Advanced search
Publication Cover
Drug and Chemical Toxicology Volume 35, 2012 - Issue 2
Submit an article Journal homepage
234
Views
33
CrossRef citations to date
0
Altmetric
Research Article

Toxicity induced by emodin on zebrafish embryos

Qiuxia He;Biology Institute of Shandong Academy of Sciences, Jinan, Shandong, China
,
Kechun Liu;Key Laboratory for Biosensors of Shandong Province, Jinan, Shandong, ChinaCorrespondence[email protected]
,
Sifeng Wang;Biology Institute of Shandong Academy of Sciences, Jinan, Shandong, China
,
Hairong Hou;Key Laboratory for Biosensors of Shandong Province, Jinan, Shandong, China
,
Yanqiang Yuan;Biology Institute of Shandong Academy of Sciences, Jinan, Shandong, China
&
Ximin Wang;Key Laboratory for Biosensors of Shandong Province, Jinan, Shandong, China
Pages 149-154 | Received 16 Feb 2011, Accepted 07 Apr 2011, Published online: 11 Aug 2011

References

  • Bresolin, T., de Freitas Rebelo, M., Celso Dias Bainy, A. (2005). Expression of PXR, CYP3A, and MDR1 genes in liver of zebrafish. Comp Biochem Physiol C Toxicol Pharmacol 140:403–407.
  • David, A., Pancharatna, K. (2009). Developmental anomalies induced by a non-selective COX inhibitor (ibuprofen) in zebrafish (Danio rerio). Environ Toxicol Phar 27:390–395.
  • Feng, Y., Huang, S. L., Dou, W., Zhang, S., Chen, J. H., Shen, Y., et al. (2010). Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice. Br J Pharmacol 161:113–126.
  • Haendel, M. A., Tilton, F., Bailey, G. S., Tanguay, R. L. (2004). Developmental toxicity of the dithiocarbamate pesticide sodium metam in Zebrafish. Toxicol Sci 81:390–400.
  • Huang, Q., Lu, G., Shen, H. M., Chung, M. C., Ong, C. N. (2007). Anti-cancer properties of anthraquinones from rhubarb. Med Res Rev 27:609–630.
  • Jahnke, G. D., Price, C. J., Marr, M. C., Myers, C. B., George, J. D. (2004). Developmental toxicity evaluation of emodin in rats and mice. Birth Defects Res (Part B) 71:89–101.
  • Kimmel, C., Ballard, W. W., Kimmel, S. R., Ullmann, B., Schilling, T. F. (1995). Stages of embryonic development in the zebrafish. Dev Dyn 203:253–310.
  • Mantani, N., Kogure, T., Sakai, S., Kainuma, M., Kasahara, Y., Niizawa, A., et al. (2002). A comparative study between excess-dose users and regular-dose users of rhubarb contained in Kampo medicines. Phytomedicine 9:373–76.
  • McGrath, P., Li, C. Q. (2008). Zebrafish: a predictive model for assessing drug-induced toxicity. Drug Discov Today 13:394–401.
  • Meng, G., Liu, Y., Lou, C., Yang, H. (2010). Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-kappaB activation by disrupting lipid rafts in CD14-negative endothelial cells. Br J Pharmacol 161:1628–1644.
  • Sui, F., Huo, H. R., Zhang, C. B., Yang, N., Guo, J. Y., Du, X. L., Zhao, B. S., et al. (2010). Emodin down-regulates expression of TRPV1 mRNA and its function in DRG neurons in vitro. Am J Chin Med 38:789–800.
  • Tseng, H. P., Hseu, T. H., Buhler, D. R., Wang, W. D., Hu, C. H. (2005). Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva. Toxicol Appl Pharmacol 205:247–58.
  • Wang, Q. J., Cai, X. B., Liu, M. H., Hu, H., Tan, X. J., Jing, X. B. (2010a). Apoptosis induced by emodin is associated with alterations of intracellular acidification and reactive oxygen species in EC-109 cells. Biochem Cell Biol 88:767–774.
  • Wang, S. F., Liu, K. C., Wang, X., He, Q. X., Chen, X. Q. (2010b). Toxic effects of celastrol on embryonic development of zebrafish (Danio rerio). Drug Chem Toxicol 34:61–65.
  • Westerfield, M. (1995). The zebrafish book. Eugene, Oregon, USA: University of Oregon Press.
  • Zhou, S., Dong, Q., Li, S., Guo, J., Wang, X., Zhu, G. (2009). Developmental toxicity of cartap on zebrafish embryos. Aquat Toxicol 95:339–346.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.