Enkephalinase Inhibitors Potentiate Substance P-Induced Secretion of ³⁵SO₄-Macromolecules from Ferret Trachea

References

• Nadel J A, Widdicombe J H, Peatfield A C. Regulation of airway secretions, ion transport and water movement. Handbook of Physiology, A P Fishman, A B Fisher. The American Physiological Society, Bethesda, MD, 419–445
   Google Scholar
• Borson D B, Charlin M, Gold B D, Nadel J A. Neural regulation of 35SO4-macromolecule secretion from tracheal glands of ferrets. J Appl Physiol 1984; 57: 457–466
   PubMed Web of Science ®Google Scholar
• Peatfield A C, Richardson P S. Evidence for non-cholinergic non-adrenergic nervous control of mucous secretion into the cat trachea. J Physiol (London) 1983; 342: 335–345
   Google Scholar
• Lundberg J M, Saria A, Brodin E, Rosell S, Folkers K. A substance P antagonist inhibits vagally induced increase in vascular permeability and bronchial smooth muscle contraction in the guinea pig. Proc Natl Acad Sci USA 1983; 80: 1120–1124
   PubMed Web of Science ®Google Scholar
• Lundberg J M, Martling C R, Saria A. Substance P and capsaicin-induced contraction of human bronchi. Acta Physiol Scand 1983; 119: 49–53
   PubMedGoogle Scholar
• Ghatei M A, Sheppard M N, O'Shaughnessy D J, Adrian T E, Mc Gregor G P, Polak J M, Bloom S R. Regulatory peptides in the mammalian respiratory tract. Endocrinology 1982; 111: 1248–1254
   PubMed Web of Science ®Google Scholar
• Lundberg J M, Hokfelt T, Martling C-R, Saria A, Cuello S. Substance P-immunoreactive sensory nerves in the lower respiratory tract of various animals including man. Cell Tissue Research 1984; 235: 251–261
   PubMed Web of Science ®Google Scholar
• Gashi A A, Borson D B, Basbaum C B, Nadel J A. Neuropeptides degranulate serous cells of ferret tracheal glands. Am J Physiol 1986; 251: C223–C229, (Cell Physiol 20)
   PubMed Web of Science ®Google Scholar
• Baker A P, Hillegass L M, Holden D A, Smith W J. Effect of kallidin, substance P and other basic polypeptides on the production of respiratory macromolecules. Am Rev Respir Dis 1977; 115: 811–817
   PubMed Web of Science ®Google Scholar
• Coles S J, Bhaskar K R, O'Sullivan D D, Neill K H, Reid L M. Airway mucus: Composition and regulation of its secretion by neuropeptides in vitro. Mucus and Mucosa, J Nugent, M O'Connor. Pitman Publishing Co., London 1984; 40–60, CIBA Foundation Symposium 109
   Google Scholar
• Coles S J, Neill K H, Reid L M. Potent stimulation of glycoprotein secretion in canine trachea by substance P. J Appl Physiol.: Respirat Environ Exercise Physiol 1984; 57: 1323–1327
   PubMed Web of Science ®Google Scholar
• Growcott J W, Tarpey A V. Effects of substance P-(1–9) nonapeptide amide on inactivation of substance P in vitro. Eur J Pharm 1982; 84: 107–109
   PubMed Web of Science ®Google Scholar
• Cascieri M A, Bull H G, Mumford R A, Patchett A A, Thornberry N A, Liang T. Carboxy-terminal tripeptidyl hydrolysis of substance P by purified rabbit lung angiotensin-converting enzyme and the potentiation of substance P activity in vivo by captopril and MK-422. Mol Pharmacol 1984; 25: 287–293
   PubMed Web of Science ®Google Scholar
• Hanson G R, Lovenberg W. Elevation of substance P-like immunoreactivity in rat central nervous system by protease inhibitors. J Neurochem 1980; 35: 1370–1374
   PubMed Web of Science ®Google Scholar
