Protective role of peroxisome proliferator-activated receptor-β/δ against pulmonary oxygen toxicity mediated through changes in NOS expression levels

REFERENCES

• Balentine JD: Pathology of oxygen toxicity. New York: Academic Press; 1982.
   Google Scholar
• Wispe JR, Roberts RJ: Molecular basis of pulmonary oxygen toxicity. Clin Perinatol. 1987;14(3):651–666.
   PubMed Web of Science ®Google Scholar
• Jamieson D, Chance B, Cadenas E, Boveris A: The relation of free radical production to hyperoxia. Annu Rev Physiol. 1986;48:703–719.
   PubMed Web of Science ®Google Scholar
• Fisher AB, Forman HJ, Glass M: Mechanisms of pulmonary oxygen toxicity. Lung. 1984;162(5):255–259.
   PubMed Web of Science ®Google Scholar
• Enkhbaatar P, Lange M, Nakano Y, Hamahata A, Jonkam C, Wang J, Jaroch S, Traber L, Herndon D, Traber D: Role of neuronal nitric oxide synthase in ovine sepsis model. Shock. 2009;32(3):253–257.
   PubMed Web of Science ®Google Scholar
• Wang F, Li C, Liu W, Jin Y: Effect of exposure to volatile organic compounds (VOCs) on airway inflammatory response in mice. J Toxicol Sci. 2012;37(4):739–748.
   PubMed Web of Science ®Google Scholar
• Braman RS, Hendrix SA: Nanogram nitrite and nitrate determination in environmental and biological materials by vanadium (III) reduction with chemiluminescence detection. Anal Chem. 1989;61(24):2715–2718.
   PubMed Web of Science ®Google Scholar
• Kelm M, Dahmann R, Wink D, Feelisch M: The nitric oxide/superoxide assay. Insights into the biological chemistry of the NO/O-2. interaction. J Biol Chem. 1997;272(15): 9922–9932.
   PubMed Web of Science ®Google Scholar
• Pepperl S, Dorger M, Ringel F, Kupatt C, Krombach F: Hyperoxia upregulates the NO pathway in alveolar macrophages in vitro: role of AP-1 and NF-kappaB. Am J Physiol Lung Cell Mol Physiol. 2001;280(5):L905–L913.
   PubMed Web of Science ®Google Scholar
• Turanlahti M, Pesonen E, Lassus P, Andersson S: Nitric oxide and hyperoxia in oxidative lung injury. Acta Paediatr. 2000;89(8):966–970.
   PubMed Web of Science ®Google Scholar
• Arkovitz MS, Szabó C, Garcia VF, Wong HR, Wispé JR: Differential effects of hyperoxia on the inducible and constitutive isoforms of nitric oxide synthase in the lung. Shock. 1997;7(5):345–350.
   PubMed Web of Science ®Google Scholar
• Capellier G, Maupoil V, Boillot A, Kantelip JP, Rochette L, Regnard J, Barale F: L-NAME aggravates pulmonary oxygen toxicity in rats. Eur Respir J. 1996;9(12):2531–2536.
   PubMed Web of Science ®Google Scholar
• Beckman JS: The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J Dev Physiol. 1991;15(1):53–59.
   PubMedGoogle Scholar
• Beckman JS, Koppenol WH: Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol. 1996;271(5 Pt 1):C1424–C1437.
   PubMed Web of Science ®Google Scholar
• Cucchiaro G, Tatum AH, Brown MC, Camporesi EM, Daucher JW, Hakim TS: Inducible nitric oxide synthase in the lung and exhaled nitric oxide after hyperoxia. Am J Physiol. 1999;277(3 Pt 1):L636–L644.
   PubMed Web of Science ®Google Scholar
• Kondrikov D, Elms S, Fulton D, Su Y: eNOS-beta-actin interaction contributes to increased peroxynitrite formation during hyperoxia in pulmonary artery endothelial cells and mouse lungs. J Biol Chem. 2010;285(46):35479–35487.
   PubMed Web of Science ®Google Scholar
• Suborov EV, Smetkin AA, Kondratiev TV, Valkov AY, Kuzkov VV, Kirov MY, Bjertnaes LJ: Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy. BMC Anesthesiol. 2012;12:10.
   PubMedGoogle Scholar
• Lange M, Hamahata A, Traber DL, Nakano Y, Traber LD, Enkhbaatar P: Specific inhibition of nitric oxide synthases at different time points in a murine model of pulmonary sepsis. Biochem Biophys Res Commun. 2011;404(3):877–881.
   PubMed Web of Science ®Google Scholar
• You P, Yao J, Bao XC, Ma J, Zhang S, Fang YQ: The variation of PPAR pathway molecules in the lung tissue of rats under hyperbaric oxygen exposure. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2012;28(4):298–300.
   PubMedGoogle Scholar
• Kersten S, Desvergne B, Wahli W: Roles of PPARs in health and disease. Nature. 2000;405(6785):421–424.
   PubMed Web of Science ®Google Scholar
• Rosenson RS, Wright RS, Farkouh M, Plutzky J: Modulating peroxisome proliferator-activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects. Am Heart J. 2012;164(5):672–680.
