481
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Antigenotoxic and antioxidant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells

, , , , &
Pages 66-73 | Received 16 Oct 2014, Accepted 04 Mar 2015, Published online: 31 Mar 2015

References

  • Aluko BT, Oloyede OI, Afolayan AJ. (2013). Polyphenolic contents and free radical scavenging potential of extracts from leaves of Ocimum americanum L. Pak J Biol Sci 16:22–30
  • Anderson RF, Amarasinghe C, Fisher LJ, et al. (2000). Reduction in free-radical-induced DNA strand breaks and base damage through fast chemical repair by flavonoids. Free Rad Res 33:91–103
  • Arora A, Nair MG, Strasburg GM. (1998). Structure–activity relationships for antioxidant activities of a series of flavonoids in a liposomal system. Free Rad Biol Med 24:1355–1363
  • Arul D, Subramanian P. (2013). Naringenin (citrus flavonone) induces growth inhibition, cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. Pathol Oncol Res 19:763–770
  • Aycicek A, Ipek A. (2008). Maternal active or passive smoking causes oxidative stress in cord blood. Eur J Pediatr 167:81–85
  • Behravan J, Mosafa F, Soudmand N, et al. (2011). Protective effects of aqueous and ethanolic extracts of Portulaca oleracea L. aerial parts on H2O2-induced DNA damage in lymphocytes by comet assay. J Acupunct Meridian Stud 4:193–197
  • Bjelland S, Seeberg E. (2003). Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutat Res 531:37–80
  • Bokkenheuser VD, Scholes JV, Klinger MM, Winter J. (1991). Natural anticancerogenics. Acta Chir Eur J Surg 71–76
  • Çelik, H, Koşar, M. 2012. Inhibitory effects of dietary flavonoids on purified hepatic NADH-cytochrome b5 reductase: structure–activity relationships. Chem Biol Interact 197:103–109
  • Chanet A, Milenkovic D, Deval C, et al. (2012). Naringin, the major grapefruit flavonoid, specifically affects atherosclerosis development in diet-induced hypercholesterolemia in mice. J Nutr Biochem 23:469–477
  • Cheel J, Theoduloz C, Rodríguez J, Schmeda-Hirschmann G. (2005). Free radical scavengers and antioxidants from lemongrass (Cymbopogon citratus (DC.) Stapf.). J Agric Food Chem 53:2511–2517
  • Collins AR, Ai-Guo M, Duthie SJ. (1995). The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells. Mutat Res 336:69–77
  • Dikilitas M, Guldur ME, Deryaoglu A, Ozcan E. (2011). Antioxidant and oxidant levels of pepper (Capsicum annuum cv.‘Charlee’) infected with pepper mild mottle virus. Not Bot Horti Agrobo 39:58–63
  • Dikilitas M, Kocyigit A. (2012). Assessment of computerized and manual analysis of slides processed in single cell gel electrophoresis assay. Fresenius Environ Bull 21:2981–2987
  • Diplock AT. (1991). Antioxidant nutrients and disease prevention: an overview. Am J Clin Nutr 53:189s–193s
  • Ebrahimi A, Schluesener H. (2012). Natural polyphenols against neurodegenerative disorders: potentials and pitfalls. Ageing Res Rev 11:329–345
  • Erel O. (2004). A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem 37:277–285
  • Erel O. (2005). A new automated colorimetric method for measuring total oxidant status. Clin Biochem 38:1103–1111
  • Esterbauer H, Schaur RJ, Zollner H. (1991). Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Rad Biol Med 11:81–128
  • Galati G, Sabzevari O, Wilson JX, O'Brien PJ. (2002). Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology 177:91–104
  • Giorgio M, Trinei M, Migliaccio E, Pelicci PG. (2007). Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat Rev Mol Cell Biol 8:722–728.
  • Halliwell B. (1991). Reactive oxygen species in living systems: source, biochemistry, and role in human disease. Am J Med 91:S14–S22
  • Halliwell B. (1994). Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? The Lancet 344:721–724
  • Halliwell B, Gutteridge JM. (1992). Biologically relevant metal ion-dependent hydroxyl radical generation. An update. FEBS Lett 307:108–112
  • Harma M, Harma M, Erel O. (2003). Increased oxidative stress in patients with hydatidiform mole. Swiss Med Weekly 133:563–566
  • Harma M, Harma M, Erel O. (2005). Measurement of the total antioxidant response in preeclampsia with a novel automated method. Eur J Obstetr Gynecol Reprod Biol 118:47–51
