in different organs. Prog Cardiovasc Dis 39:209–228.
  • Chen, T. J., Jeng, J. Y., Lin, C. W., Wu, C. Y., Chen, Y. C. (2006). Quercetin inhibition of ROS-dependent and -independent apoptosis in rat glioma C6 cells. Toxicology 223:113–126.
  • Dasmahapatra, G., Rahmani, M., Dent, P., Grant, S. (2006). The tyrphostin, adaphostin, interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism. Blood 107:232–240.
  • Han, Y. H., Kim, S. H., Kim, S. Z., Park, W. H. (2008a). Caspase inhibitor decreases apoptosis in pyrogallol-treated lung cancer Calu-6 cells via the prevention of GSH depletion. Int J Oncol 33:1099–1105.
  • Han, Y. H., Kim, S. Z., Kim, S. H., Park, W. H. (2007). Arsenic trioxide inhibits growth of As4.1 juxtaglomerular cells via cell cycle arrest and caspase-independent apoptosis. Am J Physiol Renal Physiol 293:F511–F520.
  • Han, Y. H., Kim, S. Z., Kim, S. H., Park, W. H. (2008b). Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine. Int J Oncol 33:205–213.
  • Han, Y. H., Kim, S. Z., Kim, S. H., Park, W. H. (2008c). Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine. Mol Cells 26:158–164.
  • Han, Y. H., Moon, H. J., You, B. R., Park, W. H. (2009). The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species, and GSH. Oncol Rep 22:215–221.
  • Irani, K. (2000). Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circ Res 87:179–183.
  • Jahngen-Hodge, J., et al. (1997). Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress. J Biol Chem 272:28218–28226.
  • Lee, D. H., Goldberg, A. L. (1998). Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol 8:397–403.
  • Ling, Y. H., Liebes, L., Zou, Y., Perez-Soler, R. (2003). Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to bortezomib, a novel proteasome inhibitor, in human H460 non-small-cell lung cancer cells. J Biol Chem 278:33714–33723.
  • Lum, H., Roebuck, K. A. (2001). Oxidant stress and endothelial cell dysfunction. Am J Physiol Cell Physiol 280:C719–C741.
  • Oberley, L. W., Oberley, T. D. (1988). Role of antioxidant enzymes in cell immortalization and transformation. Mol Cell Biochem 84:147–153.
  • Orlowski, R. Z. (1999). The role of the ubiquitin-proteasome pathway in apoptosis. Cell Death Differ 6:303–313.
  • Park, W. H., et al. (2000). Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis. Cancer Res 60:3065–3071.
  • Perez-Galan, P., Roue, G., Villamor, N., Montserrat, E., Campo, E., Colomer, D. (2006). The proteasome inhibitor, bortezomib, induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood 107:257–264.
  • Qiu, J. H., Asai, A., Chi, S., Saito, N., Hamada, H., Kirino, T. (2000). Proteasome inhibitors induce cytochrome c–caspase-3-like protease-mediated apoptosis in cultured cortical neurons. J Neurosci 20:259–265.
  • Voges, D., Zwickl, P., Baumeister, W. (1999). The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68:1015–1068.
  • Wallach-Dayan, S. B., Izbicki, G., Cohen, P. Y., Gerstl-Golan, R., Fine, A., Breuer, R. (2006). Bleomycin initiates apoptosis of lung epithelial cells by ROS but not by Fas/FasL pathway. Am J Physiol Lung Cell Mol Physiol 290:L790–L796.
  • Wu, H. M., Chi, K. H., Lin, W. W. (2002). Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production. FEBS Lett 526:101–105.
  • Yan, T., Li, S., Jiang, X., Oberley, L. W. (1999). Altered levels of primary antioxidant enzymes in progeria skin fibroblasts. Biochem Biophys Res Commun 257:163–167.
  • Yang, J., et al. (1997). Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275:1129–1132.

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