Recombinant human erythropoietin prevents cisplatin-induced genotoxicity in rat liver and heart tissues via an antioxidant process

References

• Ali, B. H., Al Moundhri, M. S. (2006). Agents ameliorating or augmenting the nephrotoxicity of cisplatin and other platinum compounds: a review of some recent research. Food Chem Toxicol 44:1173–1183.
   PubMed Web of Science ®Google Scholar
• Antunes, L. M. G., Darin, J. D. C., Bianchi, M. L. P. (2000). Protective effects of vitamin C against cisplatin-induced nephrotoxicity and lipid peroxidation in adult rats. Pharmacol Res 41:405–411.
   PubMed Web of Science ®Google Scholar
• Antunes, L. M. G., Darin, J. D. C., Bianchi, M. L. P. (2001). Effects of the antioxidants curcumin or selenium on cisplatin-induced nephrotoxicity and lipid peroxidation in rats. Pharmacol Res 43:145–150.
   PubMed Web of Science ®Google Scholar
• Banath, J. P., Kim, A., Olive, P. (2002). Overnight lysis improves the efficiency of DNA damage detection in the alkaline comet assay. Radiat Res 1155:564–571.
   Google Scholar
• Bradford, M. M. (1976). A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254.
   PubMed Web of Science ®Google Scholar
• Chatterjee, P. K. (2005). Pleiotropic renal actions of erythropoietin. Lancet 365:1890–1892.
   PubMed Web of Science ®Google Scholar
• Chvetzoff, G., Bonotte, B., Chauffert, B. (1998). Anticancer chemotherapy. Prevention of toxicity. Presse Med 27:2106–2112.
   PubMed Web of Science ®Google Scholar
• Clairbone, A. (1985). Catalase activity. In: Handbook of methods for oxygen radical research ( pp. 283–284). Boca Raton, Florida, USA: CRC Press.
   Google Scholar
• Collins, A. R., Dusinska, M., Gedik, C. M., Stetina, R. (1996). Oxidative damage to DNA: do we have a reliable biomarker? Environ Health Perspect 104:465–469.
   PubMed Web of Science ®Google Scholar
• Dalle-Donne, I., Giustarini, D., Colombo, R., Rossi, R., Milzani, A. (2003a). Protein carbonylation in human diseases. Trends Mol Med 9:169–176.
   PubMed Web of Science ®Google Scholar
• Dalle-Donne, I., Rossi, R., Giustarini, D., Milzani, A., Colombo, R. (2003b). Protein carbonyl groups as biomarkers of oxidative damage in human disease. Clin Chim Acta 329:23–38.
   PubMed Web of Science ®Google Scholar
• Dos Santos, N. A., Martins, N. M., Curti, C., Pires Bianchi Mde, L., Dos Santos, A. C. (2007). Dimethylthiourea protects against mitochondrial oxidative damage induced by cisplatin in liver of rats. Chem Biol Interact 170:177–186.
   PubMed Web of Science ®Google Scholar
• El-Awady, E. S. E., Moustafa, Y. M., Abo-Elmatty, D. M., Radwan, A. (2011). Cisplatin-induced cardiotoxicity: mechanisms and cardioprotective strategies. Eur J Pharmacol 650:335–341.
   PubMed Web of Science ®Google Scholar
• Fadillioglu, E., Erdogan, H., Sogut, S., Kuku, I. (2003). Protective effects of erdosteine against doxorubicin-induced cardioomyopathy in rats. J Appl Toxicol 23:71–74.
   PubMed Web of Science ®Google Scholar
• Fadillioglu, E., Erdogan, H. (2003). Effects of erdosteine treatment against doxorubicin-induced toxicity through erythrocyte and plasma oxidant/antioxidant status in rat. Pharmacol Res 47:317–322.
   PubMed Web of Science ®Google Scholar
• Hodges, V. M., Rainey, S., Lappin, T. R., Maxwell, A. P. (2007). Pathophysiology of anemia and erythrocytosis. Crit Rev Oncol Hematol 64:139–158.
