Advanced search
Publication Cover
Drug and Chemical Toxicology Volume 8, 1985 - Issue 1-2
Submit an article Journal homepage
66
Views
84
CrossRef citations to date
0
Altmetric
Research Article

Chronic Toxicity and Oncogenicity Bioassay of Inhaled Ethyl Acrylate in Fischer 344 Rats and B6c3f1 Mice

R. R. Miller Mammalian and Environmental Toxicology, Research Laboratory, Dow Chemical, Midland, Michigan, 48640, USA
,
J. T. Young Mammalian and Environmental Toxicology, Research Laboratory, Dow Chemical, Midland, Michigan, 48640, USA
,
R. J. Kociba Mammalian and Environmental Toxicology, Research Laboratory, Dow Chemical, Midland, Michigan, 48640, USA
,
D. G. Keyes Mammalian and Environmental Toxicology, Research Laboratory, Dow Chemical, Midland, Michigan, 48640, USA
,
K. M. Bodner Mammalian and Environmental Toxicology, Research Laboratory, Dow Chemical, Midland, Michigan, 48640, USA
,
L. L. Calhoun Mammalian and Environmental Toxicology, Research Laboratory, Dow Chemical, Midland, Michigan, 48640, USA
&
J. A. Ayres Health and Environmental Sciences U.S.A., Midland, Michigan, 48640, USA
 show all
Pages 1-42 | Published online: 27 Sep 2008

References

  • Autian J. Structure-toxicity relationships of acrylic monomers. Env. Health Persp. (1975); 11: 141–152
  • Stahl W. H. Compilation of Odor and Taste Threshold Value Data. American Society of Testing and Materials, Philadelphia, PA 1983
  • Young J. T. Histopathologic examination of the rat nasal cavity. Fundam. and Appl. Toxicol. (1981); 1: 309–312
  • Siegel S. Non-Parametric Statistics for the Behavioral Sciences. McGraw-Hill Book Company, Inc., New York 1956
  • Miller R. G. Simultaneous Statistical Inference. McGraw-Hill, New York 1966
  • Armitage P. Statistical Methods in Medical Research. John Wiley and Sons, New York, NY 1973
  • Breslow N. A generalized Kruskal-Wallis test for comparing K samples subject to unequal patterns of censorship. Biometrik. (1970); 57: 579–594
  • Fleiss J. L. Statistical methods for rates and proportions. John Wiley and Sons, New York, NY 1973
  • Mantel N. Chi-square tests with one degree of freedom; Extensions of the Mantel-Haenszel Procedure. J. American Statistical Association. 1963
  • Winer B. H. Statistical Principles in Experimental Design. McGraw-Hill, New York 1971
  • Steel R. G.D., Torrie H. H. Principles and Procedures of Statistics. McGraw-Hill, New York 1960
  • Ward J. M., Goodman D. G., Squire R. A., Chen K. C, Linhart M. S. Neoplastic and nonneoplastic lesions in aging (C57BL/6N ± C3H/HeN0 F1 (B6C3F1) Mice. J. Nat. Cancer Inst. (1979); 631(3)849–854
  • Dunn T. B. Normal and pathologic anatomy of the reticular tissue in laboratory mice, with a classification and discussion of neoplasma. J. NCI (1954); 14(6)1281–1433
  • Silerberg M. Osteoarthrosis and osteroporo-sis in senile mice. Gerontologia (1962); 6: 91–101
  • Solleveld H. A., Haseman J. K., McConnell E. E. Natural history of body weight gain, survival, and neoplasia in the Fischer 344 Rat. 1984
  • Noell W. K., Walker V. S., Kang B. S., Berman S. Retinal damage by light in rats. Invest. Ophthalmol. (1966); 5: 450–472
  • Miller R. R., Ayres J. A., Rampy L. W., Smith J. M., Weil C. S., Clary J. J., Jersey G. C. Ethyl acrylate vapor inhalation study. Three-month interim sacrifice of rats and 6-month interim sacrifice of rats and mice. Abstracts of Papers. 19th Annual Meeting of the Society of Toxicology A53. 1980
  • Miller R. R, Ayres J. A., Young J. T., Park C. N., Jersey G. C. Ethyl acrylate: 18-month vapor inhalation study in mice. Dow Chemical U.S.A. Report. 1982
  • Gushow T. S., Bell T. J., Burek J. D., Potts W. J., McKenna M. J. Nitroethane: A 13-week inhalation toxicity study in rats and mice. The Toxicologist. (1982); 2(1)160
  • Klimisch H. J. Carcinogenicity of acrylates: Long-term inhalation studies on methyl acrylate (MA) and n-butyl acrylate (BA) in rats. Toxicologist (1984); 4(1)53
  • Stott W. T., McKenna M. J. The comparative absorption and excretion of chemical vapors by the upper, lower, and intact respiratory tract of rats. Fundam. Appl. Toxicol. (1984); 4: 594–602
  • Swenberg J. A., Kerns W. D., Mitchell R. I., Gralla E. J., Pavkov K. L. Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor. Cancer Res. (1980); 40: 3398–3402
  • Kruysse A., Feron V. J., Til H. P. Repeated exposure to acetaldehyde vapor. Arch. Environ. Healt. (1975); 30: 449–452
  • Woutersen R. A., Appelman L. M., Feron V. J., Van Der Heijden C. A. Inhalation toxicity of acetaldehyde in rats. II. Carcinogenicity study: Interim results after 15 months. Toxicology (1984); 31: 123–133
  • Marenpot R. R. NTP Technical Report on the Carcinogenesis Bioassay of Ethyl Acrylate in Rats and Mice. (DRAFT). National Toxicology Program. (1983), NTP TR No. 259

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.