• Chubb I W, Hodgson A J, White G H. Acetylcholinesterase hydrolyzes substance P. Neuroscience 1980; 5: 2065–2072
   PubMed Web of Science ®Google Scholar
• Skidgel R A, Engelbrecht A, Johnson A R, Erdos E G. Hydrolysis of substance P and neurotensin by converting enzyme and neutral endoproteinase. Peptides 1984; 5: 769–776
   PubMed Web of Science ®Google Scholar
• Llorens C, Schwartz J-C. Enkephalinase activity in rat peripheral organs. Eur J Pharmacol 1981; 69: 113–116
   PubMed Web of Science ®Google Scholar
• Johnson A R, Ashton J, Schulz W W, Erdos E G. Neutral metalloendopeptidase in human lung tissue and cultured cells. Am Rev Respirat Dis 1985; 132: 564–568
   PubMed Web of Science ®Google Scholar
• Bolton A E, Hunter W M. The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acetylating agent. Application to radioimmunoassay. Biochem J 1973; 133: 529–539
   PubMed Web of Science ®Google Scholar
• Mc Conahey P, Dixon F. Chapter 11. Radioiodination of proteins by the use of the choramine-T method. Methods in Enzymology 1980; vol. 70: 219–213
   Google Scholar
• Roques B P, Fournie-Zaluski C M, Soroca E, Lecomte J M, Malfroy B, Llorens C, Schwartz J-C. The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice. Nature 1980; 288: 286–288
   PubMed Web of Science ®Google Scholar
• Chaillet P, Marcais-Collado H, Costentin J, Yi C-C, De La Baume S, Schwartz J C. Inhibition of enkephalin metabolism by, and antinociceptive activity of, bestatin, an aminopeptidase inhibitor. Eur J Pharmacol 1983; 86: 329–336
   PubMed Web of Science ®Google Scholar
• Corrales R J, Nadel J A, Widdicombe J H. Source of the fluid component of secretions from tracheal submucosal glands in cats. J Appl Physiol.: Respirat Environ Exercise Physiol 1985; 56: 1076–1082
   Web of Science ®Google Scholar
• Zar J H. Multiple comparisons. Biostatistical Analysis. Prentice Hall, Inc., Englewood Cliffs, NJ 1974; 151–155
   Google Scholar
• Malfroy B, Schwartz J-C. Comparison of dipeptidyl carboxypeptidase and endopeptidase activities in the three enkephalin-hydrolysing metallopeptidases: “Angiotensin-converting enzyme,” thermolysin and “enkephalinase.”. Biochem Biophys Res Commun 1985; 130: 372–378
   PubMed Web of Science ®Google Scholar
• Huidobro-Toro J P, Chelala C A, Bahouth S, Nodar R, Musacchio J M. Fading and tachyphylaxis to the contractile effects of substance P in the guinea-pig ileum. Eur J Pharmacol 1982; 81: 21–34
   PubMed Web of Science ®Google Scholar
• Peatfield A C, Barnes P J, Bratcher C, Nadel J A, Davis B. Vasoactive intestinal peptide stimulates tracheal submucosal gland secretion in ferret. Am Rev Respir Dis 1983; 128: 89–93
   PubMed Web of Science ®Google Scholar
• Lee C M, Sandberg B EB, Henley M R, Iversen L L. Purification and characterization of a membrane-bound substance P degrading enzyme from human brain. Eur J Biochem 1981; 114: 315–327
   PubMedGoogle Scholar
• Matsas R, Kenny A J, Turner A J. The metabolism of neuropeptides; the hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11. Biochem J 1984; 223: 433–440
   PubMed Web of Science ®Google Scholar
• Cutz E, Chan W, Track N S. Bombesin, calcitonin and leu-enkephalin immunoreactivity in endocrine cells of human lung. Experentia 1981; 37: 765–767
   PubMedGoogle Scholar
• Conlon J M, Sheehan L. Conversion of substance P to C-terminal fragments in human plasma. Regulatory Peptides 1983; 7: 335–345
   PubMed Web of Science ®Google Scholar