   PubMed Web of Science ®Google Scholar
• Iraz, M., Ozerol, E., Gulec, M., Tasdemir, S., Idiz, N., Fadillioglu, E., et al. (2006). Protective effect of caffeic acid phenethyl ester (CAPE) administration on cisplatin-induced oxidative damage to liver in rat. Cell Biochem Funct 24:357–361.
   PubMed Web of Science ®Google Scholar
• King, P. D., Perry, M. C. (2001). Hepatotoxicity of chemotherapy. Oncologist 6:162–176.
   PubMed Web of Science ®Google Scholar
• Kintzel, P. E. (2001). Anticancer drug-induced kidney disorders. Drug Saf 24:19–38.
   PubMed Web of Science ®Google Scholar
• Koc, A., Duru, M., Ciralik, H., Akcan, R., Sogut, S. (2005). Protective agent, erdosteine, against cisplatin-induced hepatic oxidant injury in rats. Mol Cell Biochem 278:79–84.
   PubMed Web of Science ®Google Scholar
• Kumral, A., Baskin, H., Gokmen, N., Yilmaz, O., Genc, K., Genc, S. (2004). Selective inhibition of nitric oxide in hypoxic-ischemic brain model in newborn rats: is it an explanation for the protective role of erythropoietin? Biol Neonate 85:51–54.
   PubMedGoogle Scholar
• Kuriyama, S., Tomonari, H., Yoshida, H., Hashimoto, T., Kawaguchi, Y., Sakai, O. (1997). Reversal of anemia by erythropoietin therapy retards the progression of chronic renal failure, especially in nondiabetic patients. Nephron 77:176–185.
   PubMed Web of Science ®Google Scholar
• Li, F., Chong, Z. Z., Maiese, K. (2004). Erythropoietin on a tightrope: balancing neuronal and vascular protection between intrinsic and extrinsic pathways. Neurosignals 13:265–289.
   PubMed Web of Science ®Google Scholar
• Lieberthal, W., Triaca, V., Levine, J. (1996). Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs necrosis. Am J Physiol 240:700–708.
   Google Scholar
• Loehrer, P. J., Einhom, L. H. (1984). Cisplatin. Ann Intern Med 100:704–713.
   PubMed Web of Science ®Google Scholar
• Maiese, K., Li, F., Chong, Z. Z. (2004). Erythropoietin in the brain: can the promise to protect be fulfilled? Trends Pharmacol Sci 25:577–583.
   PubMed Web of Science ®Google Scholar
• Maiese, K., Li, F., Chong, Z. Z. (2005). New avenues of exploration for erythropoietin. JAMA 293:90–95.
   PubMed Web of Science ®Google Scholar
• Mansour, H. H., Hafez, H. F., Fahmy, N. M. (2006). Silymarin modulates cisplatin induced oxidative stress and hepatotoxicity in rats. J Biochem Mol Biol 39:656–561.
   PubMedGoogle Scholar
• Meister, A., Anderson, M. E. (1983). Glutathione. Ann Rev Biochem 52:711–760.
   PubMed Web of Science ®Google Scholar
• Mercier, Y., Gatellier, P., Renerre, M. (2004). Lipid and protein oxidation in vitro, and antioxidant potential in meat from Charolais cows finished on pasture or mixed diet. Meat Sci 66:467–473.
   PubMed Web of Science ®Google Scholar
• Mora, L. O., Antunes, L. M., Francescato, H. D., Bianchi, M. I. (2003). The effects of oral glutamine on cisplatin-induced nephrotoxicity in rats. Pharmacol Res 47:517–522.
   PubMed Web of Science ®Google Scholar
• Nemoto, T., Yokota, N., Keane, W. F., Rabb, H. (2001). Recombinant erythropoietin rapidly treats anemia in ischemic acute renal failure. Kidney Int 59:246–251.