  • Hazra TK, Das A, Das S, et al. (2007). Oxidative DNA damage repair in mammalian cells: a new perspective. DNA Repair 6:470–480
  • Holley A, Cheeseman K. (1993). Measuring free radical reactions in vivo. Br Med Bull 49:494–505
  • Kanno S, Tomizawa A, Ohtake T, et al. (2006). Naringenin-induced apoptosis via activation of NF-kappaB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells. Toxicol Lett 166:131–139
  • Kassie F, Parzefall W, Knasmuller S. (2000). Single cell gel electrophoresis assay: a new technique for human biomonitoring studies. Mutat Res 463:13–31
  • Kaur P, Kaur S, Kumar N, et al. (2009). Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L. Toxicol In Vitro 23:680–686
  • Kocyigit A, Selek S, Celik H, Dikilitas M. (2011). Mononuclear leukocyte DNA damage and oxidative stress: the association with smoking of hand-rolled and filter-cigarettes. Mutat Res 721:136–141
  • Kumar A, Chattopadhyay S. (2007). DNA damage protecting activity and antioxidant potential of pudina extract. Food Chem 100:1377–1384
  • Lee YR, Kim DH. (2006). A new route to the synthesis of pyranoflavone and pyranochalcone natural products and their derivatives. Synthesis 2006:603–608
  • Liu YL, Ho DK, Cassady JM, et al. (1992). Isolation of potential cancer chemopreventive agents from eriodictyon-californicum. J Nat Prod 55:357–363
  • Liu HL, Jiang WB, Xie MX. (2010). Flavonoids: recent advances as anticancer drugs. Recent Pat AntiCancer Drug Discov 5:152–164
  • Majo DD, Giammanco M, Guardia ML, et al. (2005). Flavanones in citrus fruit: structure–antioxidant activity relationships. Food Res Int 38:1161–1166
  • Maroziene A, Nemeikaite-Čeniene A, Vidžiunaite R, Čenas N. (2012). Correlation between mammalian cell cytotoxicity of flavonoids and the redox potential of phenoxyl radical/phenol couple. Acta Biochim Pol 59:299–305
  • Mosmann T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55–63
  • Olsen HT, Stafford GI, Van Staden J, et al. (2008). Isolation of the MAO-inhibitor naringenin from Mentha aquatica L. J Ethnopharmacol 117:500–502
  • Ordoudi SA, Tsimidou MZ. (2006). Crocin bleaching assay (CBA) in structure–radical scavenging activity studies of selected phenolic compounds. J Agric Food Chem 54:9347–9356
  • Özyürek M, Akpinar D, Bener M, et al. (2014). Novel oxime based flavanone, naringin-oxime: synthesis, characterization and screening for antioxidant activity. Chem Biol Interact 212:40–46
  • Park JH, Jin CY, Lee BK, et al. (2008). Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells. Food Chem Toxicol 46:3684–3690
  • Raza SS, Khan MM, Ahmad A, et al. (2013). Neuroprotective effect of naringenin is mediated through suppression of NF-kappaB signaling pathway in experimental stroke. Neuroscience 230:157–171
  • Reddy TK, Seshadri P, Reddy K, et al. (2008). Effect of Terminalia arjuna extract on adriamycin-induced DNA damage. Phytother Res 22:1188–1194
  • Rice-Evans CA, Miller NJ, Paganga G. (1996). Structure–antioxidant activity relationships of flavonoids and phenolic acids. Free Rad Biol Med 20:933–56
  • Sailaja Rao P, Kalva S, Yerramilli A, Mamidi S. (2011). Free radicals and tissue damage: role of antioxidants. Free Rad Antioxidants 1:2–7
  • Sakihama Y, Mano JI, Sano S, et al. (2000). Reduction of phenoxyl radicals mediated by monodehydroascorbate reductase. Biochem Biophys Res Commun 279:949–954
  • Singh NP, Mccoy MT, Tice RR, Schneider EL. (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–191
  • Turkkan B, Ozyurek M, Bener M, et al. (2012). Synthesis, characterization and antioxidant capacity of naringenin-oxime. Spectrochim Acta A Mol Biomol Spectrosc 85:235–240
  • Valko M, Leibfritz D, Moncol J, et al. (2007). Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44–84
  • Yamamoto Y, Brodsky MH, Baker JC, Ames BN. (1987). Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography. Anal Biochem 160:7–13
  • Zegura B, Dobnik D, Niderl MH, Filipic M. (2011). Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells. Environ Toxicol Pharmacol 32:296–305

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.