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Research Article

D-serine treatment induces oxidative stress in rat brain

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Pages 129-138 | Received 24 Mar 2010, Accepted 19 Apr 2010, Published online: 12 Feb 2011

References

  • Aebi, H. (1984). Catalase in vitro. Meth Enzymol 105:121–126.
  • Bauer, D., Hamacher, K., Bröer, S., Pauleit, D., Palm, C., Zilles, K., et al. (2005). Preferred stereoselective brain uptake of D-serine—a modulator of glutamatergic neurotransmission. Nucl Med Biol 32:793–797.
  • Bondy, S. C., Lee, D. K. (1993). Oxidative stress induced by glutamate receptor agonists. Brain Res 610:229–233.
  • Boveris, A., Chance, B. (1973). The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707–716.
  • Carone, F. A., Nakamura, S., Goldman, B. (1985). Urinary loss of glucose, phosphate, and protein by diffusion into proximal straight tubules injured by D-serine and maleic acid. Lab Invest 52:605–610.
  • Choi, D. W. (1988). Glutamate neurotoxicity and diseases of the nervious system. Neuron 1:623–624.
  • Choi, D. W., Rothman, S. M. (1990). The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 13:171–182.
  • Clifford, D. B., Zorumski, C. F., Olney, J. W. (1989). Ketamine and MK-801 prevent degeneration of thalamic neurons induced by focal cortical seizures. Exp Neurol 105:272–279.
  • Cock, H. R., Tong, X., Hargreaves, I. P., Heales, S. J., Clark, J. B., Patsalos, P. N., et al. (2002). Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat. Epilepsy Res 48:157–168.
  • Coyle, C. T., Puttfarcken, P. (1993). Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:689–695.
  • da Silva de, B., Leipnitz, G., Seminotti, B., Fernandes, C. G., Beskow, A. P., Amaral, A. U., et al. (2009). D-serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats. Brain Res 1256:34–42.
  • Davidson, M. E., Kerepesi, L. A., Soto, A., Chan V. T. (2009). D-serine exposure resulted in gene expression changes implicated in neurodegenerative disorders and neuronal dysfunction in male Fischer 344 rats. Arch Toxicol 83:747–762.
  • Di Stefano, A., Frosali, S., Leonini, A., Ettorre, A., Priora, R., Di Simplicio, F. C., et al. (2006). GSH depletion, protein S-glutathionylation, and mitochondrial transmembrane potential hyperpolarization are early events in initiation of cell death induced by a mixture of isothiazolinones in HL60 cells. Biochim Biophys Acta 1763:214–225.
  • Draper, H. H., Hadley, M. (1990). Malondialdehyde determination as index of lipid peroxidation. Meth Enzymol 186:421–431.
  • Dreiem, A., Seegal, F. G. (2007). Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent. Neurotoxicol 28:720–726.
  • Foster, A. C., Willis, C. L., Tridgett, R. (1990). Protection against N-methyl-D-aspartate receptor-mediated neuronal degeneration ın rat brain by 7-chlorokynurenate and 3-amino-1-hydroxypyrrolid-2-1, antagonists at the allosteric site for glycine. Eur J Neurosci 2:270–277.
  • Franco, R., Cidlowski, J. A. (2006). SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis. J Biol Chem 281:29542–29557.
  • Fujii, K., Maeda, K., Hikida, T., Mustafa, A. K., Balkissoon, R., Xia, J., et al. (2006). Serine racemase binds to PICK1: potential relevance to schizophrenia. Mol Psychiatry 11:150–157.
  • Furukawa, H., Gouaux, E. (2003). Mechanisms of activation, inhibition, and specificity: crystal structures of the NMDA receptor, NR1, ligand-binding core. EMBO J 22:2873–2885.
  • Garcia, E., Limon, D., Perez-De La Cruz, V., Giordano, M., Diaz-Munoz, M., Maldonado, P. D., et al. (2008). Lipid peroxidation, mitochondrial dysfunction, and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine. Free Radic Res 42:892–902.
  • González-Hernández, J. C., Aguilera-Aguirre, L., Pérez-Vázquez, V., Ramírez, J., Clemente-Guerrero, M., Cortés-Rojo, C., et al. (2003). Effect of D-amino acids on some mitochondrial functions in rat liver. Aminoacids 24(1–2):163–169.
  • Hammond, C. L., Marchan, R., Krance, S. M., Ballatori, N. (2007). Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. J Biol Chem 282:14337–14347.
  • Hashimoto, A., Chiba, Y. (2004). Effects of systemic administration of D-serine on the levels of D- and L-serine in several brain areas and periphery of rat. Eur J Pharm 495:153–158.
  • Hashimoto, A., Nishikawa, T., Hayashi, T., Fujii, N., Harada, K., Oka, T., et al. (1992). The presence of free D-serine in rat brain. FEBS Lett 296:33–36.
  • Karadeniz, H., Armagan, G., Erdem, A., Turunc, E., Caliskan, A., Kanit, L., et al. (2009). The comparison of electrochemical assay and agarose gel electrophoresis for the determination of DNA damage induced by kainic acid. Electroanalysis 21:2468–2476.