   PubMed Web of Science ®Google Scholar
• Packer, L., Landvik, S. (1990). Vitamin E in biological systems. In: Emerit, I., Packer, L., Auclair, C. (Eds.), Antioxidants in therapy and preventive medicine (pp. 93–104). New York: Plenum.
   Google Scholar
• Pai, V. B., Nahata, M. C. (2000). Cardiotoxicity of chemotherapeutic agents: incidence, treatment, and prevention. Drug Saf 22:263–302.
   PubMed Web of Science ®Google Scholar
• Picada, J. N., Flores, D. G., Zettler, C. G., Marroni, N. P., Roesler, R., Henriques, J. A. P. (2003). DNA damage in brain cells of mice treated with an oxidized form of apomorphine. Brain Res Mol Brain Res 114:80–85.
   PubMedGoogle Scholar
• Pratibha, R., Sameer, R., Rataboli, P. V., Bhiwgade, D. A., Dhume, C. Y. (2006). Enzymatic studies of cisplatin induced oxidative stress in hepatic tissue of rats. Eur J Pharmacol 532:290–293.
   PubMed Web of Science ®Google Scholar
• Saad, A. A., Youssef, M. I., El-Shennawy, L. K. (2009). Cisplatin induced damage in kidney genomic DNA and nephrotoxicity in male rats: the protective effect of grape seed proanthocyanidin extract. Food Chem Toxicol 47:1499–1506
   PubMed Web of Science ®Google Scholar
• Schmeding, M., Neumann, U. P., Boas-Knoop, S., Spinelli, A., Neuhaus, P. (2007). Erythropoietin reduces ischemia-reperfusion injury in the rat liver. Eur Surg Res 39:189–197.
   PubMed Web of Science ®Google Scholar
• Sian, J., Dexter, D. T., Cohen, G., Jenner, P. G., Marsden, C. D. (1997). Comparison of HPLC and enzymatic recycling assays for the measurement of oxidized glutathione in rat brain. J Pharmacol 49:332–335.
   Google Scholar
• Singh, N., McCoy, M., Tice, R., Schneider, E. (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–191.
   PubMed Web of Science ®Google Scholar
• Solaroglu, I., Solaroglu, A., Kaptanoglu, E., Dede, S., Haberal, A., Beskonakli, E. (2003). Erythropoietin prevents ischemia-reperfusion from inducing oxidative damage in fetal rat brain. Childs Nerv Syst 19:19–22.
   PubMed Web of Science ®Google Scholar
• Sun, Y., Zhou, C., Polk, P., Nanda, A., Zhang, J. H. (2004). Mechanisms of erythropoietin-induced brain protection in neonatal hypoxia-ischemia rat model. J Cereb Blood Flow Metab 24:259–270.
   PubMed Web of Science ®Google Scholar
• Tice, R. R., Agurell, E., Anderson, D., Burlinson, B., Hartmann, A., Kobayashi, Y., et al. (2000). Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35:206–221.
   PubMed Web of Science ®Google Scholar
• Vina, J., Sastre, M., Asensi, L., Packer, L. (1995). Assay of blood glutathione oxidation during physical exercise. Meth Enzymol 251:237–243.
   PubMed Web of Science ®Google Scholar
• Yüce, A., Atessahin, A. A., Çeribasi, A. O., Aksakal, M. (2007). Ellagic acid prevents cisplatin-induced oxidative stress in liver and heart tissue of rats. Basic Clin Pharmacol Toxicol 101:345–349.
   PubMed Web of Science ®Google Scholar
• Zicca, A., Cafaggi, S., Mariggiò, M. A., Vannozzi, M. O., Ottone, M., Bocchini, V., et al. (2002). Reduction of cisplatin hepatotoxicity by procainamide hydrochloride in rats. Eur J Pharmacol 442:265–272.
   PubMed Web of Science ®Google Scholar