   PubMed Web of Science ®Google Scholar
• Piqueras L, Reynolds AR, Hodivala-Dilke KM, Alfranca A, Redondo JM, Hatae T, Tanabe T, Warner TD, Bishop-Bailey D: Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis. Arterioscler Thromb Vasc Biol. 2007;27(1):63–69.
   PubMed Web of Science ®Google Scholar
• Wang D, Ning W, Xie D, Guo L, DuBois RN: Peroxisome proliferator-activated receptor delta confers resistance to peroxisome proliferator-activated receptor gamma-induced apoptosis in colorectal cancer cells. Oncogene. 2012;31(8):1013–1023.
   PubMed Web of Science ®Google Scholar
• Barroso E, Eyre E, Palomer X, Vázquez-Carrera M: The peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) agonist GW501516 prevents TNF-alpha-induced NF-kappaB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1. Biochem Pharmacol. 2011;81(4):534–543.
   PubMed Web of Science ®Google Scholar
• Di Paola R, Briguglio F, Paterniti I, Mazzon E, Oteri G, Militi D, Cordasco G, Cuzzocrea S: Emerging role of PPAR-beta/delta in inflammatory process associated to experimental periodontitis. Mediators Inflamm. 2011;2011:787159.
   PubMed Web of Science ®Google Scholar
• Kapoor A, Shintani Y, Collino M, Osuchowski MF, Busch D, Patel NS, Sepodes B, Castiglia S, Fantozzi R, Bishop-Bailey D, Mota-Filipe H, Yaqoob MM, Suzuki K, Bahrami S, Desvergne B, Mitchell JA, Thiemermann C: Protective role of peroxisome proliferator-activated receptor-beta/delta in septic shock. Am J Respir Crit Care Med. 2010;182(12):1506–1515.
   PubMed Web of Science ®Google Scholar
• Jimenez R, Sanchez M, Zarzuelo MJ, Romero M, Quintela AM, López-Sepúlveda R, Galindo P, Gómez-Guzmán M, Haro JM, Zarzuelo A, Pérez-Vizcaíno F, Duarte J: Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway. J Pharmacol Exp Ther. 2010;332(2): 554–561.
   PubMed Web of Science ®Google Scholar
• Zingarelli B, Piraino G, Hake PW, O'Connor M, Denenberg A, Fan H, Cook JA: Peroxisome proliferator-activated receptor {delta}1 regulates inflammation via NF-{kappa}B signaling in polymicrobial sepsis. Am J Pathol. 2010;177(4):1834–1847.
   PubMed Web of Science ®Google Scholar
• Galuppo M, Di Paola R, Mazzon E, Genovese T, Crisafulli C, Paterniti I, Cuzzocrea E, Bramanti P, Kapoor A, Thiemermann C, Cuzzocrea S: Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study. J Inflamm (Lond). 2010;7:12.
   PubMedGoogle Scholar
• Chen HI, Yeh DY, Liou HL, Kao SJ: Insulin attenuates endotoxin-induced acute lung injury in conscious rats. Crit Care Med. 2006;34(3):758–764.
   PubMed Web of Science ®Google Scholar
• De Sanctis GT, MacLean JA, Hamada K, Mehta S, Scott JA, Jiao A, Yandava CN, Kobzik L, Wolyniec WW, Fabian AJ, Venugopal CS, Grasemann H, Huang PL, Drazen JM: Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. J Exp Med. 1999;189(10):1621–1630.
   PubMed Web of Science ®Google Scholar
• Kavdia M, Popel AS: Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure. J Appl Physiol. 2004;97(1):293–301.
   PubMed Web of Science ®Google Scholar
• Gu X, El-Remessy AB, Brooks SE, Al-Shabrawey M, Tsai NT, Caldwell RB: Hyperoxia induces retinal vascular endothelial cell apoptosis through formation of peroxynitrite. Am J Physiol Cell Physiol. 2003;285(3):C546–C554.
   PubMed Web of Science ®Google Scholar
• Li LF, Liao SK, Lee CH, Huang CC, Quinn DA: Involvement of Akt and endothelial nitric oxide synthase in ventilation-induced neutrophil infiltration: a prospective, controlled animal experiment. Crit Care. 2007;11(4):R89.
   PubMed Web of Science ®Google Scholar
• Jung F, Palmer LA, Zhou N, Johns RA: Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes. Circ Res. 2000;86(3):319–325.
   PubMed Web of Science ®Google Scholar
• Ricciardolo FL, Sterk PJ, Gaston B, Folkerts G: Nitric oxide in health and disease of the respiratory system. Physiol Rev. 2004;84(3):731–765.
   PubMed Web of Science ®Google Scholar
• Singh K, Balligand JL, Fischer TA, Smith TW, Kelly RA: Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells. Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and STAT1 alpha. J Biol Chem. 1996;271(2):1111–1117.
   PubMed Web of Science ®Google Scholar
• Galuppo M, Di Paola R, Mazzon E, Esposito E, Paterniti I, Kapoor A, Thiemermann C, Cuzzocrea S: GW0742, a high affinity PPAR-beta/delta agonist reduces lung inflammation induced by bleomycin instillation in mice. Int J Immunopathol Pharmacol. 2010;23(4):1033–1046.
   PubMed Web of Science ®Google Scholar