  • Katsuki, H., Nonaka, M., Shirakawa, H., Kume, T., Akaike, A. (2004). Endogenous D-serine is involved in induction of neuronal death by N-methyl-D-aspartate and simulated ischemia in rat cerebrocortical slices. J Pharm Exp Ther 311:836–844.
  • Katsuki, H., Watanabe, Y., Fujimoto, S., Kume, T., Akaike, A. (2007). Contribution of endogenous glycine and D-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures. Life Sci 81:740–749.
  • Kleckner, N. W., Dingledine, R. (1988). Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241:835–837.
  • Kowaltowski, A. J., Vercesi, A. E. (1999). Mitochondrial damage induced by conditions of oxidative stress. Free Radic Biol Med 26(3–4):463–471.
  • Lowry, O. H., Rosenbrough, N. J., Farr, A. L., Randall, R. J. (1951). Protein measurement with the folin-phenol reagent. J Biol Chem 193:265–375.
  • Marini, H., Altavilla, D., Bellomo, M., Adamo, E. B., Marini, R., Laureanti, F., et al. (2004). Modulation of IL-1 beta gene expression by lipid peroxidation inhibition after kainic acid-induced rat brain injury. Exp Neurol 188:178–186.
  • Matsui, T., Sekiguchi, M., Hashimoto, A., Tomita, U., Nishikawa, T., Wada, K. (1995). Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration. J Neurochem 65:454–458.
  • Merad-Boudia, M., Nicole, A., Santiard-Baron, D., Saillé, C., Ceballos-Picot, I. (1998). Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson’s disease. Biochem Pharmacol 56:645–655.
  • Montiel, T., Quiroz-Baez, R., Massieu, L., Arias, C. (2006). Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: protection by antioxidants. Exp Neurol 200:496–508.
  • Mothet, J. P., Parent, A. T., Wolosker, H., Brady, R.O., Jr., Linden, D. J., Ferris, C. D., et al. (2000). D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A 97:4926–4931.
  • Oldendorf, W. H. (1971). Brain uptake of radiolabeled aminoacids, amines, and hexoses after arterial injection. Am J Physiol 221:1629–1639.
  • Owen, M. J., Craddock, N., O’Donovan, M. C. (2005). Schizophrenia: genes at last? Trends Genet 21:518–525.
  • Patel, J., Zinkand, W. C., Thompson, C., Keith, R., Salama, A. (1990). Role of glycine in the N-methyl-D-aspartate–mediated neuronal cytotoxicity. J Neurochem 54:849–854.
  • Patel, M. (2004). Mitochodrial dysfunction and oxidative stress: causes and consequence of epilectic seizures. Free Radic Biol Med 37:1951–1962.
  • Perez-De La Cruz, V., Gonzales-Cortes, C., Galvan-Arzate, S., Medina-Campos, O. N., Perez-Severiano, F., Ali, S. F., et al. (2005). Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington’s disease in rats: protective role of iron porphryrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III). Neuroscience 135:463–474.
  • Reznick, A. Z., Packer, L. (1994). Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Meth Enzymol 233:357–363.
  • Ribeiro, C. S., Reis, M., Panizzutti, R., de Miranda, J., Wolosker, H. (2002). Glial transport of the neuromodulator, D-serine. Brain Res 929:202–209.
  • Rothman, S. M., Thurston, J. H., Hauhart, R. E. (1987). Delayed neurotoxicity of excitatory amino acids in vitro. Neurosci 22:471–180.
  • Shleper, M., Kartvelishvily, E., Wolosker, H. (2005). D-serine is the dominant endogenous coagonist for NMDA-receptor neurotoxicity in organotypic hippocampal slices. J Neurosci 25:9413–9417.
  • Silbernagl, S., O’Donovan, D. J., Völker, K. (1997). D-serine nephrotoxicity is mediated by oxidative damage [Abstract]. Pflüegers Arch 433:R37.
  • Silva-Adaya, D., Pérez-De La Cruz, V., Herrera-Mundo, M. N., Mendoza-Macedo, K., Villeda-Hernández, J., Binienda, Z., et al. (2008). Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine. J Neurochem 105:677–689.
  • Stípek, S., Stastný, F., Pláteník, J., Crkovská, J., Zima, T. (1997). The effect of quinolinate on rat brain lipid peroxidation is dependent on iron. Neurochem Int 30:233–237.
  • Tsai, G., Yang, P., Chung, L. C., Lange, N., Coyle, J. T. (1998). D-serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry 44:1081–1089.
  • Turrens, J. P. (1997). Superoxide production by the mitochondrial respiratory chain. Biosci Rep 17:3–8.
  • Wang, D., Kreutzer, D.A., Essigmann, J. M. (1998). Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions. Mutat Res 400(1–2):99–115.
  • Wolosker, H. (2007). NMDA receptor regulation by D-serine: new findings and perspectives. Mol Neurobiol 36:152–164.
  • Wu, S. Z., Bodles, A. M., Porter, M. M., Griffin, W. S. T., Basile, A. S., Barger, S. W. (2004). Induction of serine rasemase expression and D-serine release from microglia by amyloid β-peptide. J Neuroinf 1:2–11.
  • Zhang, J., Perry, G., Smith, M. A., Robertson, D., Olson, S. J., Graham, D. G., et al. (1999). Parkinson’s disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 154:1423–1429.

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